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  4. Recombinant Xenopus laevis Iroquois-class homeodomain protein irx-1-B (irx1-b)

Recombinant Xenopus laevis Iroquois-class homeodomain protein irx-1-B (irx1-b)

  • 中文名稱：
    有爪蟾蜍irx1-b重組蛋白
  • 貨號：
    CSB-YP650344XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    有爪蟾蜍irx1-b重組蛋白
  • 貨號：
    CSB-EP650344XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    有爪蟾蜍irx1-b重組蛋白
  • 貨號：
    CSB-EP650344XBE-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    有爪蟾蜍irx1-b重組蛋白
  • 貨號：
    CSB-BP650344XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    有爪蟾蜍irx1-b重組蛋白
  • 貨號：
    CSB-MP650344XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    irx1-b
  • Uniprot No.：
  • 別名：
    irx1-b; iro1-b; Iroquois-class homeodomain protein irx-1-B; Iroquois homeobox protein 1-B
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-462
  • 氨基酸序列
    MSFPQLGYPQ YLTAGQGAVY GGERPGVLAA AAAAAAAAGR PTGAELGSCP TAAVTSVLGM YASPYSSPNY SAFLPYTTDL TLFSQMGSQY ELKDNPGVHP ATFAAHTTPG YYPYGQFQYG DPGRPKNATR ESTSTLKAWL NEHRKNPYPT KGEKIMLAII TKMTLTQVST WFANARRRLK KENKVTWGAM GKEDDNIFGS DNEGDHEKNE DDEEIDLESI DIDKIDDNDG EQSNEEEDEK LDHFRHGEKV SLKKESEVMI PSSDGLKPKD SLSLGKECSD TSNTRIVSPG GQGNIQAPPH SKPKIWSLAE TATSPDGALK SSPPPSQANH TSPQMQHPAF LPSHGLYTCQ IGKFHNWTNG AFLTQSSLIN MRSLLGVNPH HAAHHNHHHL QAHQQSTLLA TNLGSLSSDR TPERTSPKHS DRENLPRTES PPQLKPSFQA VREKTFSQQE GTSRILTALP SA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts partially redundantly with other irx members in neural patterning. Required for formation of the posterior forebrain, midbrain, hindbrain, and to a lesser extent, spinal cord. Acts early in neural plate development to induce expression of some but not all proneural genes, and specify a neural precursor state. Also up-regulates repressors that prevent neuronal differentiation. Patterns the neuroectoderm in both the anterior/posterior and dorsal/ventral axes. Acts primarily as a transcriptional repressor during neural development, and binds to the bmp4 promoter to repress gene expression and thus mediate down-regulation of bmp4 by wnt signaling. Controls multiple processes through bmp4-repression including neural plate development, neural crest specification and Spemann organizer development. Involved in the specification of the preplacodal field at the anterior border of the neural plate. Regulates the genetic cascade of interactions that are necessary for positioning the isthmus organizer and the formation of the midbrain-hindbrain boundary. Required during at least two stages of pronephros kidney development; during neurula stages, maintains transcription of key renal genes to define the size and identity of the pronephric anlage, probably in part through regulation of bmp-signaling. Subsequently required for proper formation of the intermediate tubule segment of the pronephros. Acts principally as a transcriptional activator during pronephros development.
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    TALE/IRO homeobox family
  • 數(shù)據(jù)庫鏈接：

    KEGG: xla:735237

    UniGene: Xl.47737



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