在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Bombesin receptor-activated protein C6orf89 (C6orf89)

  • 中文名稱:
    Recombinant Human Bombesin receptor-activated protein C6orf89(C6orf89)
  • 貨號:
    CSB-CF764939HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    C6orf89
  • Uniprot No.:
  • 別名:
    C6orf89; BRAP; UNQ177/PRO203; Bombesin receptor-activated protein C6orf89; Amfion
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-347
  • 氨基酸序列
    MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRPPPQYPLLIV VYKVLATLGLILLTAYFVIQPFSPLAPEPVLSGAHTWRSLIHHIRLMSLPIAKKYMSENK GVPLHGGDEDRPFPDFDPWWTNDCEQNESEPIPANCTGCAQKHLKVMLLEDAPRKFERLH PLVIKTGKPLLEEEIQHFLCQYPEATEGFSEGFFAKWWRCFPERWFPFPYPWRRPLNRSQ MLRELFPVFTHLPFPKDASLNKCSFLHPEPVVGSKMHKMPDLFIIGSGEAMLQLIPPFQC RRHCQSVAMPIEPGDIGYVDTTHWKVYVIARGVQPLVICDGTAFSEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Exhibits histone deacetylase (HDAC) enhancer properties. May play a role in cell cycle progression and wound repair of bronchial epithelial cells.
  • 基因功能參考文獻:
    1. results suggest BRAP plays an important role in airway inflammation and its overexpression may regulate NE-induced MUC5AC hypersecretion in HBE16 cells via the EGFR/ERK/NF-kappaB signaling pathway PMID: 28476309
    2. Data show that BRAP locates in the membrane and cytoplasm, suggesting that this protein is a cytoplasm protein, which promotes cell cycle and wound repair of HBECs. PMID: 21857995
    3. Data indicate that bombesin receptor-activated protein (BRAP) might increase histone deacetylases 1/2 (HDAC) activity that leads to NF-kappa B (NF-kappaB) activation via its putative C-terminal domain. PMID: 26460487
    4. C60rf89 is a gene that encodes three distinct proteins with the capacity to enhance the activity of histone deacetylases (HDACs) in the nucleolus, the Golgi and the midbody PMID: 23460338
    5. C6orf89 encodes one soluble and two type II membrane proteins that function as histone deacetylase enhancers. The 34sp is selectively targeted to the nucleolus and is retained in nucleolar organizer regions in mitotic cells. The 34sp is integrated into the ribosomal gene transcription machinery and is relocalized to the nucleolus upon the arrest of rDNA transcription, protein synthesis, and PI3K/mTORC signalling. PMID: 23460338
    6. Overexpression of BRAP may play a role during the antigen presenting process of bronchial epithelium by inhibiting the antigen uptake ability of bronchial epithelial cells. PMID: 22930588

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein. Midbody.; [Isoform 2]: Golgi apparatus membrane; Single-pass type II membrane protein. Midbody.; [Isoform 3]: Cytoplasm. Nucleus, nucleolus.
  • 數據庫鏈接:

    HGNC: 21114

    OMIM: 616642

    KEGG: hsa:221477

    STRING: 9606.ENSP00000347322

    UniGene: Hs.433381



主站蜘蛛池模板: 日本久久高清一区二区三区毛片| 在线天堂中文在线资源网| 精品国产精品久久一区免费式| 亚洲亚洲熟妇色l图片20p| 天堂网www最新版官网| 麻豆人妻无码性色av专区| 午夜dj在线观看高清在线视频完整版| 免费无码又爽又高潮视频| 人妻无码一区二区三区免费| 十八禁啪啪无遮挡网站| 国产精品久久自在自线不| 四虎国产精品免费久久久| 色综合久久久久无码专区| 国产精品青青青在线观看| 久久99精品久久久久久不卡| 亚洲国产成人乱码| 亚洲欧美国产成人综合欲网| 亚洲图片校园另激情类小说| 99精品人妻少妇一区二区| 午夜福利理论片在线观看| 成人综合婷婷国产精品久久| 亚洲中文字幕av每天更新| 粉嫩极品国产在线观看| 久久精品国产色蜜蜜麻豆| 成人亚洲a片v一区二区三区蜜臀| 九九99久久精品在免费线18| 亚洲蜜桃v妇女| 狠狠色噜噜狠狠狠888米奇视频| 亚洲综合熟女久久久40p| 香蕉久久人人97超碰caoproen| 无码国内精品人妻少妇蜜桃视频| 国产乱子伦农村叉叉叉| 国产内射xxxxx在线| 国产精品福利一区二区| 毛片免费全部无码播放| 色v99在线影院| 亚洲成av人片在线观看高清| 可以直接免费观看的av网站| 女同性av片在线观看免费网站| 在线精品亚洲一区二区小说| 国产午夜手机精彩视频|