在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Thyrotropin receptor (Tshr)-VLPs

  • 中文名稱:
    Recombinant Rat Thyrotropin receptor (Tshr)-VLPs
  • 貨號:
    CSB-MP025131RA
  • 規格:
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Thyroid-stimulating hormone receptor;TSH-R
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Mammalian cell
  • 表達區域:
    22-764aa
  • 氨基酸序列
    RGCTSPPCECHQEDDFRVTCKELHQIPSLPPSTQTLKLIETHLKTIPSLAFSSLPNISRIYLSIDATLQRLEPHSFYNLSKMTHIEIRNTRSLTYIDPDALTELPLLKFLGIFNTGLRIFPDLTKIYSTDVFFILEITDNPYMTSVPENAFQGLCNETLTLKLYNNGFTSIQGHAFNGTKLDAVYLNKNKYLTAIDKDAFGGVYSGPTLLDVSSTSVTALPSKGLEHLKELIAKNTWTLKKLPLSLSFLHLTRADLSYPSHCCAFKNQKKIRGILESLMCNESSIRNLRQRKSVNVMRGPVYQEYEEGLGDNHVGYKQNSKFQEGPSNSHYYVFFEEQEDEIIGFGQELKNPQEETLQAFDSHYDYTVCGDNEDMVCTPKSDEFNPCEDIMGYKFLRIVVWFVSPMALLGNVFVLFVLLTSHYKLTVPRFLMCNLAFADFCMGVYLLLIASVDLYTHTEYYNHAIDWQTGPGCNTAGFFTVFASELSVYTLTVITLERWYAITFAMRLDRKIRLRHAYTIMAGGWVSCFLLALLPMVGISSYAKVSICLPMDTDTPLALAYIALVLLLNVVAFVIVCSCYVKIYITVRNPQYNPRDKDTKIAKRMAVLIFTDFMCMAPISFYALSALMNKPLITVTNSGVLLVLFYPLNSCANPFLYAIFTKAFQRDVFILLSKFGLCKHQAQAYQAQRVCPNNNTGIQIQKIPQDTRQSLPNVQDTYEPLGSSHLTPKLQGRISEEYTQTAL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    C-terminal 10xHis-tagged
    If you have specified tag type, please tell us and we will check if it's possible to develop.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from PBS, 6% Trehalose, pH 7.4.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項:
    The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex. Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
  • 基因功能參考文獻:
    1. Data suggest that functional thyroid-stimulating hormone receptor is present in the caudal brainstem and hypothalamic nuclei of relevance for feeding control as a possibly uncleaved holoreceptor, and highlights a hindbrain component to central thyroid-stimulating hormone inhibition of food intake. PMID: 27059392
    2. TSH signal transduction in cultured tanycytes signals via G alphas to increase cAMP via an alternative G protein to increase phosphorylation of ERK1/2. PMID: 25878058
    3. Results show that Tshr mRNA levels were up-regulated during differentiation of brown adipocytes. During the differentiation of brown adipocytes PMID: 25662278
    4. Higher TSH level in the BN strain appears to reflect an adjustment of the feedback loop to reduced thyrocyte sensitivity to TSH secondary to reduced TSHR expression. PMID: 17640981
    5. TSHR is present and functional in hepatocytes. PMID: 19187127
    6. Data indicate that the presence of thyrostimulin in the ovary suggests that it may have a primitive function in reproduction when it activates ovarian TSHR. PMID: 19955180
    7. Developmental profiles of TSH, sex steroids, and their receptors in the thyroid and their relevance to thyroid growth in immature rats PMID: 11755178
    8. Identical amino acid residues in homologous receptors can exhibit distinct functions. Role of ionic strength (Na+) on signaling differs in the three receptors. PMID: 12588044
    9. mutation effects vary with the ambient iodide supply and could be masked in regions of high iodine intake PMID: 15691889

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family, FSH/LSH/TSH subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 久久国产亚洲精品无码| 亚洲精品一区二区久久| 日韩精品人妻中文字幕有码| 亚洲欧美日韩在线码| 先锋影音av资源站av| 国产亚洲欧美日韩俺去了| 无码粉嫩虎白一线天在线观看| 少妇愉情理伦片丰满丰满午夜| 97人妻无码专区| 伊人久久大香线蕉成人| 乱人伦人妻精品一区二区| 人人爽人人澡人人高潮| 国产开嫩苞实拍在线播放视频| 美国一区二区三区无码视频| 精品国产av一二三四区| 韩国精品一区二区三区四区| 精品国产一二三产品区别在哪| 久久精品娱乐亚洲领先| 国产一线二线三线女| 国产精品无码av天天爽| 国产成人美女视频网站| 久久久国产精品人人片| 999zyz玖玖资源站永久| 毛茸茸的中国女bbw| 久久精品国产一区二区免费| 无码潮喷a片无码高潮视频| 一本一道波多野结衣av一区| 中文字幕av中文字无码亚| 人成午夜大片免费视频| 亚洲色成人网站www永久| 成人免费直播| 九色精品国产成人综合网站| 精品久久久久久中文字幕202| 国产美女极度色诱视频www| 人妻换人妻仑乱| 强伦姧人妻免费无码电影| 亚洲成av人片天堂网| 欧美性生交大片18禁止| 看成年全黄大色黄大片| 成 人 网 站 免费 在线| 精品乱码一区内射人妻无码|