在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Somatostatin receptor type 1 (Sstr1)

  • 中文名稱:
    大鼠Sstr1重組蛋白
  • 貨號:
    CSB-CF022724RA
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Sstr1; Somatostatin receptor type 1; SS-1-R; SS1-R; SS1R; SRIF-2
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-391
  • 氨基酸序列
    MFPNGTAPSPTSSPSSSPGGCGEGVCSRGPGSGAADGMEEPGRNSSQNGTLSEGQGSAIL ISFIYSVVCLVGLCGNSMVIYVILRYAKMKTATNIYILNLAIADELLMLSVPFLVTSTLL RHWPFGALLCRLVLSVDAVNMFTSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG VWVLSLLVILPIVVFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAIC LCYVLIIAKMRMVALKAGWQQRKRSERKITLMVMMVVMVFVICWMPFYVVQLVNVFAEQD DATVSQLSVILGYANSCANPILYGFLSDNFKRSFQRILCLSWMDNAAEEPVDYYATALKS RAYSVEDFQPENLESGGVFRNGTCASRISTL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for somatostatin with higher affinity for somatostatin-14 than -28. This receptor is coupled to phosphotyrosine phosphatase and Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
  • 基因功能參考文獻:
    1. In the jejunums of Cryptosporidium-parvum-infected rats, daily octreotide therapy decreased mRNA levels of SSTR1 on day 14 post-infection, although it increased mRNA levels of SSTR1 on day 50 post-infection. Specific SSTRs may regulate the inflammatory pathway in the rat intestinal inflammation model. PMID: 29522573
    2. All SSTR1-5 proteins were observed at embryonal day 10 and increased with time in major structures, but the localization varied between the different subtypes. Only SSTR1 protein co-localized to a higher extent with the islet hormones studied. PMID: 25926390
    3. up-regulated SSTR1 contributed to neuronal apoptosis after intracerebral hemorrhage, which was accompanied with reduced expression of bcl-2. PMID: 25035058
    4. This study demonistrated that sstr1 and Melanin-concentrating hormone colization in neuron in the lateral hypothalamus (LH) and zona incerta (ZI), but MCHR1 mRNA is widely expressed throughout the brain. PMID: 24978951
    5. Most neuropeptide Y expressing receptors in the arcuate nucleus coexpress somatostatin receptor subtype 1. PMID: 15618885
    6. data suggest that higher expression of somatostatin receptor subtype 1 and 2 mRNA induced by the gsp oncogene may be a mechanism by which gsp-positive tumors show a greater response to somatostatin PMID: 16379030
    7. the sequential activation of JAK2, SHP-2, and Src conveys the molecular signaling from SSTR1 to the activation of this phosphatase that is responsible for the final biological effects of SST PMID: 17021051
    8. Sstr1 mediates a dynamic process of endocytosis, recycling, and re-endocytosis of its cognate ligand. PMID: 17170097
    9. All five SSTR are expressed in splanchnic blood vessels. Cirrhosis reduces expression of SSTR1 in portal vein. PMID: 17617126
    10. The combined activation of SSTR1 and -2 shows a partial synergism as far as antiproliferative activity. PMID: 18566118
    11. Postsynaptic localization of sst(1) receptors and synaptic connectivity in the ARC undergo pronounced remodeling in parallel with the GH rhythm. PMID: 19553459

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Brain, pituitary, islet, jejunum, stomach, heart, spleen.
  • 數據庫鏈接:


主站蜘蛛池模板: 无码精品久久久天天影视| 亚洲午夜福利av一区二区无码| 波多野42部无码喷潮| 亚洲色自偷自拍另类小说| 最新国产久免费视频在线观看| 亚洲高清乱码午夜电影网制服| 色欲久久久中文字幕综合网| 夫妇交换性三中文字幕| 久久国产成人精品国产成人亚洲| 欧美变态暴力牲交videos| 久久精品国产99久久无毒不卡| 2020精品国产a不卡片| 天天综合网天天综合色| 亚洲国产长腿丝袜av天堂| 成人免费视频在线观看| 变态另类牲交乱| 137肉体摄影日本裸交| 国产乱色国产精品播放视频 | 熟妇女人妻丰满少妇中文字幕 | 精品国产三级a∨在线| 欧美牲交a欧美在线| 中文无码伦av中文字幕在线| 久久人妻夜夜做天天爽| 男女啪啪永久免费观看网站| 少妇性俱乐部纵欲狂欢电影| 久久婷婷国产剧情内射白浆| 波多野结衣一区二区免费视频| 特黄aaaaaaa片免费视频| 福利一区二区三区视频在线观看| 男女性杂交内射妇女bbwxz| 久久精品免视看国产成人| 国产福利自产拍| 国产美女裸体无遮挡免费视频| 日韩欧美亚洲综合久久| 西西人体扒开下部试看120秒| 国产精品美女久久久浪潮av| 图片区小说区av区| 夜夜夜夜曰天天天天拍国产| 国产一区二区三区免费高清在线播放 | 在线精品自偷自拍无码| 亚洲一区二区三区国产精华液|