在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Zaire ebolavirus RNA-directed RNA polymerase L (L), partial

  • 中文名稱:
    Recombinant Zaire ebolavirus RNA-directed RNA polymerase L(L) ,partial
  • 貨號:
    CSB-YP313164ZAB
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Zaire ebolavirus RNA-directed RNA polymerase L(L) ,partial
  • 貨號:
    CSB-EP313164ZAB-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Zaire ebolavirus RNA-directed RNA polymerase L(L) ,partial
  • 貨號:
    CSB-BP313164ZAB
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Zaire ebolavirus RNA-directed RNA polymerase L(L) ,partial
  • 貨號:
    CSB-MP313164ZAB
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    L
  • Uniprot No.:
  • 別名:
    LRNA-directed RNA polymerase L; Protein L; Large structural protein; Replicase; Transcriptase) [Includes: RNA-directed RNA polymerase; EC 2.7.7.48); mRNA; guanine-N(7)-)-methyltransferase; EC 2.1.1.56); GDP polyribonucleotidyltransferase; EC 2.7.7.88); Cap-specific mRNA; nucleoside-2'-O-)-methyltransferase 2; EC 2.1.1.296)]
  • 種屬:
    Zaire ebolavirus (strain Mayinga-76) (ZEBOV) (Zaire Ebola virus)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    RNA-directed RNA polymerase that catalyzes the transcription of viral mRNAs, their capping and polyadenylation. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The viral polymerase binds to the genomic RNA at the 3' leader promoter, and transcribes subsequently all viral mRNAs with a decreasing efficiency. The first gene is the most transcribed, and the last the least transcribed. The viral phosphoprotein acts as a processivity factor. Capping is concommitant with initiation of mRNA transcription. Indeed, a GDP polyribonucleotidyl transferase (PRNTase) adds the cap structure when the nascent RNA chain length has reached few nucleotides. Ribose 2'-O methylation of viral mRNA cap precedes and facilitates subsequent guanine-N-7 methylation, both activities being carried by the viral polymerase. Polyadenylation of mRNAs occur by a stuttering mechanism at a slipery stop site present at the end viral genes. After finishing transcription of a mRNA, the polymerase can resume transcription of the downstream gene.; RNA-directed RNA polymerase that catalyzes the replication of viral genomic RNA. The template is composed of the viral RNA tightly encapsidated by the nucleoprotein (N). The replicase mode is dependent on intracellular N protein concentration. In this mode, the polymerase replicates the whole viral genome without recognizing transcriptional signals, and the replicated genome is not caped or polyadenylated.
  • 基因功能參考文獻:
    1. Authors found that the phosphodiester bridge-cleaving and recombination activities of TOP1 are required for the polymerase activity of Ebola virus L protein. PMID: 23658456
    2. A core binding domain spanning amino acids 280-370 of L was sufficient to mediate weak interaction with VP35, while the entire N-terminus up to amino acid 380 was required for strong VP35-L binding. PMID: 23582637
  • 亞細胞定位:
    Virion. Host cytoplasm.
  • 數據庫鏈接:

    KEGG: vg:911824



主站蜘蛛池模板: 乌克兰少妇xxxx做受野外| 国产精品女上位好爽在线| av无码动漫一区二区三区精品| 92国产精品午夜福利无毒不卡| 国产精品亚亚洲欧关中字幕| 亚洲欧美日韩久久精品第一区| 亚洲熟妇无码乱子av电影| 亚洲香蕉网久久综合影视| 18禁无遮挡羞羞污污污污网站| 国内精品久久久久影院日本| 欧美xxxx做受欧美| 亚洲暴爽av天天爽日日碰| 国产精品久久久久电影网| 最爽爱爱高潮免费视频| 2018av天堂在线视频精品观看| 成 人 色综合 综合网站| 女人爽到高潮视频免费直播| 精品无人码麻豆乱码1区2区 | 男人av无码天堂| 国产成人精品日本亚洲 | 国产亚洲综合欧美一区二区| 免费毛片全部不收费的| 一本久道久久综合狠狠躁av| 亚洲乱码卡一卡二卡新区中国| 亚洲卡一卡二新区| 亚洲一区二区三区四区| 中文在线最新版天堂| 久久人妻无码aⅴ毛片a片app| 久久久久久亚洲综合影院| 亚洲日韩精品无码专区| …日韩人妻无码精品一专区| 久久综合给合久久狠狠狠88| 狂野欧美激情性xxxx按摩| 啦啦啦www播放日本观看| 男女野外做爰全过程69影院| 亚洲乱码卡一卡二卡新区仙踪木木 | 亚洲精品国产品国语在线| 人人玩人人添人人澡| 欧美日韩无线码在线观看| 国产av寂寞骚妇| 欧美丰满肥婆videos|