在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Integral membrane protein GPR137 (GPR137)

  • 中文名稱:
    人GPR137重組蛋白
  • 貨號(hào):
    CSB-CF856990HU
  • 說明書:
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
    GPR137
  • Uniprot No.:
  • 別名:
    GPR137; C11orf4; GPR137A; TM7SF1L1; Integral membrane protein GPR137; Transmembrane 7 superfamily member 1-like 1 protein
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-417
  • 氨基酸序列
    MESNLSGLVPAAGLVPALPPAVTLGLTAAYTTLYALLFFSVYAQLWLVLLYGHKRLSYQT VFLALCLLWAALRTTLFSFYFRDTPRANRLGPLPFWLLYCCPVCLQFFTLTLMNLYFAQV VFKAKVKRRPEMSRGLLAVRGAFVGASLLFLLVNVLCAVLSHRRRAQPWALLLVRVLVSD SLFVICALSLAACLCLVARRAPSTSIYLEAKGTSVCQAAAMGGAMVLLYASRACYNLTAL ALAPQSRLDTFDYDWYNVSDQADLVNDLGNKGYLVFGLILFVWELLPTTLLVGFFRVHRP PQDLSTSHILNGQVFASRSYFFDRAGHCEDEGCSWEHSRGESTRCQDQAATTTVSTPPHR RDPPPSPTEYPGPSPPHPRPLCQVCLPLLAQDPGGRGYPLLWPAPCCSCHSELVPSP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes. May play a role in autophagy.; May activate Wnt/beta-catenin signaling to modulate epithelial cell function.
  • 基因功能參考文獻(xiàn):
    1. High GRP137 expression is associated with metastasis in ovarian cancer. PMID: 29739299
    2. findings imply that GPR137 plays an important role in the occurrence and progression of PCa and may prove to be a potential therapeutic target for the treatment of advanced PCa PMID: 26669804
    3. GPR137 as an essential player in urinary bladder cancer cell growth PMID: 25496438
    4. GPR137 knockdown inhibited growth of Daoy medulloblastoma cells via disturbing cell cycle progression and inducing apoptosis PMID: 25524330
    5. GPR137 as a potential oncogene in pancreatic cancer cells PMID: 25471990
    6. Knockdown of GPR137 in HepG2 cells led to cell cycle arrest at G0/G1 phase and G2/M phase, and induced cell apoptosis, as determined by flow cytometry analysis, which contributed to cell growth inhibition. PMID: 25490967
    7. Our results indicated that GPR137 is involved in the progression of human glioma PMID: 24870220
    8. Expression levels of GRP137 were analyzed in different colon cancer cell lines. Silencing of GPR137 reduced the proliferation rate and colony numbers. PMID: 25301753

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Lysosome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    GPR137 family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24300

    KEGG: hsa:56834

    STRING: 9606.ENSP00000411827

    UniGene: Hs.523763



主站蜘蛛池模板: 久久成人a毛片免费观看网站| 久久久久人妻精品一区三寸蜜桃| 亚洲熟女乱色综合亚洲小说| 欧美亚洲色综久久精品国产| 婷婷开心激情综合五月天| 欧美色欧美亚洲高清在线观看| 动漫精品专区一区二区三区不卡| 国产美女裸体丝袜喷水视频 | 色翁荡息又大又硬又粗又爽电影 | 国产成a人亚洲精品无码久久网| 插插无码视频大全不卡网站| 老司机无码精品a| 亚洲日韩在线中文字幕综合 | 亚洲国产成人久久综合一区77| 青青草原精品资源站久久| 在线观看老湿视频福利| 欧美老人巨大xxxx做受视频| 女人被做到高潮免费视频| 凸偷窥中国女人洗澡| 中日产幕无线码一区| 国产国语亲子伦亲子| 亚洲国产aⅴ成人精品无吗| 国产成人综合久久三区| 色情无码www视频无码区澳门| 男女性高爱潮免费观看| 久久精品中文字幕一区| 亚洲最大无码中文字幕| 韩国精品无码少妇在线观看| 欧美精品中文字幕在线视| 把插八插露脸对白内射| 亚洲一卡二卡三卡四卡| 国产极品美女高潮抽搐免费网站 | 无码人妻一区二区三区免费| 欧美品无码一区二区三区在线蜜桃 | 欧洲精品99毛片免费高清观看| 少妇人妻综合久久中文字幕| 欧美肥老太牲交| 国产又色又刺激高潮视频| 99精品欧美一区二区三区| 亚洲综合色丁香婷婷六月图片 | 欧美黑人性暴力猛交喷水|