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  4. Recombinant Xenopus laevis Nucleosome assembly protein 1-like 1-A (nap1l1-a)

Recombinant Xenopus laevis Nucleosome assembly protein 1-like 1-A (nap1l1-a)

  • 中文名稱：
    有爪蟾蜍nap1l1-a重組蛋白
  • 貨號：
    CSB-YP703158XBE
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    有爪蟾蜍nap1l1-a重組蛋白
  • 貨號：
    CSB-EP703158XBE
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    有爪蟾蜍nap1l1-a重組蛋白
  • 貨號：
    CSB-EP703158XBE-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    有爪蟾蜍nap1l1-a重組蛋白
  • 貨號：
    CSB-BP703158XBE
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    有爪蟾蜍nap1l1-a重組蛋白
  • 貨號：
    CSB-MP703158XBE
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    nap1l1-a
  • Uniprot No.：
  • 別名：
    nap1l1-a; nap1-a; Nucleosome assembly protein 1-like 1-A; xNAP1L-A; Nucleosome assembly protein 1; NAP-1; NAP1; xNAP-1; xNAP1
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-392
  • 氨基酸序列
    MANIDNKGQT ELDQQDMEDV EDVEEEETGE DANSKARQLT AQMMQNPQVL AALQERLDDL VGTPTGYIES LPKVVKRRVN ALKNLQVKCA QIEAKFYEEV HELERKYAAL YQPLFDKRSD IINATYEPTE EECEWKVEEE DISGDLKEKA KLEEEKKDEE KEDPKGIPEF WLTVFKNVDL LSDMLQEHDE PILKHLKDIK VKFSDAGQPM SFTLEFYFEP NEFFTNEVLT KTYKMRSEPD ESDPFSFDGP EIMGCTGCLI DWKKGKNVTL KTIKKKQKHK GRGTVRTVTK TVPNDSFFNF FTPPEVPENG ELDDDAEAIL TADFEIGHFL RERIIPRSVL YFTGEAIEDD DDDYDEEGEE ADDEEGEEEA DEDNDPDYEP KKGQNPAECK QQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a chaperone for the linker histone to facilitate deposition of histone B4 onto linker DNA. Required for both remodeling of sperm chromatin into nucleosomes, and linker histone binding to nucleosome core dimers. Plays a role in tissue-specific gene regulation. Required for primitive hemopoiesis, acting upstream of tal1/scl.
  • 基因功能參考文獻：
    1. Data suggest that Nap1 readily dissociates histone 1 (H1) from DNA and stoichiometrically binds H1 from nucleosomes, supporting a hypothesis whereby histone chaperones contribute to regulation of H1 profile in chromatin. PMID: 27010485
    2. role for xNAP1L in tissue-restricted gene regulation PMID: 14550533
    3. results strongly suggest that NAP-1 functions as a chaperone for the linker histone in Xenopus eggs PMID: 15928086
    4. Over-expression of a structural and functional domain in xNAP1 that affects axial patterning in Xenopus. PMID: 16982648
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Nucleosome assembly protein (NAP) family
  • 組織特異性：
    Initially expressed throughout the embryo with expression higher at the animal pole. Becomes localized to presumptive ectoderm by gastrula stages. By stage 18 (neurula), expressed in the neural plate and posterior to the cement gland. In late neurula/earl
  • 數據庫鏈接：

    KEGG: xla:398176

    UniGene: Xl.21960



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