在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Xenopus laevis DNA2-like helicase (dna2), partial

Recombinant Xenopus laevis DNA2-like helicase (dna2), partial

  • 中文名稱：
    有爪蟾蜍dna2重組蛋白
  • 貨號：
    CSB-YP854469XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    有爪蟾蜍dna2重組蛋白
  • 貨號：
    CSB-EP854469XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    有爪蟾蜍dna2重組蛋白
  • 貨號：
    CSB-EP854469XBE-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    有爪蟾蜍dna2重組蛋白
  • 貨號：
    CSB-BP854469XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    有爪蟾蜍dna2重組蛋白
  • 貨號：
    CSB-MP854469XBE
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    dna2; dna2lDNA replication ATP-dependent helicase/nuclease DNA2; DNA replication ATP-dependent helicase-like homolog) [Includes: DNA replication nuclease DNA2; EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2; EC 3.6.4.12)]
  • 種屬：
    Xenopus laevis (African clawed frog)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape fen1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit dna2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by the presence of RPA. Also involved in DNA replication checkpoint independently of Okazaki fragments processing. Possesses different enzymatic activities, such as single-stranded DNA (ssDNA)-dependent ATPase, 5'-3' helicase and endonuclease activities. While the ATPase and endonuclease activities are well-defined and play a key role in Okazaki fragments processing and DSB repair, the 5'-3' DNA helicase activity is subject to debate. According to various reports, the helicase activity is weak and its function remains largely unclear. Helicase activity may promote the motion of dna2 on the flap, helping the nuclease function.
  • 基因功能參考文獻：
    1. Data show that cleavage of free 5' DNA ends at clean double-strand breaks (DSBs) is mediated by DNA replication helicase/nuclease 2 (Dna2). PMID: 28981724
    2. Dna2 co-localizes in foci with RPA and is found in a complex with replication fork components And-1 and Mcm10. Dna2 interacts with the DSB repair and checkpoint proteins Nbs1 and ATM. PMID: 20237432
    3. Results provide strong evidence that xDNA2 is a major nuclease for the resection of DNA ends for homology-dependent DNA double-strand break repair in eukaryotes. PMID: 18820296
  • 亞細胞定位：
    Nucleus. Mitochondrion.
  • 蛋白家族：
    DNA2/NAM7 helicase family
  • 數(shù)據(jù)庫鏈接：

    KEGG: xla:378492

    UniGene: Xl.17390



主站蜘蛛池模板： 人妻av无码系列专区移动可看| 精品人妻伦九区久久aaa片| 日本妇人成熟免费| 中文字幕人妻a片免费看| 国产最新av在线播放不卡| 亚洲精品国偷拍自产在线麻豆| 鲁鲁鲁爽爽爽在线视频观看| 国产麻豆精品久久一二三| 樱花草在线社区www日本影院| 国产成人精品午夜福利不卡| 无码丰满熟妇juliaann与黑人| 久久综合狠狠色综合伊人| 日本中文一二区有码在线| 国产精品av一区二区三区不卡蜜 | 日日噜噜噜夜夜爽爽狠狠| 久久午夜无码鲁丝片秋霞| 久久精品国产男包| 我的性奴的肉玩具1一17心奴| www污污污抽搐喷潮com| 很色很爽很黄裸乳视频| 激情97综合亚洲色婷婷五| 玩弄丰满少妇xxxxx性多毛| 狠狠躁夜夜躁人人爽天天天天97| 亚洲欧洲日产国码韩国| 2020国产激情视频在线观看| 亚洲永久无码7777kkk| 免费无码av一区二区| 日日噜噜大屁股熟妇| 欧美真人性做爰一二区| 国产成人无码av在线播放dvd| 免费女人高潮流视频在线| 国产性夜夜春夜夜爽免费下载 | 男人的好看免费观看在线视频| 亚洲国产精品久久久久4婷婷| 国产精品成人一区二区三区| 中文字幕丰满乱孑伦无码专区| 越猛烈欧美xx00动态图| 亚洲人成在线观看网站无码| 无码人妻熟妇av又粗又大| 亚洲国产一区二区三区在观看| 亚洲综合久久无码色噜噜|