在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Potassium channel subfamily K member 16 (KCNK16)

  • 中文名稱:
    人KCNK16重組蛋白
  • 貨號:
    CSB-CF850434HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    KCNK16
  • Uniprot No.:
  • 別名:
    KCNK16; TALK1; Potassium channel subfamily K member 16; 2P domain potassium channel Talk-1; TWIK-related alkaline pH-activated K(+ channel 1; TALK-1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-309
  • 氨基酸序列
    MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF PISKKGLGS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.
  • 基因功能參考文獻:
    1. data establish TALK-1 channels as key regulators of beta cell ER Ca(2+) and suggest that TALK-1 may be a therapeutic target to reduce ER Ca(2+) handling defects in beta cells during the pathogenesis of diabetes. PMID: 28928238
    2. The TALK-1/iOPN complex caused Vm hyperpolarization and reduced beta-cell glucose-stimulated Ca2+ influx, which is predicted to inhibit glucose stimulated insulin secretion. PMID: 28403169
    3. These findings reveal TALK-1 channels as important modulators of second-phase insulin secretion and suggest a clinically relevant mechanism for rs1535500, which may increase type 2 diabetes risk by limiting glucose-stimulated insulin secretion. PMID: 26239056
    4. at least two functional TALK-1 variants are present and may serve as background K+ currents in certain cells of the human pancreas. PMID: 12724142
  • 亞細胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Two pore domain potassium channel (TC 1.A.1.8) family
  • 組織特異性:
    Highly expressed in pancreas. Not detectable in the other tissues tested.
  • 數據庫鏈接:

    HGNC: 14464

    OMIM: 607369

    KEGG: hsa:83795

    STRING: 9606.ENSP00000391498

    UniGene: Hs.287765



主站蜘蛛池模板: 国产精品无套呻吟在线| 亚洲男人成人性天堂网站| 99精品国产福久久久久久| 野外少妇愉情中文字幕| 欧美巨大黑人极品精男| 天天爽亚洲中文字幕| 中文无码精品a∨在线| 免费精品99久久国产综合精品| 伊人久久大香线蕉av一区| 真实国产乱子伦视频| 国产免费久久精品99reswag| 久久久久久久久蜜桃| 亚洲成av人片在线观看无码不卡 | 亚洲国产精品久久精品| 亚洲成色在线综合网站| 亚洲精品无码久久久影院相关影片| 都市激综合小说区另类区| 欧美肥胖老妇bbw| 无码av免费永久免费永久专区| 欧美人与动牲交欧美精品| 久久久久成人精品无码中文字幕| 97se亚洲精品一区| 精品玖玖玖视频在线观看| 国产草莓视频无码a在线观看| 久久人人爽人人爽人人片av高清| 欧洲熟妇牲交| 九色综合九色综合色鬼| 日韩免费无码专区精品观看 | 动漫av永久无码精品每日更新| 亚洲性夜色噜噜噜在线观看不卡| 人妻少妇中文字幕乱码| 久青草无码视频在线观看| 久久精品亚洲精品无码白云tv| 日本va在线视频播放| 暖暖 在线 日本 免费 中文| 国产情侣激情在线视频| 朝鲜女子内射杂交bbw| 亚洲人亚洲精品成人网站| 国产亚洲精品久久yy5099| 亚洲天天做日日做天天欢毛片| 欧美s码亚洲码精品m码|