在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Metalloreductase STEAP1 (STEAP1)

Unavailable
  • 中文名稱:
    人STEAP1重組蛋白
  • 貨號:
    CSB-CF890691HU
  • 規格:
    ¥9720
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    STEAP1; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length
  • 來源:
    in vitro E.coli expression system
  • 分子量:
    58.4kDa
  • 表達區域:
    1-339aa
  • 氨基酸序列
    MESRKDITNQEELWKMKPRRNLEEDDYLHKDTGETSMLKRPVLLHLHQTAHADEFDCPSELQHTQELFPQWHLPIKIAAIIASLTFLYTLLREVIHPLATSHQQYFYKIPILVINKVLPMVSITLLALVYLPGVIAAIVQLHNGTKYKKFPHWLDKWMLTRKQFGLLSFFFAVLHAIYSLSYPMRRSYRYKLLNWAYQQVQQNKEDAWIEHDVWRMEIYVSLGIVGLAILALLAVTSIPSVSDSLTWREFHYIQSKLGIVSLLLGTIHALIFAWNKWIDIKQFVWYTPPTFMIAVFLPIVVLIFKSILFLPCLRKKILKIRHGWEDVTKINKTEICSQL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-SUMO-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.
  • 基因功能參考文獻:
    1. High STEAP1 expression is associated with prostate cancer. PMID: 29464393
    2. Data suggest a solid basis for further research into understanding how six-transmembrane epithelial antigen of prostate member 1 (STEAP1) activities may affect cancer progression. PMID: 27792302
    3. These findings highlight the ability of immuno-PET with (89)Zr-2109A to detect acute changes in STEAP1 expression PMID: 25453051
    4. Data indicate that six transmembrane epithelial antigen of the prostate 1 (STEAP1) is consistently overexpressed in malignant prostate tissue, namely adenocarcinoma and prostatic intraepithelial neoplasia (PIN) lesions. PMID: 24239460
    5. The findings provide evidence that STEAP1 is a biomarker of worse prognosis in prostate carcinomas patients. PMID: 24025158
    6. STEAP1 is down-regulated by dihydrotestosterone and estradiols in LNCaP cells and in rat prostate. PMID: 23060075
    7. A total of 62.3% of the Ewing's Sarcoma samples displayed detectable STEAP1 expression with predominant localization of the protein at the plasma membrane. PMID: 22317770
    8. STEAP1 is associated with the invasive behavior and oxidative stress phenotype of Ewing tumors, an unanticipated oncogenic function of STEAP1. PMID: 22080479
    9. STEAP1 overexpression predicts improved outcome of Ewing's sarcoma patients, possibly due to enhanced sensitivity towards ROS-generating chemotherapeutics. PMID: 22317770
    10. EWS-FLI1 mediated overexpression of STEAP1 increases the invasiveness and oxidative stress levels of Ewing tumor cells. PMID: 22080479
    11. Data suggest that zoledronic acid may affect cancer cells also by targeting the gene expression of STEAP. PMID: 19915386
    12. Peptide STEAP-292.2L (MLAVFLPIV) may have potential as an antitumor peptide vaccine. PMID: 15958640
    13. STEAP mRNA is used here as a marker to evaluate biological samples from individuals suspected of having cancers, and may provide prognostic information useful in defining appropriate therapeutic options. PMID: 18793824
    14. STEAP1 is over-expressed in breast cancer and down-regulated by 17beta-estradiol. PMID: 18958632
    15. STEAPs may represent novel markers of mesenchymal stem cells in man as well as mice. PMID: 19196137

    顯示更多

    收起更多

  • 亞細胞定位:
    Endosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    STEAP family
  • 組織特異性:
    Ubiquitously expressed. Highly expressed in prostate tumors.
  • 數據庫鏈接:

    HGNC: 11378

    OMIM: 604415

    KEGG: hsa:26872

    STRING: 9606.ENSP00000297205

    UniGene: Hs.61635



主站蜘蛛池模板: 伊人久久精品av一区二区| 小辣椒福利视频导航| 国产精品综合一区二区三区| 日本丰满护士爆乳xxxx| 欧美另类bbbxxxxx另类| 国产色爱av资源综合区| 国内精品免费久久久久电影院| 亚洲成色在线综合网站| 免费h动漫无码网站| 丰满的少妇邻居中文bd| 国产顶级熟妇高潮xxxxx| wwww亚洲熟妇久久久久| 欧美亚洲一区二区三区| 女同亚洲一区二区无线码| 久久精品99无色码中文字幕| 午夜少妇性影院私人影院在线| 久久综合给合久久狠狠狠97色 | 日韩国产成人精品视频| 色窝窝色蝌蚪在线视频| 国产av福利久久| 日本黄网站免费| 国产精品久久久久9999赢消| av无码国产在线观看岛国| 综合色区国产亚洲另类| 亚洲另类激情综合偷自拍图| 精品人妻av一区二区三区| 成人3d动漫一区二区三区| 日本在线a一区视频| 中文字幕制服丝袜人妻动态图 | 精品欧美小视频在线观看| 潮喷失禁大喷水aⅴ无码| 亚洲午夜精品a片久久www慈禧| 精品成人免费国产片| 国产98在线 | 免费| 欧美日韩中文国产一区发布 | 日本特黄特色aaa大片免费| 亚洲乱码日产精品bd在线观看 | 亚洲精品国产品国语原创| 国产精品久久久久久影视不卡| 欧洲成人一区二区三区| 麻豆自媒体 一区 二区|