在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Xenopus laevis Neurogenic locus notch protein homolog (notch1), partial

  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-YP322025XBE
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-EP322025XBE
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-EP322025XBE-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-BP322025XBE
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    有爪蟾蜍notch1重組蛋白
  • 貨號:
    CSB-MP322025XBE
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    notch1; xotch; Neurogenic locus notch homolog protein 1; Notch 1; xOTCH) [Cleaved into: Notch 1 extracellular truncation; NEXT); Notch 1 intracellular domain; NICD)]
  • 種屬:
    Xenopus laevis (African clawed frog)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the maturation of both CD4(+) and CD8(+) cells in the thymus. Important for follicular differentiation and possibly cell fate selection within the follicle. During cerebellar development, functions as a receptor for neuronal DNER and is involved in the differentiation of Bergmann glia. Represses neuronal and myogenic differentiation. May play an essential role in postimplantation development, probably in some aspect of cell specification and/or differentiation. May be involved in mesoderm development, somite formation and neurogenesis. Involved in determination of left/right symmetry by modulating the balance between motile and immotile (sensory) cilia at the left-right organiser (LRO).
  • 基因功能參考文獻:
    1. Notch initially destabilises beta-catenin in a process that does not depend on its phosphorylation by GSK3 PMID: 21610033
    2. Notch signaling promotes floor plate and hypochord fates over notochord, but has variable effects on Shh expression in the midline. PMID: 21276789
    3. Transgenic tadpoles were prepared with an elastase promoter driving either the stromelysin-3 gene or the constitutively active form of Notch (IC). PMID: 21194527
    4. ZFP423 coordinates Notch1 and bone morphogenetic protein signaling, selectively up-regulating Hes5 gene expression. PMID: 20547764
    5. results suggest that a cell-to-cell interaction via the Notch/Su(H) pathway has a significant role in the PGC migration by regulating cell motility PMID: 20151992
    6. the process of delimiting the three germ layers requires Notch signaling. PMID: 20079726
    7. the combination of XSICD-mediated intracellular signaling and the extracellular domain of Notch ligands-mediated activation of Notch receptor is involved in the primary neurogenesis PMID: 15172688
    8. Notch signaling is activated when activin-like signaling induces various tissues from homogenous undifferentiated cells. PMID: 15300513
    9. Notch controls smad2 nuclear localization and the competence of ectodermal cells for activin A in Xenopus embryos PMID: 15817224
    10. Notch signaling has a role during the prepatterning of the cardiac mesoderm PMID: 19580804

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.; [Notch 1 intracellular domain]: Nucleus.
  • 蛋白家族:
    NOTCH family
  • 數據庫鏈接:

    KEGG: xla:394367

    UniGene: Xl.1057



主站蜘蛛池模板: 国产亚洲日韩在线a不卡| 欧美人与动交视频在线观看| 极品国产主播粉嫩在线| 无码乱肉视频免费大全合集| 国产精品对白刺激久久久| 国产人澡人澡澡澡人碰视频| 又粗又紧又湿又爽的视频| 香草乱码一二三四区别| 四川丰满少妇被弄到高潮| 欧美性xxxx极品少妇| 亚洲乱码卡一卡二卡新区中国| 午夜成人无码片在线观看影院| 国产欧美另类久久久精品不卡 | 国产又色又爽又黄的视频在线观看 | 深夜福利在线观看视频| 国产精品理论片在线观看| 亚洲va在线va天堂xxxx| 99久久er热在这里只有精品99 | 国产欧美日韩| 男人的天堂av社区在线| 国产人成午夜免电影费观看| 一本大道久久久久精品嫩草| 狠狠色噜噜狠狠色综合久| 免费啪视频在线观看视频日本| 国产av国片精品jk制服丝袜| 国产人妻人伦精品1国产丝袜| 国产精品久人妻精品| 久热爱精品视频线路一 | 波多野结衣在线观看一码| 亚洲中文字幕乱码电影| 国产欧美一区二区精品仙草咪| 老熟女重囗味hdxx70星空| 亚洲欧美中文字幕5发布| 狠狠色噜噜狠狠狠7777米奇| 无码午夜福利免费区久久| 非洲人与性动交ccoo| 国产精品国语对白露脸在线播放| 男人把女人桶到爽免费应用| 久久狠狠高潮亚洲精品| 国产玉足脚交极品在线播放| 国产av无码精品色午夜|