在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Protein Mpv17 (Mpv17)

  • 中文名稱:
    小鼠Mpv17重組蛋白
  • 貨號:
    CSB-CF014771MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Mpv17
  • Uniprot No.:
  • 別名:
    Mpv17; Protein Mpv17; Mpv-17
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-176
  • 氨基酸序列
    MALWRAYQRALAAHPWKVQVLTAGSLMGVGDMISQQLVERRGLQQHQAGRTLTMVSLGCG FVGPVVGGWYKVLDHLIPGTTKVHALKKMLLDQGGFAPCFLGCFLPLVGILNGMSAQDNW AKLKRDYPDALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAIVWNSYLSWKAHQF
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Non-selective channel that modulates the membrane potential under normal conditions and oxidative stress, and is involved in mitochondrial homeostasis. Involved in mitochondrial deoxynucleoside triphosphates (dNTP) pool homeostasis and mitochondrial DNA (mtDNA) maintenance. May be involved in the regulation of reactive oxygen species metabolism and the control of oxidative phosphorylation (Probable).
  • 基因功能參考文獻:
    1. Data show that elevated rGMP incorporation is associated with early-onset mtDNA depletion in liver and late-onset multiple deletions in brain of Mpv17-/- mice, suggesting aberrant ribonucleotide incorporation is a primary mtDNA abnormality that can result in pathology. PMID: 29106596
    2. changes in the expression of factors involved in mitochondrial deoxynucleotide homeostasis indicate a remodeling of nucleotide metabolism in MPV17 disease models PMID: 26760297
    3. the nuclear gene MPV17, whose mutated forms are associated with hepatocerebral MDDS in humans, plays a so-far unknown role in mtDNA maintenance PMID: 25205723
    4. the inner mitochondrial membrane protein Mpv17 in podocytes is essential for the maintenance of mitochondrial homeostasis and protects podocytes against oxidative stress-induced injury both in vitro and in vivo. PMID: 24598802
    5. A lack of Mpv17 protein function in mitochondria thus seems to initiate tissue-specific cell-death pathways resulting in the pathology seen during the degeneration process. PMID: 22322422
    6. Data suggest that Rhit acts as a repressor in the heat-induced and age-dependent transcriptional regulation of the (S) isoform of Mpv17-like protein. PMID: 20231359
    7. the functions of certain M-LP isoforms are tissue- and species-specific, implying that their potential involvement in Reactive Oxygen Species metabolism may be redundant or may be complemented by other members of the Mpv17 family. PMID: 19935920
    8. These results show the existence of the human homolog of M-LP and its participation in reactive oxygen species metabolism. PMID: 16631601
    9. Severe mtDNA depletion in liver in Mpv17 knockout mice; these results demonstrate that Mpv17 controls mtDNA copy number by a highly tissue- and possibly cytotype-specific mechanism. PMID: 18818194

    顯示更多

    收起更多

  • 亞細胞定位:
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Peroxisomal membrane protein PXMP2/4 family
  • 組織特異性:
    High levels in heart, kidney, and brain, intermediate levels in testis, and low levels in liver and spleen.
  • 數據庫鏈接:


主站蜘蛛池模板: 2021麻豆剧传媒一二三区| 天堂√在线中文最新版| 天堂av无码大芭蕉伊人av不卡| 日本工口里番无遮█彩色| 国产做a爰片久久毛片a片美国| 亚洲精品国产精品乱码不卡√| 亚洲国产av精品一区二区蜜芽| 男人扒开女人腿桶到爽免费| 999zyz玖玖资源站永久| 成人视频在线观看| 亚洲精品福利一区二区三区蜜桃| 久久婷婷国产剧情内射白浆| 久久天天躁狠狠躁夜夜2020老熟妇| 亚洲欧美色中文字幕在线| 国产免费又爽又色又粗视频| 亚洲色欲久久久久综合网| 四虎永久在线高清国产精品| 动漫成人无码精品一区二区三区| 色噜噜噜亚洲男人的天堂| 1000部夫妻午夜免费| 中文字幕日韩欧美一区二区三区| 人人色在线视频播放| 少妇人妻上班偷人精品视频| 美女被啪到深处抽搐视频| 欧美乱码卡一卡二卡三新区| 久久综合九色综合网站| 99麻豆久久久国产精品免费 | 亚洲伊人色综合www962| 狠狠做五月深爱婷婷伊人| 乱子伦视频在线看| 国产网红主播无码精品| 麻豆国产在线精品国偷产拍| 免费大片av手机看片不卡| 黄瓜视频在线观看网址| 国产对白老熟女正在播放| 国产精品一区二区av| 久久久久 亚洲 无码 av 专区| 成 人影片 aⅴ毛片免费观看| 久久综合狠狠综合久久综合88| 苍井空亚洲精品aa片在线播放| 国产无套粉嫩白浆在线|