在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. GABRE Antibody

GABRE Antibody

  • 中文名稱：
    GABRE兔多克隆抗體
  • 貨號(hào)：
    CSB-PA004692
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of Jurkat cells using GABAA Rε Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    GABRE
  • 別名：
    GABA(A) receptor epsilon antibody; GABA(A) receptor subunit epsilon antibody; Gabre antibody; Gamma aminobutyric acid (GABA) A receptor epsilon antibody; Gamma aminobutyric acid receptor subunit epsilon antibody; Gamma-aminobutyric acid receptor subunit epsilon antibody; GBRE_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human GABAA Rε.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
  • 基因功能參考文獻(xiàn)：
    1. This study showed that in male groups, the expression of GABRE was generally lower in schizophrenia cases compared to the control. PMID: 25660468
    2. Data indicate that GABA(A) receptor subunit epsilon (GABRE) approximately miR-452 approximately miR-224 locus is downregulated and hypermethylated in prostate cancer and is a promising epigenetic candidate biomarker for prostate cancer diagnosis and prognosis. PMID: 24737792
    3. GABRE protein levels were significantly increased in schizophrenia, major depressive disorder, and bipolar disorder patients' lateral cerebellum compared to controls. PMID: 24022508
    4. Using published alpha subunit data we identified two principal components labeled 'Decreasing' (alpha2, alpha5, beta1, gamma1 and gamma3) and 'Dynamic' (alpha1, alpha4, beta2 and gamma2) responsible for 84% of variation in GABA(A)R subunit development. PMID: 20609421
    5. Analysis of epilepsy inter-patient variability of eleven highly expressed GABAAR subunit mRNAs found seven of the subunits varied between patients, as did whole cell GABAAR currents. PMID: 15755675
    6. We report here that the GABA-activated current can be potentiated at pH 8.4 for both alphabeta and alphabeta gamma subunit-containing receptors, but only at GABA concentrations below the EC40. PMID: 15946973
    7. We infer that activation by anesthetics and GABA induces a similar conformational change at the M2 segment 6' position that is related to channel opening. PMID: 17293408
    8. Increased intracortical excitability is noted in subjects affected by the GABA A receptor gamma 2 subunit (GABRG2 Arg43Glu) mutation; findings are likely to represent an important clue to mechanisms linking this gene defect and the epilepsy phenotype. PMID: 17615250
    9. Increased expression of epsilon, in conjunction with alpha2 and beta3 subunits, results in expression of GABAA receptors with correspondingly altered rectification, deactivation and levels of spontaneous openings, but not increased total current density. PMID: 17714454
    10. Although GABRE genes did not show positive association, further studies are necessary to consider the role of other GABA receptor genes in migraine susceptibility PMID: 19087248

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ligand-gated ion channel (TC 1.A.9) family, Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily, GABRE sub-subfamily
  • 組織特異性：
    Expressed in many tissues. Highest levels of expression in adult heart and placenta.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4085

    OMIM: 300093

    KEGG: hsa:2564

    STRING: 9606.ENSP00000359353

    UniGene: Hs.22785



主站蜘蛛池模板： 成人18禁深夜福利网站app免费| 国产妇女馒头高清泬20p多| 少妇av射精精品蜜桃专区| 成人性生交大片免费看r链接| 久久综合久久鬼色| 中文字幕av伊人av无码av| 国产农村妇女aaaaa视频| 国产亚洲精品久久久性色情软件| 热99re久久精品国产首页免费| 国产精品女主播在线视频| 亚洲欧美另类精品二区| 一本色综合亚洲精品蜜桃冫| 精品国产精品国产偷麻豆 | 青草青草久热国产精品| 怀孕挺大肚子疯狂高潮av毛片| 午夜性爽视频男人的天堂| 国产精品久久久久久久久鸭| 性史性农村dvd毛片| 国产女人的高潮国语对白| 女人被黑人躁得好爽视频| 99久热re在线精品视频| 免费无码黄十八禁网站在线观看| 国产亚洲精品久久yy50| 亚洲精品乱码久久久久久久久久久久| av午夜久久蜜桃传媒软件| 无码国产偷倩在线播放| 国产精品久久久久久日本| 亚洲精品久久久av无码专区| 亚洲va中文字幕无码毛片| 久久天天躁狠狠躁夜夜av| 国产α片免费观看在线人| 欧美成人精品三级网站视频| 国产精品一区二区高清在线| 亚洲熟女乱综合一区二区| 国产成人久久a免费观看| 99热精品国自产拍天天拍| 国产综合一区二区三区黄页秋霞 | 中文字幕精品久久久久人妻红杏ⅰ | 精品久久久久久久国产潘金莲 | 久久精品女同亚洲女同| 日本护士毛茸茸|