在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Bombesin receptor-activated protein C6orf89 (C6orf89)

  • 中文名稱:
    Recombinant Human Bombesin receptor-activated protein C6orf89(C6orf89)
  • 貨號:
    CSB-CF764939HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    C6orf89
  • Uniprot No.:
  • 別名:
    C6orf89; BRAP; UNQ177/PRO203; Bombesin receptor-activated protein C6orf89; Amfion
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-347
  • 氨基酸序列
    MDLAANEISIYDKLSETVDLVRQTGHQCGMSEKAIEKFIRQLLEKNEPQRPPPQYPLLIV VYKVLATLGLILLTAYFVIQPFSPLAPEPVLSGAHTWRSLIHHIRLMSLPIAKKYMSENK GVPLHGGDEDRPFPDFDPWWTNDCEQNESEPIPANCTGCAQKHLKVMLLEDAPRKFERLH PLVIKTGKPLLEEEIQHFLCQYPEATEGFSEGFFAKWWRCFPERWFPFPYPWRRPLNRSQ MLRELFPVFTHLPFPKDASLNKCSFLHPEPVVGSKMHKMPDLFIIGSGEAMLQLIPPFQC RRHCQSVAMPIEPGDIGYVDTTHWKVYVIARGVQPLVICDGTAFSEL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Exhibits histone deacetylase (HDAC) enhancer properties. May play a role in cell cycle progression and wound repair of bronchial epithelial cells.
  • 基因功能參考文獻:
    1. results suggest BRAP plays an important role in airway inflammation and its overexpression may regulate NE-induced MUC5AC hypersecretion in HBE16 cells via the EGFR/ERK/NF-kappaB signaling pathway PMID: 28476309
    2. Data show that BRAP locates in the membrane and cytoplasm, suggesting that this protein is a cytoplasm protein, which promotes cell cycle and wound repair of HBECs. PMID: 21857995
    3. Data indicate that bombesin receptor-activated protein (BRAP) might increase histone deacetylases 1/2 (HDAC) activity that leads to NF-kappa B (NF-kappaB) activation via its putative C-terminal domain. PMID: 26460487
    4. C60rf89 is a gene that encodes three distinct proteins with the capacity to enhance the activity of histone deacetylases (HDACs) in the nucleolus, the Golgi and the midbody PMID: 23460338
    5. C6orf89 encodes one soluble and two type II membrane proteins that function as histone deacetylase enhancers. The 34sp is selectively targeted to the nucleolus and is retained in nucleolar organizer regions in mitotic cells. The 34sp is integrated into the ribosomal gene transcription machinery and is relocalized to the nucleolus upon the arrest of rDNA transcription, protein synthesis, and PI3K/mTORC signalling. PMID: 23460338
    6. Overexpression of BRAP may play a role during the antigen presenting process of bronchial epithelium by inhibiting the antigen uptake ability of bronchial epithelial cells. PMID: 22930588

    顯示更多

    收起更多

  • 亞細胞定位:
    [Isoform 1]: Golgi apparatus membrane; Single-pass type II membrane protein. Midbody.; [Isoform 2]: Golgi apparatus membrane; Single-pass type II membrane protein. Midbody.; [Isoform 3]: Cytoplasm. Nucleus, nucleolus.
  • 數據庫鏈接:

    HGNC: 21114

    OMIM: 616642

    KEGG: hsa:221477

    STRING: 9606.ENSP00000347322

    UniGene: Hs.433381



主站蜘蛛池模板: √天堂中文官网8在线| 狠狠色噜噜狠狠狠狠米奇777| 熟妇人妻不卡中文字幕| 成人丝袜激情一区二区| 俺也来俺也去俺也射| 国产成人综合95精品视频| 午夜国产成人片在线播放| 精品无码av无码免费专区| 日韩成人无码中文字幕| 亚洲精品人成网线在线播放va| 国产裸体xxxx视频在线播放| 日韩一区二区三区高清电影| 亚洲人成在线观看| 亚洲国产午夜精华无码福利| 草草网站影院白丝内射| 色偷偷色噜噜狠狠网站久久 | 加勒比一本heyzo高清视频| 成人爽a毛片免费网站| 亚洲国产品综合人成综合网站| 久久久国产精品无码免费专区| 人妻人人澡人人添人人爽| 亚洲人成人无码www| 欧美自拍亚洲综合图区| 成人午夜福利视频镇东影视| 青青草国产午夜精品| 亚洲国产精品久久久久4婷婷| 人人人妻人人人妻人人人| 精品久久久久久成人av| 日本xxxx色视频在线观看| 亚洲成年看片在线观看| 性欧美熟妇videofreesex| 强插女教师av在线| 少妇大叫太大太爽受不了在线观看| 爆乳2把你榨干哦ova在线观看| 成年女人色毛片| 亚在线第一国产州精品99| 国产成人青青久久大片| 欧美浓毛大泬视频| 美女张开腿让人桶| 久久精品国产亚洲欧美成人| 国产午夜福利伦理300|