在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 跨膜蛋白
  4. Recombinant Mouse Presenilins-associated rhomboid-like protein, mitochondrial (Parl)

Recombinant Mouse Presenilins-associated rhomboid-like protein, mitochondrial (Parl)

  • 中文名稱：
    小鼠Parl重組蛋白
  • 貨號(hào)：
    CSB-CF733431MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    Parl
  • Uniprot No.：
  • 別名：
    Parl; Psarl; Presenilins-associated rhomboid-like protein, mitochondrial; Mitochondrial intramembrane-cleaving protease PARL
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    51-377
  • 氨基酸序列
    FRKAPRKVEPRRSDTGSSGEAYKRSALIPPLEETVFYPSPYPIRTLVKPFFFTIGFTGCA FGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQKEGNLRKEINKWWNSLSDGQRTVTGI IAANALVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSF SSSIVNILGQEQFVAVYLSAGVISNFVSYVCKVATGRYGPSLGASGAIMTVLAAVCTKIP EGRLAIIFLPVFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYITYGHEL IWKNREPLVKIWHEIRTNGPKKGGGSK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptotic signals. Required for the maturation of PINK1 into its 52kDa mature form after its cleavage by mitochondrial-processing peptidase (MPP). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.
  • 基因功能參考文獻(xiàn)：
    1. Downregulation of PARL after ischemia is a key step in ischemic neuronal injury, and that it decreases HtrA2 processing and increases neuronal vulnerability. PMID: 23921894
    2. Suppression of PARL protein in healthy myotubes lowered mitochondrial mass and insulin-stimulated glycogen synthesis and increased reactive oxygen species production. PMID: 20444421
    3. results indicate a different function and mechanism of Hax1 in apoptosis and re-opens the question of whether mammalian PARL, in addition to apoptosis, regulates mitochondrial stress response through Omi/HtrA2 processing. PMID: 19680265
    4. Parl-/- mitochondria display reduced levels of OPA1, and OPA1 specifically targeted to IMS complements Parl-/- cells, substantiating the importance of PARL in OPA1 processing.(PARL protein, mouse) PMID: 16839884
    5. Hax1, is required to suppress apoptosis in lymphocytes and neurons; suppression requires the interaction of Hax1 with the mitochondrial proteases Parl and HtrA2 PMID: 18288109

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.; [P-beta]: Nucleus.
  • 蛋白家族：
    Peptidase S54 family
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 欧美天天综合色影久久精品| 国产精品亚洲精品一区二区| 久久毛片免费看一区二区三区 | 午夜视频久久久久一区| 免费国产成人高清在线观看网站| 一区二三区在线 | 中国| 日本亚洲欧洲无免费码在线| 久久av高潮av无码av喷吹| 亚洲欧美乱日韩乱国产| av在线亚洲男人的天堂| 国产主播av福利精品一区| 亚洲欧美不卡视频在线播放 | 国产超碰无码最新上传| 人妻丰满av无码中文字幕| 日韩免费无码专区精品观看| 污污内射久久一区二区欧美日韩| 老熟妻内射精品一区| 久久天天躁狠狠躁夜夜夜| 欧美人与动牲交免费观看| 特黄大片又粗又大又暴| 一二三四视频社区在线播放中国| 久久中文字幕无码a片不卡古代| 亚洲男人的天堂一区二区| 亚洲中久无码永久在线观看同 | 日日鲁鲁鲁夜夜爽爽狠狠| 久久久久久人妻毛片a片| 97久久精品人人槡人妻人| 日日噜噜噜噜夜夜爽亚洲精品| 奇米影视777四色狠狠| 麻豆精产一二三产区| 综合 欧美 小说 另类 图| 国产又粗又猛又黄又爽无遮挡| 88国产精品欧美一区二区三区| 日韩人妻无码精品久久| 亚洲最大av网站在线观看| 18禁裸男晨勃露j毛免费观看 | 中国熟妇毛多多裸交视频| 国产午夜成人免费看片app | 特黄特色的大片观看免费视频| 丰满日韩放荡少妇无码视频| 久久久中日ab精品综合|