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Recombinant Xenopus laevis Vitamin D3 receptor (vdr)

  • 中文名稱:
    有爪蟾蜍vdr重組蛋白
  • 貨號:
    CSB-YP025832XBE
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    有爪蟾蜍vdr重組蛋白
  • 貨號:
    CSB-EP025832XBE
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    有爪蟾蜍vdr重組蛋白
  • 貨號:
    CSB-EP025832XBE-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    有爪蟾蜍vdr重組蛋白
  • 貨號:
    CSB-BP025832XBE
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    有爪蟾蜍vdr重組蛋白
  • 貨號:
    CSB-MP025832XBE
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    vdr; nr1i1; Vitamin D3 receptor; VDR; 1,25-dihydroxyvitamin D3 receptor; Nuclear receptor subfamily 1 group I member 1
  • 種屬:
    Xenopus laevis (African clawed frog)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-422
  • 氨基酸序列
    MEFMAATTSI ADTDMEFDKN VPRICGVCGD KATGFHFNAM TCEGCKGFFR RSMKRKAMFT CPFNGDCRIT KDNRRHCQSC RLKRCVDIGM MKEFILTDEE VQRKRQMINK RKSEEALKES MRPKISDEQQ KMIDILLEAH RKTFDTTYSD FNKFRPPVRE NVDPFRRITR SSSVHTQGSP SEDSDVFTSS PDSSEHGFFS ASLFGQFEYS SMGGKSGELS MLPHIADLVS YSIQKIIGFA KMIPGFRDLI AEDQIALLKS SVIEVIMLRS NQSFSLDDMS WTCGSEDFKY KVDDVTQAGH NMELLEPLVK FQVGLKKLDL HEEEHVLLMA ICILSPDRPG LQDKALVESI QDRLSSTLQT YILCKHPPPG SRLLYAKMIQ KLADLRSLNE EHSKQYRSIS FLPEHSMKLT PLMLEVFSDE IP
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Nuclear hormone receptor family, NR1 subfamily
  • 組織特異性:
    Detected in all tissues examined. Highest level in small intestine and skin.
  • 數據庫鏈接:

    KEGG: xla:378575

    UniGene: Xl.638



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