Recombinant Fundulus heteroclitus Type II iodothyronine deiodinase (dio2)

in vitro E.coli expression system

中文名稱：

Recombinant Fundulus heteroclitus Type II iodothyronine deiodinase(dio2)
貨號：

CSB-CF301283FDK
說明書：

MSDS Datasheet
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

dio2
Uniprot No.：

P79747
別名：

dio2; Type II iodothyronine deiodinase; 5DII; DIOII; Type 2 DI; Type-II 5'-deiodinase
種屬：

Fundulus heteroclitus (Killifish) (Mummichog)
蛋白長度：

full length protein
表達區域：

1-266
氨基酸序列

MGSASEDLLVTLQILPGFFSNCLFLALYDSVVLVKRVVALLSRSRSAGCGEWRRMLTSEG LRSIWNSFLLDAHKQVKLGCEAPNSKVVKVPDGPRWSSTVVPCGSRIQTGGECRLLDFES SDRPLVVNFGSATUPPFISHLPAFRQLVEDFSDVADFLLVYIDEAHPSDGWVAPQMGACS FSFRKHQNLEERIGAARKLIEHFSLPPQCQLVADCMDNNANVAYGVANERVCIVHQRKIA YLGGKGPFFYSLKDVRQWLELSYGRR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
基因功能參考文獻：
1. Divergent evolution of dio2 paralogs supports organ-specific timing of the TH-dependent events governing the phenotypic plasticity required for migration to sea. PMID: 25802152
亞細胞定位：

Membrane; Single-pass membrane protein.
蛋白家族：

Iodothyronine deiodinase family
數據庫鏈接：

UniGene: Fhe.427