在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Parathyroid hormone 2 receptor (PTH2R)

  • 中文名稱:
    人PTH2R重組蛋白
  • 貨號:
    CSB-CF018990HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Parathyroid hormone 2 receptor; Parathyroid hormone receptor precursor ; PTH 2 receptor ; PTH2 receptor; Pth2r; PTH2R_HUMAN; Pthr 2; Pthr2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    27-145
  • 氨基酸序列
    DSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPC PPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    10xHis-SUMO-tag
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.
  • 基因功能參考文獻:
    1. expressed in the epidermis in Darier disease PMID: 28094886
    2. PTH2R and its ligand TIP39 regulate intracellular calcium and influence keratinocyte differentiation PMID: 27000502
    3. Authors report PTH2R as a gene that is disrupted in NSC. The disruption of the PTH2R gene may cause uncontrolled proliferation and differentiation of chondrocytes. PMID: 26044810
    4. Variation in the PTH2R gene (Chr2q34, rs897083) may contribute to the age-associated degenerative manifestations that develop at the lumbar spine PMID: 24378925
    5. Data suggest role for PTH2R signaling in postnatal growth plate development and subsequent bone mass acquisition; overexpression of human PTH2R in chondrocytes of transgenic mice has key consequences on postnatal development of endochondral skeleton. PMID: 23092913
    6. specific interactions within the ligand-receptor bimolecular complex mediate distinct postactivation responses of class II G protein- coupled receptors and provide novel insights into the physiological regulation of PTH2R activity PMID: 14988434
    7. The distribution of PTH2R-immunoreactive fibers in viscerosensory brain regions is similar to that reported in mouse and rat suggesting a similar role of the PTH2R in human as in rodents. PMID: 18459453
    8. The results demonstrate that TIP39 and the PTH2R are expressed in the brain of primates in locations that suggest involvement in regulation of fear, anxiety, reproductive behaviors, release of pituitary hormones, and nociception. PMID: 19401215

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 2 family
  • 組織特異性:
    Expressed abundantly in brain and pancreas. Also expressed in the testis.
  • 數據庫鏈接:

    HGNC: 9609

    OMIM: 601469

    KEGG: hsa:5746

    STRING: 9606.ENSP00000272847

    UniGene: Hs.570296



主站蜘蛛池模板: 日韩精品一区二区三区vr| 无码国产精品成人| 久久无码高潮喷水| 无码国产精品一区二区免费模式| 国产精品无码久久久久久久久久| 国产精品福利视频萌白酱| 国产真实偷乱视频| 麻豆精品偷拍人妻在线网址| 亚洲欧美综合在线天堂| 久久精品国产99精品国产2021| 成人欧美一区二区三区1314| 99热门精品一区二区三区无码| 色偷偷人人澡久久超碰97| 高潮潮喷奶水飞溅视频无码 | 天天鲁一鲁摸一摸爽一爽| 四虎亚洲中文字幕无码永久 | 久久不见久久见免费影院www | 精品无码av一区二区三区不卡| 女人被狂躁c到高潮喷水一区二区| 揉捏奶头高潮呻吟视频| 亚洲精品色播一区二区| 熟妇激情内射com| 巨大欧美黑人xxxxbbbb| 欧洲熟妇色xxxx欧美老妇多毛网站| 精品无人区一区二区三区在线| 国产360激情盗摄全集| 少妇人妻偷人激情视频| 欧美性生 活18~19| 亚洲精品久久久久高潮| 无码国产精成人午夜视频| 久久婷婷成人综合色综合| 亚洲欧美国产精品久久久久久久| 国产寡妇偷人在线观看| 曰韩a∨无码一区二区三区| 久久亚洲精品无码va白人极品 | 变态 另类 欧美 大码 日韩| 人妻无码vs中文字幕久久av爆| 色诱久久久久综合网ywww| 51国偷自产一区二区三区| 男人撕开奶罩揉吮奶头视频| 18禁美女黄网站色大片免费网站 |