在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Gap junction alpha-4 protein (Gja4)

  • 中文名稱:
    大鼠Gja4重組蛋白
  • 貨號:
    CSB-CF009447RA
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Gja4
  • Uniprot No.:
  • 別名:
    Gja4; Cxn-37; Gap junction alpha-4 protein; Connexin-37; Cx37
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-333
  • 氨基酸序列
    GDWGFLEKLLDQVQEHSTVVGKIWLTVLFIFRILILGLAGESVWGDEQSDFECNTAQPGC TNVCYDQAFPISHIRYWVLQFLFVSTPTLIYLGHVIYLSRREERLRQKEGELRALPSKDP HVERALAAIEHQMAKISVAEDGRLRIRGALMGTYVISVLCKSVLEAGFLYGQWRLYGWTM EPVFVCQRAPCPHVVDCYVSRPTEKTIFIIFMLVVGVISLVLNLLELVHLLCRCVSREIK ARRDHDTRPAQGSASDPYPEQVFFYLPMGEGPSSPPCPTYNGLSSTEQNWANLTTEERLT STRPPPFVNAAPQGGQKSSSRPNSSASKKQYV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
  • 基因功能參考文獻:
    1. FFR levels increased along with decreased doses of siRNA CX37 lentivirus, indicating that siRNA CX37 lentivirus may reduce the risk of coronary atherosclerosis and provide a potential approach to treat coronary heart disease. PMID: 29049831
    2. Substituting alanine at serine residues 275, 302 and 328 eliminated Cx37-induced cell death, supported proliferation and reduced the GJCh closed state probability. PMID: 28818996
    3. Cx37-N55I and -Q58L mutations formed hemichannels with behavior and permeation properties similar to Cx37-WT (especially Q58L), but none of the mutants suppressed rat insulinoma cell proliferation. PMID: 25217644
    4. 7,12-Dimethylbenz[a]anthracene increases Cx37 and Cx43 expression prior to follicle loss and during follicle loss both Cx37 and Cx43 expressions are reduced in cultured rat ovaries. PMID: 24269759
    5. Differences in channel behavior of connexin 37 (Cx37) cytoplasmic loop mutants suggest that the Cx37-CT and pore-forming domains are both essential to growth suppression by Cx37. PMID: 24133065
    6. In the IVCs of IVC-banded ACF rats, which were exposed to a hemodynamic condition of high pressure and low flow velocity, the GJSNs and the TGJAs of Cx37 increased markedly. PMID: 20805582
    7. Renal epithelia express Cx37 in their basolateral membranes. PMID: 19828678
    8. Upregulation of connexin 37 mRNA after sciatic nerve injury causes thermal hyperalgesia; gap junctions thus may be responsible for this hyperexcitability. PMID: 11978404
    9. Demonstration of Cx37 as the dominant connexin expressed in the media of the caudal artery highlights the potential heterogeneity of Cx involvement in vascular smooth muscle. PMID: 12231561
    10. Renin-angiotensin system blockade corrects decreased expression of Cx37 and Cx40 in arterial endothelial cells of hypertensive rats, partly independently of blood pressure. PMID: 15016632
    11. Gap junctions, comprising connexins 37 and 40, transduce purinergic signals mediating renal autoregulation. PMID: 17928514
    12. Report regulation of connexin 37 gene expression during skeletal muscle regeneration in the adult rat. PMID: 19129462

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
  • 蛋白家族:
    Connexin family, Alpha-type (group II) subfamily
  • 組織特異性:
    Highly expressed in lung.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲国产精品无码中文字| 国语做受对白xxxxx在线| 国产免费午夜福利在线播放11| 99国产揄拍国产精品人妻| 免费人成激情视频在线观看冫| 国产精品无码无需播放器| 久久久久日韩精品免费观看| 国产精品久人妻精品老妇 | 曰批免费视频播放免费直播| 欧洲免费一区二区三区视频 | 亚洲高清专区日韩精品| 男女高潮喷水在线观看| 亚洲色大成网站www国产| 国产精品多人p群无码| 51被公侵犯玩弄漂亮人妻| 黑人巨大av无码专区| 大桥久未无码吹潮在线观看 | 蜜桃日本免费观看mv| 蜜臀av999无码精品国产专区| 乌克兰少妇videos高潮| 忘忧草www中文在线资源| 色情无码www视频无码区澳门| 波多野结衣办公室33分钟| 999国内精品永久免费视频| 无码吃奶揉捏奶头高潮视频| 青青草国产精品久久久久| 国产熟妇另类久久久久| 国产尤物av尤物在线看| 国产日韩亚洲大尺度高清| 国产九九九九九九九a片| 高清无码午夜福利视频| 欧美高潮喷水大叫| 永久不封国产av毛片| 毛片无码一区二区三区a片视频 | 日本免费视频| 久久/这里只精品99re66 | 成年黄页网站大全免费无码| 香蕉久久国产av一区二区| 午夜理论片yy8860y影院| 精品国产免费观看久久久| 国产精品毛片一区二区三区|