在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Sheep Interleukin-1 beta (IL1B)

In Stock
  • 中文名稱:
    綿羊IL1B重組蛋白
  • 貨號:
    CSB-EP011614SH
  • 規(guī)格:
    ¥2328
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
  • Uniprot No.:
  • 別名:
    IL1BInterleukin-1 beta; IL-1 beta
  • 種屬:
    Ovis aries (Sheep)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    E.coli
  • 分子量:
    21.7kDa
  • 表達區(qū)域:
    114-266aa
  • 氨基酸序列
    AAVQSVKCKLQDREQKSLVLDSPCVLKALHLPSQEMSREVVFCMSFVQGEERDNKIPVALGIRDKNLYLSCVKKGDTPTLQLEEVDPKVYPKRNMEKRFVFYKTEIKNTVEFESVLYPNWYISTSQIEEKPVFLGRFRGGQDITDFRMETLSP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.
  • 基因功能參考文獻:
    1. Intravenous injection of SB203580 successfully inhibited synthesis of IL-1beta and reduced the production of IL-6 in the hypothalamus. PMID: 24995301
    2. Interleukin-1beta was increased only on the injured side of multifidus in disc disease. PMID: 24718080
    3. Inactivation of RhoA due to lack of prenylation leads to Rac1 activation and subsequent priming for IL-1beta secretion. PMID: 25107911
    4. RANTES-403 was significantly associated with the risk of developing diffuse-type gastric cancer in men and found a possible gene-gene interaction between RANTES and IL-1B polymorphisms in gastric cancer carcinogenesis. PMID: 24323564
    5. In vitro studies with IL-1-beta and TNF-alpha challenges, both proinflammatory cytokines resulted in elevated levels of CCL5 in conditioned media (p<0.01) PMID: 24468005
    6. These results showed that IL-1beta and IL-1 receptor types I and II were expressed in the ovine hypothalamus in response to lipopolysaccharide injection. PMID: 20345592
    7. These data are consistent with the effects of LPS on GH secretion originating through peripheral cytokine presentation to the pituitary, as well as a potential to act directly on selective populations of pituitary cells via CD14. PMID: 15899940
    8. plasma IL-1 beta, TNF-alpha and MCP-1 may potentially serve as markers to monitor prognosis of pregnancy toxaemia in ewes PMID: 17221363

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cytosol. Lysosome. Secreted, extracellular exosome. Secreted.
  • 蛋白家族:
    IL-1 family
  • 數(shù)據(jù)庫鏈接:

    KEGG: oas:443539

    UniGene: Oar.434



主站蜘蛛池模板: 后进式无遮挡啪啪摇乳动态图| 无码丰满熟妇| 业余 自由 性别 成熟视频 视频 | 九九热爱视频精品| 国产下药迷倒白嫩美女网站| 东京热久久综合久久88| 久久久久人妻精品一区二区三区| 人与狗精品aa毛片| 免费国产黄网站在线观看可以下载| 欧美日韩不卡合集视频| 国产男女性潮高清免费网站| 日产幕无线码三区在线| av区无码字幕中文色| 人妻换人妻a片爽麻豆| 国产成人无码18禁午夜福利p| 青青青国产免a在线观看| 国产精品一区二区av片| 国产交换配乱婬视频| 国产精品sp调教打屁股| 性色欲情网站| 国内精品久久久久久久电影视| 久久国产精品久久精品国产| k频道国产在线观看| 97人妻无码专区| 国产精品18禁污污网站| 国产精品一线二线三线| 亚洲精品国产精品制服丝袜| 久久久欧美精品激情| 中文字幕人妻第一区| 色偷偷av亚洲男人的天堂| 久久国产欧美日韩精品图片| 日本丰满岳乱妇在线观看| 久久丫精品系列| 人人妻人人狠人人爽| 久久成人影院精品99| 国产成人精品午夜福利不卡| 99国产精品99久久久久久| 亚洲精品第一国产综合精品| 无码啪啪熟妇人妻区| 久久国产精品波多野结衣av| 久久精品人人槡人妻人|