在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Human Alkaline ceramidase 1 (ACER1)

  • 中文名稱:
    Recombinant Human Alkaline ceramidase 1(ACER1)
  • 貨號:
    CSB-CF001151HU
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    ACER1; ASAH3; Alkaline ceramidase 1; AlkCDase 1; Alkaline CDase 1; Acylsphingosine deacylase 3; N-acylsphingosine amidohydrolase 3
  • 種屬:
    Homo sapiens (Human)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-264
  • 氨基酸序列
    MPSIFAYQSSEVDWCESNFQYSELVAEFYNTFSNIPFFIFGPLMMLLMHPYAQKRSRYIY VVWVLFMIIGLFSMYFHMTLSFLGQLLDEIAILWLLGSGYSIWMPRCYFPSFLGGNRSQF IRLVFITTVVSTLLSFLRPTVNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLW AVALTSWISDRLLCSFWQRIHFFYLHSIWHVLISITFPYGMVTMALVDANYEMPGETLKV RYWPRDSWPVGLPYVEIRGDDKDC
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Endoplasmic reticulum ceramidase that catalyzes the hydrolysis of ceramides into sphingosine and free fatty acids at alkaline pH. Ceramides, sphingosine, and its phosphorylated form sphingosine-1-phosphate are bioactive lipids that mediate cellular signaling pathways regulating several biological processes including cell proliferation, apoptosis and differentiation. Exhibits a strong substrate specificity towards the natural stereoisomer of ceramides with D-erythro-sphingosine as a backbone and has a higher activity towards very long-chain unsaturated fatty acids like the C24:1-ceramide. May also hydrolyze dihydroceramides to produce dihydrosphingosine. ACER1 is a skin-specific ceramidase that regulates the levels of ceramides, sphingosine and sphingosine-1-phosphate in the epidermis, mediates the calcium-induced differentiation of epidermal keratinocytes and more generally plays an important role in skin homeostasis.
  • 基因功能參考文獻:
    1. regulates the signaling system mediated by sphingolipids PMID: 11915342
    2. upregulation of haCER1 and AC mediates the Ca2+(o)-induced growth arrest and differentiation of keratinocytes by generating sphingosine and its phosphate PMID: 17713573
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Alkaline ceramidase family
  • 組織特異性:
    Mainly expressed in epidermis.
  • 數據庫鏈接:

    HGNC: 18356

    OMIM: 613491

    KEGG: hsa:125981

    STRING: 9606.ENSP00000301452

    UniGene: Hs.352609



主站蜘蛛池模板: 日本高清色本在线www| 亚洲女教师丝祙在线播放| av影音先锋最大资源网| 肉体裸交137日本大胆摄影| 日韩精品人成在线播放| 无码人妻一区二区三区免费| 色老99久久九九爱精品| 亚洲国产码专区| 大肉大捧一进一出好爽| 国产熟妇勾子乱视频| 天天狠天天透天干天天| 好爽好硬好深高潮视频456| 大桥久未无码吹潮在线观看| 免费又黄又裸乳的视频| 四库影院永久国产精品地址| 丰满妇女强制高潮18xxxx| 疯狂撞击丝袜人妻| 久久久久77777人人人人人 | 最美女人体内射精一区二区 | 国产高清在线精品一区免费| 夜夜高潮夜夜爽高清完整版1| 亚洲精品国产福利一区二区| 99久e在线精品视频在线| 一本久道中文无码字幕av| 99热久久这里只有精品| 韩国乱码片免费看| 好爽好舒服要高潮了视频| 成人性能视频在线| 国产av高清无亚洲| 亚洲日本乱码中文在线电影| 黄桃av无码免费一区二区三区| 后入内射欧美99二区视频| 日本熟妇色一本在线视频| 日本中文字幕亚洲乱码| 老熟女 露脸 嗷嗷叫| 热久久99这里有精品综合久久| 欧美日韩国产综合新一区| 国产麻豆精品一区二区三区v视界| 国产成人亚洲精品另类动态| 国产交换配偶在线视频| 少妇内射高潮福利炮|