在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Frizzled-5 (Fzd5)

  • 中文名稱:
    大鼠Fzd5重組蛋白
  • 貨號:
    CSB-CF807066RA
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Fzd5; Frizzled-5; Fz-5
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    27-585
  • 氨基酸序列
    ASKAPVCQEITVPMCRGIGYNLTHMPNQFNHDTQDEAGLEVHQFWPLVEIHCSPDLRFFL CSMYTPICLPDYHKPLPPCRSVCERAKAGCSPLMRQYGFAWPERMSCDRLPVLGGDAEVL CMDYNRSEATTASPKSFPAKPTLPGPPGAPSSGGECPSGGPSVCTCREPFVPILKESHPL YNKVRTGQVPNCAVPCYQPSFSPDERTFATFWIGLWSVLCFISTSTTVATFLIDMERFRY PERPIIFLSACYLCVSLGFLVRLVVGHASVACSREHSHIHYETTGPALCTVVFLLVYFFG MASSIWWVILSLTWFLAAGMKWGNEAIAGYAQYFHLAAWLIPSVKSITALALSSVDGDPV AGVCYVGNQNLNSLRGFVLGPLVLYLLVGTLFLLAGFVSLFRIRSVIKQGGTKTDKLEKL MIRIGIFTLLYTVPASIVVACYLYEQHYRESWEAALTCACPGSDAGQPRAKPEYWVLMLK YFMCLVVGITSGVWIWSGKTLESWRRFTSRCCCSSRRGHKSGGAMVAGDYAEASAALTGR TGPPGPAAAYHKQVSLSHV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for Wnt proteins. Can activate WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 (in vitro); the in vivo situation may be different since not all of these are known to be coexpressed. In neurons, activation of WNT7A promotes formation of synapses. Functions in the canonical Wnt/beta-catenin signaling pathway. The canonical Wnt/beta-catenin signaling pathway leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues (Probable). Plays a role in yolk sac angiogenesis and in placental vascularization.
  • 基因功能參考文獻:
    1. MicroRNA-216b was overexposed in diabetic myocardial microvascular endothelial cells and its downregulation may actively enhance angiogenesis in diabetic angiopathy through inverse regulation on FZD5. PMID: 29477872
    2. Fzd5 has a role in the establishment of neuronal polarity, and in the morphogenesis of neuronal processes PMID: 24205342
    3. WNT7A can specifically act via a Frizzled-5.LRP6 receptor complex in PC12 cells and that this activity can be antagonized by PMID: 12857724
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell junction, synapse. Perikaryon. Cell projection, dendrite. Cell projection, axon.
  • 蛋白家族:
    G-protein coupled receptor Fz/Smo family
  • 數據庫鏈接:

    KEGG: rno:317674

    UniGene: Rn.24792



主站蜘蛛池模板: 免费人成在线观看网站| 欧美成人精品午夜免费影视| 国产成av人片在线观看无码| 亚洲欧洲中文日韩久久av乱码 | 国产成人综合在线视频| 成 人 色 网 站免费观看| 青草影院内射中出高潮| 亚洲欧洲自偷自拍图片| 久久精品国产成人午夜福利| 内射爽无广熟女亚洲| 鲁丝一区二区三区免费| av无码久久久久久不卡网站| 国产成人综合色视频精品| 久久久亚洲精品av无码| 99精品国产综合久久久久五月天 | 国产片免费福利片永久| 熟妇人妻午夜寂寞影院| 欧美尺码专线欧洲b1b1| 日本午夜看x费免| 精品一品国产午夜福利视频| 男女后式激烈动态图片| 久久久免费精品re6| 国产情侣疯狂作爱系列| 国产新婚夫妇叫床声不断| 搡老岳熟女国产熟妇| 99精品视频在线观看婷婷| 综合欧美日韩国产成人| 天堂网在线观看| 无码少妇精品一区二区免费| 99久久精品精品6精品精品| 天堂av色综合久久天堂| 国产精品原创av片国产日韩| 国产精品无码无需播放器| 国产白嫩护士在线播放| 三级网站视频在在线播放| 业余 自由 性别 成熟偷窥| 日本人妻伦在线中文字幕| 狠狠色噜噜狠狠狠狠蜜桃| 国产无遮挡又黄又爽免费视频 | 99在线精品免费视频九九视| 国产精品高潮露脸在线观看|