在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Xenopus laevis Neurogenic locus notch protein homolog (notch1), partial

  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-YP322025XBE
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-EP322025XBE
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-EP322025XBE-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-BP322025XBE
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-MP322025XBE
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    notch1; xotch; Neurogenic locus notch homolog protein 1; Notch 1; xOTCH) [Cleaved into: Notch 1 extracellular truncation; NEXT); Notch 1 intracellular domain; NICD)]
  • 種屬:
    Xenopus laevis (African clawed frog)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4(+) and CD8(+) cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).
  • 基因功能參考文獻:
    1. Notch initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 PMID: 21610033
    2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh expression in the midline. PMID: 21276789
    3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 gene or the constitutively active form of Notch (IC). PMID: 21194527
    4. ZFP423 coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression. PMID: 20547764
    5. results suggest that a cell-to-cell interaction via the Notch/Su(H) pathway has a significant role in the PGC migration by regulating cell motility PMID: 20151992
    6. the process of delimiting the three germ layers requires Notch signaling. PMID: 20079726
    7. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis PMID: 15172688
    8. Notch signaling is activated when activin-like signaling induces various tissues from homogenous undifferentiated cells. PMID: 15300513
    9. Notch controls smad2 nuclear localization and the competence of ectodermal cells for activin A in Xenopus embryos PMID: 15817224
    10. Notch signaling has a role during the prepatterning of the cardiac mesoderm PMID: 19580804

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.; [Notch 1 intracellular domain]: Nucleus.
  • 蛋白家族:
    NOTCH family
  • 數據庫鏈接:

    KEGG: xla:394367

    UniGene: Xl.1057



主站蜘蛛池模板: 亚洲一区日韩高清中文字幕亚洲| 熟女体下毛毛黑森林| 狠狠色综合网久久久久久| 日韩精品无码一区二区三区视频| 麻豆国产va免费精品高清在线| 亚洲aⅴ无码专区在线观看| 亚洲kkk4444在线观看| 舌头伸进去搅动好爽视频| 亚洲乱码国产乱码精品精| 大肉大捧一进一出好爽视频动漫| 亚在线第一国产州精品99| 亚洲精品国产高清一线久久| 成人爽a毛片免费| 国产熟妇高潮叫床视频播放| 永久免费看啪啪的网站| 亚洲sm另类一区二区三区| 亚洲精品午夜国产va久久成人| 久久久久无码精品亚洲日韩| 欧美老妇bbbwwbbbww| 亚洲成a人片在线观看天堂无码不卡| 亚洲线精品一区二区三区影音先锋| 熟睡人妻被讨厌的公侵犯| 亚洲337少妇裸体艺术| 亚洲欧美在线制服丝袜国产| 欧美日本免费一区二区三区| 女人高潮流白浆视频| 一二三四视频社区3在线高清| 亚洲自偷自偷偷色无码中文| 在线亚洲人成电影网站色www| 亚洲最大日夜无码中文字幕| 欧美日本亚洲韩国一区| 亚洲精品乱码久久久久久按摩 | 粗大猛烈进出高潮视频| 国产在线精品一区二区三区不卡| 久久www成人_看片免费不卡| 日日摸日日碰夜夜爽亚洲综合 | 大黑人交xxxx18视频| 各处沟厕大尺度偷拍女厕嘘嘘| 国产欧美va天堂在线电影| 极品美女扒开粉嫩小泬图片| 国内露脸中年夫妇交换|