在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Prokineticin receptor 1 (Prokr1)

  • 中文名稱:
    小鼠Prokr1重組蛋白
  • 貨號:
    CSB-CF018748MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Prokr1; Gpr73; Pkr1; Prokineticin receptor 1; PK-R1; G-protein coupled receptor 73
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-393
  • 氨基酸序列
    METTVGALGENTTDTFTDFFSALDGHEAQTGSLPFTFSYGDYDMPLDEEEDVTNSRTFFA AKIVIGMALVGIMLVCGIGNFIFITALARYKKLRNLTNLLIANLAISDFLVAIVCCPFEM DYYVVRQLSWEHGHVLCASVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLRPRMKCQTAA GLIFLVWSVSILIAIPAAYFTTETVLVIVERQEKIFCGQIWPVDQQFYYRSYFLLVFGLE FVGPVVAMTLCYARVSRELWFKAVPGFQTEQIRRRLRCRRRTVLGLVCVLSAYVLCWAPF YGFTIVRDFFPSVFVKEKHYLTAFYVVECIAMSNSMINTLCFVTVRNNTSKYLKRILRLQ WRASPSGSKASADLDLRTTGIPATEEVDCIRLK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for prokineticin 1. Exclusively coupled to the G(q) subclass of heteromeric G proteins. Activation leads to mobilization of calcium, stimulation of phosphoinositide turnover and activation of p44/p42 mitogen-activated protein kinase. May play a role during early pregnancy.
  • 基因功能參考文獻:
    1. The authors discovered that PKR1 regulates epicardial-mesenchymal transition (EMT) for epicardial-derived progenitor cell (EPDC), formation. This event affects at least three consequential steps during heart development: (i) EPDC and cardiomyocyte proliferation involved in thickening of an outer compact ventricular chamber wall, (ii) rhythmicity, (iii) formation of coronary circulation. PMID: 27150455
    2. These results establish PKR1 via NFATc3 as a crucial modifier of mesenchymal-epithelial transition processing to the development of nephron. PMID: 27084889
    3. show that MRAP2 significantly and specifically inhibits PKR1 signaling. PMID: 26829592
    4. These results suggest PKR1 to be a crucial player in the preadipocyte proliferation and differentiation. PMID: 24324673
    5. Loss of PKR1 causes renal and cardiac structural and functional changes because of deficits in survival signaling, mitochondrial, and progenitor cell functions in found both organs. PMID: 21273561
    6. The functional characteristics of coronary endothelial cells depend on the expression of PKR1 and PKR2 levels and the divergent signaling pathways used by these receptors. PMID: 20023120
    7. Identification and molecular characterization of two closely related G protein-coupled receptors (prokineticin receptor) PMID: 11886876
    8. PKR1 protein was localised to the labyrinth layer and showed the same pattern of expression as EG-VEGF in mouse placenta. PMID: 17531315

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 組織特異性:
    Expressed at high levels in the heart, skeletal muscle and pancreas. Expressed at lower levels in the brain, lung, liver and kidney.
  • 數據庫鏈接:


主站蜘蛛池模板: 日韩在线看片免费人成视频播放| 国产一区二区三区精品视频| 国产精品中文久久久久久久| 国产精品午夜无码av体验区| 极品少妇xxxx| 国产内射合集颜射| 丁香五月激情综合色婷婷| 国产特级毛片aaaaaa| 四虎永久免费地址入口| 伊人久久丁香色婷婷啪啪| 色综合a怡红院怡红院| 国产精品va在线播放| 久久久亚洲精品成人| 精品无码人妻一区二区三区不卡| 国产精品成人无码久久久| 久热在线这里只有精品国产| 五月丁香六月综合缴情在线| 2020精品国产a不卡片| 夜夜躁很很躁日日躁麻豆 | 99久久国产精品免费高潮| 97无码精品综合| 亚洲精品中文字幕乱码4区| 久久久久国产精品熟女影院| 全黄性性激高免费视频| 久久精品国产自在天天线| 国产精品嫩草影院免费观看| 亚洲无碼网站观看| 日本精品人妻无码免费大全| 无码人妻av一二区二区三区| 欧美日韩免费专区在线| 成在人线av无码免费看网站直播| 女人喷潮完整视频| 国模叶桐尿喷337p人体| 无码av最新无码av专区| 100禁毛片免费40分钟视频| 亚洲中文在线精品国产| 香港aa三级久久三级| 朝鲜女人大白屁股ass| 亚洲精品一区二区不卡| 嫖妓大龄熟妇正在播放| 天天躁日日躁狠狠躁免费麻豆|