在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Chicken Gap junction alpha-8 protein (GJA8)

  • 中文名稱:
    雞GJA8重組蛋白
  • 貨號:
    CSB-CF009449CH
  • 規格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產品詳情

  • 基因名:
    GJA8
  • Uniprot No.:
  • 別名:
    GJA8; Gap junction alpha-8 protein; Connexin-45.6; Cx45.6
  • 種屬:
    Gallus gallus (Chicken)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-400
  • 氨基酸序列
    GDWSFLGNILEQVNEQSTVIGRVWLTVLFIFRILILGTAAELVWGDEQSDFVCNTQQPGCENVCYDEAFPISHIRLWVLQIIFVSTPSLVYFGHAVHHVRMEEKRKEREEAERRQQAEVDEEKLPLAPNQNKGNNPDGTKKFRLEGTLLRTYILHIIFKTLFEVGFIVGQYFLYGFRILPLYRCGRWPCPNLVDCFVSRPTEKTIFIMFMLVVAAVSLFLNLVEISHLILKRIRRALRRPAEEQMGEVPEKPLHAIAVSSIPKAKGYKLLEEEKPVSHYFPLTEVGVEPSPLPSAFNEFEEKIGMGPLEDLSRAFDERLPSYAQAKEPEEEKVKAEEEEEQEEEQQAPQEEPGVKKAEEEVVSDEVEGPSAPAELATDVRSLSRLSKASSRARSDDLTV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Structural component of eye lens gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore.
  • 基因功能參考文獻:
    1. the role of the charged residues at the end of TM-1 in voltage sensing in Cx26, Cx46, and Cx50. PMID: 27143357
    2. Cx50 is phosphorylated in vivo by PKA at Ser-395, which promotes increased dye permeability of Cx50 channels and plays an important role in metabolic coupling and transport in lens fibers PMID: 21454606
    3. Val(362) is important for maintaining the helical structure and is crucial for the role of Cx50 in promoting lens epithelial-fiber differentiation PMID: 20395299
    4. These data suggest that the N-terminus plays a critical role in determining many of biophysical properties of Cx45.6 gap junctional channels, including molecular permeability and voltage gating. PMID: 16931554
    5. study concludes that the expression of Cx45.6, but not Cx45.6-dependent gap junction channels, is involved in lens epithelial-fiber cell differentiation, and the C-terminal domain of Cx45.6 plays a predominant role in mediating this process PMID: 17895360
    6. Phosphorylation at Ser(364) appears to stimulate turnover primarily through proteasome pathway; this phosphorylation inhibits cleavage by caspase-3. PMID: 18649174
    7. Human Cx50 is functionally involved in cell differentiation and lens development, and the E48K mutant promotes primary lens cell differentiation indistinguishable from wild-type chicken Cx50, despite its lack of junctional channel function PMID: 19126675

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
  • 蛋白家族:
    Connexin family, Alpha-type (group II) subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 少妇大胆瓣开下部自慰| 日韩精品无码专区免费视频| 麻豆av一区二区三区久久| 香蕉欧美成人精品a∨在线观看| 97无码精品综合| 无码丰满熟妇bbbbxxx| 欧美亚洲精品一区二区| 久久久久久综合网天天| 国产猛男猛女超爽免费视频| 人人狠狠综合久久88成人| 亚洲 欧美 影音先锋| 99精品国产一区二区三区不卡| 国产真实的和子乱拍在线观看| 未满小14洗澡无码视频网站| 好吊妞无缓冲视频观看| 色猫咪免费人成网站在线观看 | 亚洲区激情区无码区日韩区| 色婷婷欧美在线播放内射| 亚洲一区av在线观看| 国产一区二区怡红院| 熟妇激情内射com| 久久久久成人精品| 亚洲男同志网站| 成年日韩片av在线网站| 亚洲中字幕日产av片在线| 草草浮力地址线路①屁屁影院| 国产不卡视频一区二区三区| 久久久久国产精品人妻aⅴ天堂| 99爱在线精品视频免费观看| 亚洲色一区二区三区四区| 老湿机69福利区无码| 亚洲va天堂va欧美ⅴa在线| 久久久久国产精品人妻电影| 国产精品v欧美精品v日韩精品| 日韩精品中文字幕无码一区| 亚洲顶级裸体av片| 亚洲第一福利网站在线观看| 人妻夜夜爽天天爽三区丁香花| 欧洲美熟女乱又伦免费视频| 成人亚洲精品777777| 免费看成人aa片无码视频羞羞网|