在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Parathyroid hormone 2 receptor (PTH2R)

  • 中文名稱:
    人PTH2R重組蛋白
  • 貨號:
    CSB-CF018990HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    Parathyroid hormone 2 receptor; Parathyroid hormone receptor precursor ; PTH 2 receptor ; PTH2 receptor; Pth2r; PTH2R_HUMAN; Pthr 2; Pthr2
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    27-145
  • 氨基酸序列
    DSDGTITIEEQIVLVLKAKVQCELNITAQLQEGEGNCFPEWDGLICWPRGTVGKISAVPC PPYIYDFNHKGVAFRHCNPNGTWDFMHSLNKTWANYSDCLRFLQPDISIGKQEFFERLY
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    10xHis-SUMO-tag
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor.
  • 基因功能參考文獻:
    1. expressed in the epidermis in Darier disease PMID: 28094886
    2. PTH2R and its ligand TIP39 regulate intracellular calcium and influence keratinocyte differentiation PMID: 27000502
    3. Authors report PTH2R as a gene that is disrupted in NSC. The disruption of the PTH2R gene may cause uncontrolled proliferation and differentiation of chondrocytes. PMID: 26044810
    4. Variation in the PTH2R gene (Chr2q34, rs897083) may contribute to the age-associated degenerative manifestations that develop at the lumbar spine PMID: 24378925
    5. Data suggest role for PTH2R signaling in postnatal growth plate development and subsequent bone mass acquisition; overexpression of human PTH2R in chondrocytes of transgenic mice has key consequences on postnatal development of endochondral skeleton. PMID: 23092913
    6. specific interactions within the ligand-receptor bimolecular complex mediate distinct postactivation responses of class II G protein- coupled receptors and provide novel insights into the physiological regulation of PTH2R activity PMID: 14988434
    7. The distribution of PTH2R-immunoreactive fibers in viscerosensory brain regions is similar to that reported in mouse and rat suggesting a similar role of the PTH2R in human as in rodents. PMID: 18459453
    8. The results demonstrate that TIP39 and the PTH2R are expressed in the brain of primates in locations that suggest involvement in regulation of fear, anxiety, reproductive behaviors, release of pituitary hormones, and nociception. PMID: 19401215

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族:
    G-protein coupled receptor 2 family
  • 組織特異性:
    Expressed abundantly in brain and pancreas. Also expressed in the testis.
  • 數據庫鏈接:

    HGNC: 9609

    OMIM: 601469

    KEGG: hsa:5746

    STRING: 9606.ENSP00000272847

    UniGene: Hs.570296



主站蜘蛛池模板: 国产欧美日韩国产高清| 欧美性猛交xxxx乱大交蜜桃| 久久久久亚洲精品中文字幕| 亚洲国产一区二区三区波多野结衣| 999久久久国产精品消防器材| 精品亚洲国产成av人片传媒| 国产在线拍揄自揄视频网试看| 国产美女遭强高潮网站下载| 久久综合久色欧美综合狠狠| 亚洲性无码av在线欣赏网| 亚洲另类成人小说综合网| 77se77亚洲欧美在线| 国产末成年女av片一区二区| 中文字幕高清免费日韩视频在线| 欧美亚洲一区二区三区| 天天爱天天做天天做天天吃中文| av无码人妻波多野结衣| 欧美亚洲日本高清不卡| 性高湖久久久久久久久aaaaa| 亚洲国产成人久久综合碰| 成人a片产无码免费视频在线观看| 精品亚洲aⅴ无码一区二区三区| 搡老熟女老女人一区二区| 成人做爰100部片免费下载| 国产精品国产三级在线... | 男人的天堂av社区在线| 免费国产线观看免费观看| 四川丰满妇女毛片四川话| 中文日韩亚洲欧美制服| 国产清纯美女遭强到高潮| 亚洲精品国产第一综合99久久| 欧美三级不卡在线观看| av高清无码 在线播放| 成人做爰www网站视频下载| 裸身美女无遮挡永久免费视频| 久久久久噜噜噜亚洲熟女综合| 18禁真人抽搐一进一出在线| 性色欲情网站iwww九文堂| 十八禁裸体www网站免费观看| 最新永久无码av网址亚洲| 无人去码一码二码三码区|