在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Enteropeptidase (TMPRSS15)

  • 中文名稱:
    人TMPRSS15重組蛋白
  • 貨號:
    CSB-CF018824HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    TMPRSS15
  • Uniprot No.:
  • 別名:
    TMPRSS15; ENTK; PRSS7; Enteropeptidase; Enterokinase; Serine protease 7; Transmembrane protease serine 15
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-784
  • 氨基酸序列
    GSKRGISSRHHSLSSYEIMFAALFAILVVLCAGLIAVSCLTIKESQRGAALGQSHEARATFKITSGVTYNPNLQDKLSVDFKVLAFDLQQMIDEIFLSSNLKNEYKNSRVLQFENGSIIVVFDLFFAQWVSDENVKEELIQGLEANKSSQLVTFHIDLNSVDILDKLTTTSHLATPGNVSIECLPGSSPCTDALTCIKADLFCDGEVNCPDGSDEDNKMCATVCDGRFLLTGSSGSFQATHYPKPSETSVVCQWIIRVNQGLSIKLSFDDFNTYYTDILDIYEGVGSSKILRASIWETNPGTIRIFSNQVTATFLIESDESDYVGFNATYTAFNSSELNNYEKINCNFEDGFCFWVQDLNDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLNETVKFKVAFNAFKNKILSDIALDDISLTYGICNGSLYPEPTLVPTPPPELPTDCGGPFELWEPNTTFSSTNFPNSYPNLAFCVWILNAQKGKNIQLHFQEFDLENINDVVEIRDGEEADSLLLAVYTGPGPVKDVFSTTNRMTVLLITNDVLARGGFKANFTTGYHLGIPEPCKADHFQCKNGECVPLVNLCDGHLHCEDGSDEADCVRFFNGTTNNNGLVRFRIQSIWHTACAENWTTQISNDVCQLLGLGSGNSSKPIFPTDGGPFVKLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDITPKI
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
  • 基因功能參考文獻:
    1. The Y174R variant showed improved specificities for substrates containing the sequences DDDDK (kcat/KM = 6.83 x 106 M-1 sec-1) and DDDDR (kcat/KM = 1.89 x 107 M-1 sec-1) relative to all other enteropeptidase variants reported to date. PMID: 23436726
    2. Enteropeptidase is a gene associated with a starvation human phenotype and a novel target for obesity treatment PMID: 23185382
    3. Human enteropeptidase shows 10x faster kinetics compared to other animal sources but low solubility under low salt conditions. A supercharged variant of enteropeptidase light chain with increased solubility was used for crystallization. PMID: 22488687
    4. Characterization of the different catalytic activity of human and bovine enteropeptidase light chains toward hydrolysis of peptides and proteins lacking tetraaspartate sequence. PMID: 22571433
    5. Engineered recombinant enteropeptidase catalytic subunit: effect of N-terminal modification PMID: 11913964
    6. Produced in enterocytes and goblet cells. Localization on brush border of cells for physiological activation of digestive enzymes. In duodenal polyps and adenocarcinoma at duodenum but not in Brunner's gland adenoma. PMID: 12907431
    7. Enterokinase directly cleaved proMMP-9 at the Lys65-Ser66 site. PMID: 18062964

    顯示更多

    收起更多

  • 相關疾病:
    Enterokinase deficiency (ENTKD)
  • 亞細胞定位:
    Membrane; Single-pass type II membrane protein.
  • 蛋白家族:
    Peptidase S1 family
  • 組織特異性:
    Intestinal brush border.
  • 數據庫鏈接:

    HGNC: 9490

    OMIM: 226200

    KEGG: hsa:5651

    STRING: 9606.ENSP00000284885

    UniGene: Hs.149473



主站蜘蛛池模板: 无码人妻丰满熟妇精品区| 亚洲欧美在线观看| 国产成人无码av在线播放dvd| 一本久道久久综合狠狠爱| 亚洲高清专区日韩精品| 日本又黄又潮娇喘视频| 未满十八勿入午夜免费网站| 色综合天天综合网国产成人网| www国产亚洲精品| 亚洲综合一区无码精品| 日本中文一二区有码在线| 最新 国产 精品 精品 视频| 丰满肥臀大屁股熟妇激情视频| 日本熟妇人妻中出| 亚洲黑人巨大videos| 国产女人高潮抽搐叫床视频| 久久综合久中文字幕青草| 精品久久久久中文字幕一区| 精品国产乱码久久久久软件| 狠狠色噜噜狠狠狠888777米奇| 蜜臀avwww国产天堂| 鲁丝一区二区三区免费| 国产精品无码a∨精品影院app| 亚洲开心婷婷中文字幕 | 无码人妻h动漫中文字幕| 免费大黄网站在线观| 国产情侣大量精品视频| 337p日本欧洲亚洲大胆人人| 日韩精品一区二区三区在线观看| 人妻被按摩师玩弄到潮喷| 免费国产成人午夜福利电影| 麻豆国产av超爽剧情系列| 久久精品黄aa片一区二区三区 | 精品一区二区三区在线观看| 亚洲欧美一区二区三区日产| 久久精品无码一区二区app | 亚洲日韩亚洲另类| 美女视频黄a视频全免费| 又粗又猛又黄又爽无遮挡| 国产精品禁18久久久夂久| 国产精品亚韩精品无码a在线|