在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Sheep Prostaglandin G/H synthase 1 (PTGS1), partial

  • 中文名稱:
    綿羊PTGS1重組蛋白
  • 貨號:
    CSB-YP018985SH1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    綿羊PTGS1重組蛋白
  • 貨號:
    CSB-EP018985SH1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    綿羊PTGS1重組蛋白
  • 貨號:
    CSB-EP018985SH1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    綿羊PTGS1重組蛋白
  • 貨號:
    CSB-BP018985SH1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    綿羊PTGS1重組蛋白
  • 貨號:
    CSB-MP018985SH1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    PTGS1; COX1; Prostaglandin G/H synthase 1; Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1
  • 種屬:
    Ovis aries (Sheep)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate, with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates arachidonate (AA, C20:4(n-6)) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide PGH2, the precursor of all 2-series prostaglandins and thromboxanes. This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins. The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
  • 基因功能參考文獻:
    1. mechanisms for the PGHS/AA/GSH-dependent formation of MDA, 15(S)-8-iso-prostaglandin F(2alpha) and other F(2)-isoprostanes PMID: 22982857
    2. The study compares crystal strucrures of COX1 in the presence and absence of different nonsteroidal antiinflammatory drugs and COX-2 inhibitors. PMID: 20669977
    3. regulation of expression of these enzymes is region-specific, suggesting that the activity of PGHS-1 & PGHS-2 is likely to be critical for brain development in the late-gestation ovine fetus. PMID: 19706338
    4. N-(3-hydroxyphenyl)arachidonoylamide is a substrate but not a inhibitor of PGHS-1. PMID: 19928795
    5. oxygenase reaction occurs by a sequential mechanism which most likely involves reversible abstraction of a hydrogen atom from the fatty acid prior to the trapping of the delocalized substrate radical by O2. PMID: 17355126

    顯示更多

    收起更多

  • 亞細胞定位:
    Endoplasmic reticulum membrane; Multi-pass membrane protein. Microsome membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Prostaglandin G/H synthase family
  • 數據庫鏈接:

    KEGG: oas:443551

    UniGene: Oar.445



主站蜘蛛池模板: 人妻三级日本三级日本三级极| 无码人妻精品一区二区三区东京热| 成人精品一区日本无码网站| 奇米在线7777在线精品| 久久久久久好爽爽久久| 色翁荡熄又大又硬又粗又动态图| 熟女丰满老熟女熟妇| 国产美女a做受大片观看| 中老年熟妇激情啪啪大屁股| 国产热re99久久6国产精品首页| 射死你天天日| 亚洲成a人片在线观看无码下载| 亚洲2020天天堂在线观看| 成人做爰www网站视频下载| 日本熟妇人妻xxxx| 中文字幕热久久久久久久| 国产精品久久人妻无码网站蜜臀| 亚洲丰满熟妇在线播放电影全集| 免费无码又爽又刺激网站| 精品人妻无码一区二区三区抖音| 人妻夜夜爽天天爽一区| 国产精品55夜色66夜色| 免费特级黄毛片| 国产成人无码综合亚洲日韩| 国产午夜精品一区二区三区老| 正在播放酒店约少妇高潮| 天堂а在线中文在线新版| 亚洲精品乱码久久久久久不卡| 免费无码av片在线观看国产| 久久www色情成人免费观看| 久久不见久久见免费影院 | 国产9 9在线 | 免费| 性色香蕉av久久久天天网| 亚洲熟女一区二区三区| 亚洲伊人丝袜精品久久| 人妻丰满av无码中文字幕| 亚洲a∨无码男人的天堂| 久久国产avjust麻豆| 欧美日韩一本无线码专区| 亚洲人成色77777| 国精产品一区一区三区有限在线|