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  4. Recombinant Xenopus tropicalis Transcription factor Sox-3 (sox3)

Recombinant Xenopus tropicalis Transcription factor Sox-3 (sox3)

  • 中文名稱：
    熱帶爪蟾sox3重組蛋白
  • 貨號：
    CSB-YP737884XBF
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    熱帶爪蟾sox3重組蛋白
  • 貨號：
    CSB-EP737884XBF
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    熱帶爪蟾sox3重組蛋白
  • 貨號：
    CSB-EP737884XBF-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    熱帶爪蟾sox3重組蛋白
  • 貨號：
    CSB-BP737884XBF
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    熱帶爪蟾sox3重組蛋白
  • 貨號：
    CSB-MP737884XBF
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    sox3
  • Uniprot No.：
  • 別名：
    sox3; Transcription factor Sox-3
  • 種屬：
    Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-307
  • 氨基酸序列
    MYSMLDTDLK SPVQQSNAPN GGPGTPGGKG NASIPDQERV KRPMNAFMVW SRGQRRKMAQ ENPKMHNSEI SKRLGADWKL LSDSEKRPFI DEAKRLRAVH MKEYPDYKYR PRRKTKTLLK KDKYSLPGNL LAPGVSPVAS SVGVGQRIDT YAHMNGWTNG AYSLMQDQLG YSQHPGMNSP QMQQIQHRYD MGGLQYSPMM SSAQTYMNAA ASTYSMSPAY NQQSSTVMSL GSMGSVVKSE PSSPPPAITS HTQRACLGDL RDMISMYLPP GGDASDPSSL QSSRLHSVHQ HYQSAAGPNG TVPLTHI
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcription factor with sequence-specific DNA binding activity. Binds to the consensus sequence 5'-[AT][AT]CAA[AT]G-3', showing a preference for 5'-AACAAT-3' and 5'-AACAAAG-3'. Inhibits beta-catenin-mediated dorsal axis specification by binding to sites within the promoter of the beta-catenin-regulated gene nodal5. Maternally derived sox3 acts as a transcriptional repressor of nodal5 and nodal6 to restrict their expression to the vegetal hemisphere of early embryos and thus establish germ layer formation. Acts at multiple points to inhibit nodal signaling, repressing the expression of the other mesoderm-inducing nodal genes nodal, nodal2 and nodal4, and also acting downstream to induce expression of genes including trim33/ectodermin, ema and coco, whose products repress nodal signaling.
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 數據庫鏈接：


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