在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Prostacyclin synthase (Ptgis)

  • 中文名稱:
    小鼠Ptgis重組蛋白
  • 貨號:
    CSB-CF018982MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Ptgis
  • Uniprot No.:
  • 別名:
    Ptgis; Cyp8; Prostacyclin synthase; Hydroperoxy icosatetraenoate dehydratase; Prostaglandin I2 synthase
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區(qū)域:
    1-501
  • 氨基酸序列
    MSWAALLGLLAVLLLLLLLLSRRRARRPGEPPLDLGSIPWLGHALEFGRDAASFLTRMKEKHGDIFTVLVGGRYVTVLLDPHSYDTVVWELRTRLDFHPYAIFLMERIFDLQLPNFNPSEEKARMKPTLMHRDLQALTEAMYTNLRTVLLGDSTEAGSGWQETGLLEFSYNALLSAGYLTLYGVEASPRTHESQAQDRVHSADVFHTFRQLDLLLPKLARGSLSAGDKDHACSVKNRLWKLLSPARLASRADRSSWLESYLRHLEEMGVSEEMQARALVLQLWATQGNMGPTAFWLLLFLLKNPEALAAVRAELKHTVWQAEQPVSQMTTLPQKILDSMPVLDSVLNETLRLTAAPFITREVMADLALPMADGREFSLRRGDRLLLFPFLSPQKDPEIYTEPEVFKYNRFLNPDGSEKKDFYKDGKRLKNYNMPWGAGHNQCLGKSYAINSIKQFVVLLLTHFDLELGSEDTEVPEFDLSRYGFGLMQPEEDVPIRYRARL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE).
  • 基因功能參考文獻:
    1. Prostacyclin synthase and prostaglandin E synthase-1 cooperatively exacerbate inflammatory reactions but have opposing effects on carcinogenesis. PMID: 26611322
    2. Taken together, our in vitro and in vivo findings show that prostacyclin is secreted from neovessels formed as a result of CNS inflammation PMID: 23042236
    3. Cyclooxygenase-2-derived prostacyclin regulates arterial thrombus formation by suppressing tissue factor in a sirtuin-1-dependent-manner. PMID: 22865892
    4. Gene transfer of thromboxane A(2) synthase and prostaglandin I(2) synthase antithetically altered tumor angiogenesis and tumor growth. PMID: 11782360
    5. an anlysis of the transcription regulation of this gene PMID: 12664598
    6. The two major genetic loci Pgis1 and Pgis2 of murine spondylitis are homologous to chromosome regions in human genome, which control ankylosing spondylitis in human patients. PMID: 16081819
    7. CD40 ligand might contribute to the initiation and progression of atherosclerosis by increasing activity of prostacyclin synthase. PMID: 16186418
    8. Alpha(2)-adrenoreceptor activation is required for coupling heart rate to central inspiratory drive during acute hypoxia, and PGI(2) is required to enhance the inhibition of sympathoactivation. PMID: 17120018
    9. The results provide strong evidence that the protective effects of COX-2 within the liver are mediated through the production of PGE(2) and PGI(2), which exert anti-inflammatory functions. PMID: 17187424
    10. Endothelial PGI synthase-mediated prostacyclin contributes to renal protection against endotoxemia-related acute kidney injury. PMID: 17652370
    11. COX-1 contributes to the enhanced formation of both PGI(2) and TXA(2) in atherosclerosis, and to the development of the disease PMID: 18514659
    12. The results establish a role for the IP receptor in protecting pyramidal hippocampal neurons after this global ischemic model and suggest that IP receptor agonists could be developed to prevent delayed pyramidal neuronal cell death. PMID: 18790018

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Single-pass membrane protein.
  • 蛋白家族:
    Cytochrome P450 family
  • 數(shù)據(jù)庫鏈接:

    KEGG: mmu:19223

    STRING: 10090.ENSMUSP00000018113

    UniGene: Mm.2339



主站蜘蛛池模板: 国产在线播放精品视频| 美女扒开尿口让男人桶| 精品麻豆国产色欲色欲色欲www| 精品亚洲成a人片在线观看| 男ji大巴进入女人的直播| 天堂а√8在线最新版在线| 日本精品少妇一区二区三区| 性色欲情网站iwww| 18禁无遮挡羞羞污污污污免费| 亚洲男人的天堂在线aⅴ视频| 中文人妻熟女乱又乱精品| 欧洲熟妇性色黄| 日韩新无码精品毛片| 秋霞在线观看片无码免费不卡| 国产曰批免费视频播放免费| 最新高清无码专区| 放荡的美妇在线播放| 99精品国产福利在线观看| 欧洲丰满大乳人妻无码欧美| 欧美真人做爰在线观看| 久久久久99精品成人片直播| 国产超碰人人爱被ios解锁| 日韩精品亚洲人旧成在线| 亚洲卡一卡二乱码新区仙踪| 无遮挡又黄又刺激的视频| 性生交大片免费看l| 一色屋精品视频在线观看免费| 精品日产一卡2卡三卡4卡在线| 国产精品露脸国语对白| 忘忧草社区中文字幕www| 成人无码α片在线观看不卡| 国产无套露脸在线观看| 亚洲精品成人久久久| 国产成人片无码免费视频| 午夜嘿嘿嘿在线观看| 人妻少妇偷人精品视频| 国产绳艺sm调教室论坛 | 亚洲日韩v无码中文字幕| 无码h肉在线观看免费一区| 韩国国内大量揄拍精品视频 | 亚洲xxxx做受欧美|