在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

L2HGDH Antibody

  • 中文名稱:
    L2HGDH兔多克隆抗體
  • 貨號:
    CSB-PA864008ESR1HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA864008ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) L2HGDH Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    L2HGDH
  • 別名:
    2 hydroxyglutarate dehydrogenase antibody; Alpha hydroxyglutarate oxidoreductase antibody; Alpha ketoglutarate reductase antibody; C14orf160 antibody; Duranin antibody; FLJ12618 antibody; L alpha hydroxyglutarate dehydrogenase antibody; L-2-hydroxyglutarate dehydrogenase antibody; L-2-hydroxyglutarate dehydrogenase, mitochondrial antibody; L2HDH_HUMAN antibody; l2hgdh antibody; mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human L-2-hydroxyglutarate dehydrogenase, mitochondrial protein (1-220AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. In this study, we describe a large pedigree from Pakistan showing multiple neurological symptoms. Homozygosity mapping and Sanger sequencing revealed a novel missense mutation in L2HGDH gene. PMID: 29458334
    2. The mutations of the L2HGDH gene as the causes of L-2-hydroxyglutaric aciduria. PMID: 29980873
    3. c.845G>A (p.R282Q) in the exon 7 of the L2HGDH gene is associated with 2-hydroxyglutaric aciduria in Chinese family. PMID: 26829733
    4. Intragenic single nucleotide length polymorphisms and two extragenic microsatellites flanking the L2HGDH gene confirm the founder effect of c.241A>G mutation in the 14 studied cases. PMID: 24573090
    5. modest increases in intracellular 2-HG in acute myeloid leukaemia cells, as seen with the rs11554137 SNP, might enhance chemoresistance, or promote acquisition of leukaemia-iniating mutations PMID: 24606602
    6. Report ten novel mutations in the L2HGDH gene in patients with L-2-hydroxyglutaric aciduria from different ethnic backgrounds. PMID: 18415700
    7. Report three unrelated Tunisian families containing seven patients with L2HGA mutations and inter-familial phenotype variability. PMID: 18780161
    8. L2HGDH mutation is not associated with glioblastoma. PMID: 21625441
    9. We did not find evidence for mutations in the genes D2HGDH and L2HGDH as an alternative mechanism for raised 2-hydroxyglutarate levels in brain tumours PMID: 20727073
    10. Exonic mutations in the L2HGDH gene in Staffordshire bull terriers have been identified and associated with epilepsy. PMID: 20852250
    11. analysis of genetic heterogeneity in D-2-hydroxyglutaric aciduria PMID: 20020533
    12. The phenotype, including neurological manifestations and urinary levels of alpha-hydroxyglutarate, is reported and the phenotype-genotype relationship, is evaluated. PMID: 20052767
    13. we present three novel mutations (Gln197X, Gly211Val and c.540+1 G>A), which increase the present deleterious collection of L2HGDH gene up to 35 mutationsthat we have compiled in this study. PMID: 19911013
    14. encodes a putative mitochondrial protein with homology to FAD-dependent oxidoreductases; a mutant gene is accociated with L-2-hydroxyglutaric aciduria.propose to name the gene duranin PMID: 15385440
    15. data indicate that l-2-hydroxyglutaric aciduria is due to a deficiency in l-2-hydroxyglutarate dehydrogenase PMID: 16005139
    16. Indicate that 2-ketoglutaric acid is the metabolic precursor of L-2-hydrosyglutaric acid in L-2-hydroxyglutaric acid aciduria. PMID: 17876720
    17. We successfully treated an adult patient with L-2-hydroxyglutaric aciduria using FAD and levocarnitine. PMID: 18362286
    18. Data show that L-2-hydroxyglutaric aciduria and brain tumors in children with mutations in the L2HGDH gene in exon 3 (c.292C-->T) and in exon 7 (c.887T-->A). PMID: 18671189

    顯示更多

    收起更多

  • 相關疾病:
    L-2-hydroxyglutaric aciduria (L2HGA)
  • 亞細胞定位:
    Mitochondrion.
  • 蛋白家族:
    L2HGDH family
  • 組織特異性:
    Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow.
  • 數據庫鏈接:

    HGNC: 20499

    OMIM: 236792

    KEGG: hsa:79944

    STRING: 9606.ENSP00000267436

    UniGene: Hs.256034



主站蜘蛛池模板: 人妻无码视频一区二区三区| 无码日韩精品一区二区三区免费| 久久久久久久久久久久久9999| 无码国产精品一区二区免费式芒果| 日日碰狠狠躁久久躁2023| 日本丰满岳乱妇在线观看| 国产偷国产偷亚州清高app| 新国产三级视频在线播放| 麻花传媒mv在线观看| 宅男午夜成年影视在线观看| 成人无码亚洲精品无码| 日产精品一区二区| 国产午夜鲁丝无码拍拍| 熟女chachacha性少妇| 毛片无码免费无码播放| 青青青伊人色综合久久| 尤物av无码国产在线看| 久久被窝亚洲精品爽爽爽| 久久久久久a亚洲欧洲av冫| 人妻另类 专区 欧美 制服| 天天综合色天天综合色h| 久久99精品国产99久久6男男| 肥老熟妇伦子伦456视频| 国产午夜亚洲精品不卡| 中文字幕精品久久久久人妻红杏| 伊人久久大香线蕉亚洲五月天| 久久久久国产综合av天堂| 国产97人人超碰caoprom| 久久精品日韩av无码| 蜜臀av在线播放| 蜜桃av无码免费看永久| 51福利国产在线观看午夜天堂| 欧美与黑人午夜性猛交久久久 | 国产99久久久国产无需播放器 | 国产高清在线a视频大全| 国产亚洲精品欧洲在线视频| 免费人成在线观看网站品爱网| 99久热re在线精品99re8热视频| 久久9精品区-无套内射无码| 亚洲免费福利在线视频| 台湾无码一区二区|