在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Vaccinia virus Protein F1 (VACWR040)

Recombinant Vaccinia virus Protein F1 (VACWR040)

  • 中文名稱：
    Recombinant Vaccinia virus Protein F1 (VACWR040)
  • 貨號：
    CSB-YP335035VAI
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Vaccinia virus Protein F1 (VACWR040)
  • 貨號：
    CSB-EP335035VAI
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Vaccinia virus Protein F1 (VACWR040)
  • 貨號：
    CSB-EP335035VAI-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Vaccinia virus Protein F1 (VACWR040)
  • 貨號：
    CSB-BP335035VAI
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Vaccinia virus Protein F1 (VACWR040)
  • 貨號：
    CSB-MP335035VAI
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    VACWR040
  • Uniprot No.：
  • 別名：
    VACWR040; F1LProtein F1
  • 種屬：
    Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-226
  • 氨基酸序列
    MLSMFMCNNI VDYVDDIDNG IVQDIEDEAS NNVDHDYVYP LPENMVYRFD KSTNILDYLS TERDHVMMAV RYYMSKQRLD DLYRQLPTKT RSYIDIINIY CDKVSNDYNR DMNIMYDMAS TKSFTVYDIN NEVNTILMDN KGLGVRLATI SFITELGRRC MNPVETIKMF TLLSHTICDD YFVDYITDIS PPDNTIPNTS TREYLKLIGI TAIMFATYKT LKYMIG
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in evading host innate immune response by inhibiting host inflammasome activation. Interacts with and inhibits NLR-mediated interleukin-1 beta/IL1B production in infected cells. At the host mitochondria, interacts with the BH3 domain of host BAK and prevents BAK from binding active BAX. In turn, host apoptosis is inhibited.
  • 基因功能參考文獻：
    1. The data demonstrate that E3 promotes F1 expression by blocking activation of the double-stranded RNA-activated protein kinase R (PKR). PMID: 29997208
    2. The N terminus of F1L is not involved in apoptosis inhibition and may act as a regulatory element in other signaling pathways in a manner reminiscent of other unstructured regulatory elements commonly found in mammalian prosurvival Bcl-2 members including Bcl-xL and Mcl-1. PMID: 27151220
    3. Authors demonstrate that during vaccinia virus infection, engagement of Bim and Bak by F1L is crucial for subversion of host cell apoptosis. PMID: 24850748
    4. F1L protein has a role in virulence of vaccinia virus by inhibiting inflammasome activation PMID: 23603272
    5. Viral N1 and F1 do not act as direct cellular Bax inhibitors to prevent Bax-induced cell death. PMID: 22013032
    6. analysis of structural determinants of caspase-9 inhibition by the vaccinia virus protein, F1L PMID: 21757755
    7. Data suggest that F1L replaces the antiapoptotic activity of Mcl-1 during vaccinia virus infection by interacting with Bak using highly divergent BH domains. PMID: 19955184
    8. in addition to interacting with the pro-apoptotic protein Bak, vaccinia F1L also functions to indirectly inhibit the activation of Bax, likely by interfering with the pro-apoptotic activity of BH3-only proteins such as BimL PMID: 17074758
    9. Results report that the crystal structure of F1L reveals a Bcl-2-like fold with an unusual N-terminal extension, and that the protein forms a novel domain-swapped dimer in which the alpha1 helix is the exchanged domain. PMID: 18551131
    10. Vaccinia growth factor stimulates an epidermal growth factor receptor-MEK-dependent pro-survival pathway that synergizes with F1L to counteract an infection-induced apoptotic pathway that predominantly involves the BH3-only protein Bad. PMID: 19388902

    顯示更多

    收起更多

  • 亞細胞定位：
    Host mitochondrion.
  • 蛋白家族：
    Poxviridae F1 protein family
  • 數據庫鏈接：

    KEGG: vg:3707497



主站蜘蛛池模板： 亚洲成av人影院无码不卡| 性xxxxx大片免费视频| а√天堂www在线а√天堂视频| 亚洲v国产v天堂a无码二区| 亚洲伊人成综合网2222| 欧美乱大交xxxxx潮喷l头像| 97免费公开在线视频| 免费无码作爱视频| 五月综合激情婷婷六月色窝| 18禁美女裸体免费网站| 在线观看黄a∨免费无毒网站| 亚洲一区爱区精品无码| 久久国产乱子伦免费精品| 亚洲精品97久久中文字幕无码| 亚洲影院天堂中文av色| 亚洲日韩av无码中文字幕美国 | 国产卡一卡二卡三| 国产精品乱码一区二区三区| 亚洲另类欧美小说图片区| 骚动漫十八禁在线观看| 无码aⅴ在线观看| 欧美最猛黑人xxxx黑人猛交| 在线视频国产网址你懂的| 蜜臀国产在线视频| 国产精品嫩草影院av| 无翼乌工口全彩肉肉无遮挡18| 亚洲熟妇av综合网五月| 精品一区二区三区无码免费直播| 欧美性欧美巨大黑白大战| 欧美性生交xxxxx无码久久久 | 欧美黑人巨大xxxxx视频| 人人妻人人玩人人澡人人爽| 少妇特殊按摩高潮惨叫无码| 亚洲欧美综合精品久久成人网| 性高湖久久久久久久久| 亚洲男同志网站| 九色综合九色综合色鬼| 欧美性猛交内射兽交老熟妇| 先锋影音最新色资源站| 亚洲综合在线视频自拍| 亚洲大码熟女在线|