在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Human Charged multivesicular body protein 1b (CHMP1B)

Recombinant Human Charged multivesicular body protein 1b (CHMP1B)

  • 中文名稱：
    Recombinant Human Charged multivesicular body protein 1b(CHMP1B)
  • 貨號：
    CSB-YP748726HU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Human Charged multivesicular body protein 1b(CHMP1B)
  • 貨號：
    CSB-EP748726HU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Human Charged multivesicular body protein 1b(CHMP1B)
  • 貨號：
    CSB-BP748726HU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Human Charged multivesicular body protein 1b(CHMP1B)
  • 貨號：
    CSB-MP748726HU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    CHMP1B; C18orf2Charged multivesicular body protein 1b; CHMP1.5; Chromatin-modifying protein 1b; CHMP1b; Vacuolar protein sorting-associated protein 46-2; Vps46-2; hVps46-2
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-199
  • 氨基酸序列
    MSNMEKHLFN LKFAAKELSR SAKKCDKEEK AEKAKIKKAI QKGNMEVARI HAENAIRQKN QAVNFLRMSA RVDAVAARVQ TAVTMGKVTK SMAGVVKSMD ATLKTMNLEK ISALMDKFEH QFETLDVQTQ QMEDTMSSTT TLTTPQNQVD MLLQEMADEA GLDLNMELPQ GQTGSVGTSV ASAEQDELSQ RLARLRDQV
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.
  • 基因功能參考文獻(xiàn)：
    1. The interaction between CL7MIT and CHMP1B and between CL7MIT and IST1 became stronger when IST1 or CHMP1B was additionally coexpressed, suggesting formation of ternary complex of calpain-7, IST1 and CHMP1B. PMID: 21616915
    2. CHMP1B is bound by the VPS4A microtubule interacting and transport (MIT) domain. PMID: 16174732
    3. UBPY MIT domain and another ubiquitin isopeptidase, AMSH, reveals common interactions with CHMP1A and CHMP1B but a distinct selectivity of AMSH for CHMP3/VPS24, a core subunit of the ESCRT-III complex, and UBPY for CHMP7. PMID: 17711858
    4. The 2.5-A structure of the C-terminal tail of CHMP1B with the MIT domain of spastin reveals a specific, high-affinity complex involving a noncanonical binding site between the first and third helices of the MIT domain. PMID: 18997780
  • 亞細(xì)胞定位：
    Cytoplasm, cytosol. Endosome. Late endosome membrane; Peripheral membrane protein. Note=Localizes to the midbody of dividing cells, colocalizing with CEP55 and CHMP5. Localized at the periphery of the Fleming body.
  • 蛋白家族：
    SNF7 family
  • 組織特異性：
    Widely expressed. Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta and brain.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 24287

    OMIM: 606486

    KEGG: hsa:57132

    STRING: 9606.ENSP00000432279

    UniGene: Hs.656244



主站蜘蛛池模板： 国产成人精品aa毛片| 四虎国产精品永久地址入口| 国产区在线观看成人精品| 性xxxx欧美老妇506070| 浴室人妻的情欲hd三级国产 | 亚洲国产成人久久综合下载| 四房播色综合久久婷婷| 人人澡人人妻人人爽人人蜜桃麻豆 | 欧洲多毛裸体xxxxx| 交换交换乱杂烩系列yy| 无码国模大尺度视频在线观看| 男女啪啪高清无遮挡免费| 中文字幕亚洲无线码在线一区| 香蕉久久一区二区三区啪啪| 精品乱码无人区一区二区| 天堂av无码av在线a√| 无码乱人伦一区二区亚洲| 日产电影一区二区三区| 99国产精品久久久蜜芽| 日韩免费无码人妻波多野| 精品无码久久久久国产| 国产极品美女高潮无套在线观看| 欧美人与禽猛交狂配| 国产欧洲精品自在自线官方| 欧美性猛交内射兽交老熟妇| 国产999精品久久久久久| 无码中文人妻在线三区| 好爽好湿好硬好大免费视频| 欧美日韩亚洲国内综合网| 怡红院免费的全部视频| 制服视频在线一区二区| 性色av一区二区三区人妻| 色综亚洲国产vv在线观看| 无尺码精品产品视频| 亚洲中文字幕不卡无码| 伊人av超碰伊人久久久| 巨胸不知火舞露双奶头无遮挡| 成人无遮羞视频在线观看| 韩国三级l中文字幕无码| 久久偷看各类wc女厕嘘嘘偷窃| 高潮毛片无遮挡高清视频播放|