在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Bovine Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)

  • 中文名稱:
    Recombinant Bovine Cytochrome c oxidase subunit 4 isoform 1, mitochondrial(COX4I1)
  • 貨號:
    CSB-CF005832BO
  • 規(guī)格:
  • 來源:
    in vitro E.coli expression system
  • 其他:

產(chǎn)品詳情

  • 基因名:
  • Uniprot No.:
  • 別名:
    COX4I1; COX4; Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1
  • 種屬:
    Bos taurus (Bovine)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達(dá)區(qū)域:
    23-169
  • 氨基酸序列
    AHGSVVKSEDYALPSYVDRRDYPLPDVAHVKNLSASQKALKEKEKASWSSLSIDEKVELY RLKFKESFAEMNRSTNEWKTVVGAAMFFIGFTALLLIWEKHYVYGPIPHTFEEEWVAKQT KRMLDMKVAPIQGFSAKWDYDKNEWKK
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunbit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
  • 基因功能參考文獻(xiàn):
    1. Structure of bovine cytochrome c oxidase crystallized at a neutral pH has been reported. PMID: 28695851
    2. Studies indicate that the patterns of charge translocation of cytochrome c oxidase coupled to transfer of the 3rd and 4th electrons are very similar. PMID: 21889506
    3. Studies indicate that time-resolved resonance Raman (RR) spectroscopy of whole mitochondria identified a band at 571cm(-1) arising from the oxygenated intermediate at Deltat=0.4, 0.6 and 1.4ms. PMID: 22172733
    4. Studies indicate that mutational amino acid replacement in proton channels, at the negative (N) side of membrane-inserted prokaryotic aa(3) oxidases, as well as Zn(2+) binding at this site in the bovine oxidase, uncouples proton pumping. PMID: 22100820
    5. Studies indicate that nitric oxide (NO) binding to reduced ba(3) and bovine cytochrome aa3. PMID: 22201543
    6. Studies indicate that X-ray structure of heart cytochrome c oxidase (CcO) suggest that O(2) molecules are transiently trapped at the Cu(B) site before binding to Fe(a3)(2+) to provide O(2)(-). PMID: 22236806
    7. Studies indicate that photoexcitation of Ru (II) to Ru(II*) leads to rapid electron transfer to the ferric heme group in cytochrome c (Cc), followed by electron transfer to Cu(A) in cytochrome c oxidase (CcO) with a rate constant of 60,000s(-1). PMID: 21939635
    8. Studies suggest that the master-equation models address the question of how pumping can be achieved in a system in which all reaction steps are reversible. PMID: 21946020
    9. Studies suggest for the His291 model of proton pumping in cytochrome c oxidase (CcO). PMID: 22086149

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 蛋白家族:
    Cytochrome c oxidase IV family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 成人亚洲a片v一区二区三区动漫 | 韩日综合成人中文字幕| 99精品国产综合久久久久五月天 | 成人永久免费网站在线观看 | 久久人妻av无码中文专区| 中文字幕人成乱码熟女免费 | 亚洲精品久久久无码av片软件| 国产精品青青在线麻豆| 中文字幕日韩人妻不卡一区| 日韩99在线 | 中文| 中文字幕精品亚洲无线码一区| 久久99精品国产麻豆| 日韩av无码成人无码免费| 国产精品国产三级国产an| 好爽...又高潮了毛片| 国产一区二区三区无码免费| 国产男女爽爽爽免费视频| 国产尤物av尤物在线看| 岛国4k人妻一区二区三区| 日本真人边吃奶边做爽电影| 国产欧美亚洲精品a| 男女猛烈无遮挡免费视频| 九九精品成人免费国产片| 亚洲精品宾馆在线精品酒店| 午夜高清国产拍精品| 国产网红无码精品视频| 人妻 丝袜美腿 中文字幕| 综合久久国产九一剧情麻豆| 亚洲h成年动漫在线观看网站 | 美女裸体跪姿扒开屁股无内裤 | 99国内精品久久久久久久| 精品无人区卡一卡二卡三乱码| 成人无码免费视频在线播| 丰满熟女高潮毛茸茸欧洲视频| 国产精品久久久久9999爆乳| 成年免费视频黄网站在线观看| 国产日产欧产精品精品app| 欧美性猛交内射兽交老熟妇| 97精品人妻一区二区三区香蕉| 欧美专区日韩视频人妻| 欧洲精品卡一卡二卡三|