在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Gamma-sarcoglycan (Sgcg)

  • 中文名稱:
    小鼠Sgcg重組蛋白
  • 貨號:
    CSB-CF021186MO
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    Sgcg
  • Uniprot No.:
  • 別名:
    Sgcg; Gamma-sarcoglycan; Gamma-SG; 35 kDa dystrophin-associated glycoprotein; 35DAG
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-291
  • 氨基酸序列
    MVREQYTTVTEGTHIERPENQHIYKIGIYGWRKRCLYLFVLLLLAILVVNLALTIWILKVMWFSPIGMGHLHVTADGLRLEGESEFLFPLYAKEIRSRVDSSLLLQSTQNVTVSARNSEGEVTGRVKVGAQMVEVQSQHFQINSEDGKPLFSAEEQDVVVGTGRLRVTGPEGALFEHSVETPLVRADPFQDLRLESPTRSLSMDAPRGVHVKANAGKLEALSQMDIILQSSEGVLVLDAETVGLTKLKQGTQGPAGSSNGFYEICACPDGKLYLSMAGEVTTCEEHSHVCL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
  • 基因功能參考文獻:
    1. Cleavage of beta-DG still occurred when both MMP-2 and MMP-9 were knocked out in gamma - sarcoglycan-deficient mice. The study found that up-regulation of MMP-14 is capable of cleaving beta-DG, and it may be involved in the pathogenesis of sarcoglycanopathy. PMID: 28821434
    2. for MD research. The Sgcg(-/-) mice have a more severe phenotype than the mdx mice. Muscle function was assessed by plethysmography and echocardiography. Histologically the Sgcg(-/-) mice displayed increased fibrosis and variable fiber size. PMID: 26064876
    3. These results position archvillin as a mechanically sensitive component of the dystrophin complex and demonstrate that signaling defects caused by loss of gamma-SG occur both at the sarcolemma and in the nucleus. PMID: 25605665
    4. localization of gamma-SG does not require Tyr(6), but localization alone is insufficient for restoration of normal signal transduction patterns after mechanical perturbation PMID: 20371873
    5. The limb, shoulder, and pelvic muscles of the gsg-/- mice exhibited progressive muscle hypertrophy and weakness with age, and the findings were similar to those seen in other mouse models for limb-girdle and Duchenne muscular dystrophy. PMID: 12609501
    6. In sarcoglycan mutant mice, regionally increased cardiac NO was associated with hypersensitivity to carbachol and decreased sensitivity to adrenergic stimulation. PMID: 14871549
    7. sarcoglycan and integrin alpha7beta1 have overlapping roles in mediating cytoskeletal-membrane-extracellular matrix interaction PMID: 15252120
    8. Sarcoglycan gamma missense mutations affect sarcoglycan complex assembly and/or localization to the cell surface and provide information on the molecular mechanisms underlying the effects of various sarcoglycan mutations in muscular dystrophies. PMID: 16524571

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane, sarcolemma; Single-pass type II membrane protein. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Sarcoglycan beta/delta/gamma/zeta family
  • 組織特異性:
    Most strongly expressed in skeletal and heart muscle. Also detected in proliferating myoblasts.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲精品喷潮一区二区三区| 日日摸天天摸人人看| 亚洲精品国产一区二区三| 中文字幕人妻第一区| 纯爱无遮挡h肉动漫在线播放| 中文字幕精品亚洲无线码二区| 99久久精品日本一区二区免费| 日产无码中文字幕av| 美女裸奶100%无遮挡免费网站| 东京热大乱系列无码| 天天爽夜夜爽人人爽| 日本成aⅴ人片日本伦| 久久99精品国产99久久6尤物| 国产欧美va天堂在线电影| 国产成人无码a区在线观看视频免费| 亚洲熟妇无码av| 亚洲精品久久久久久无码色欲四季| 黑人上司粗大拔不出来电影| 中文资源在线天堂库8| 丰满少妇被猛烈进入试看| 亚洲精品一线二线三线无人区| 国产超碰人人爽人人做| 手机看片国产av无码| 国产亚洲精品福利视频| 久久久国产精品麻豆a片| 精品午夜福利1000在线观看| 久久午夜无码鲁丝片秋霞| 日韩亚洲国产综合高清| 亚洲欧美不卡视频在线播放| 亚洲人成无码网站久久99热国产| 亚洲色婷婷六月亚洲婷婷6月| 国产人妻精品区一区二区三区| 亚洲精品少妇一区二区| 免费观看全黄做爰大片国产| 精久国产av一区二区三区孕妇| s级爆乳玩具酱国产vip皮裤| 精品国产乱码久久久软件下载| 欧美午夜刺激影院| 无码一区二区三区av免费| 国产蜜芽尤物在线一区| 伊人久久大香线蕉无码不卡|