在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Sheep Interleukin 1β,IL-1β ELISA Kit

Sheep Interleukin 1β,IL-1β ELISA Kit

  • 中文名稱：
    綿羊白介素1β(IL-1β)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-E10115Sh
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3800/￥2500
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    綿羊白介素1β(IL-1β)酶聯(lián)免疫試劑盒（CSB-E10115Sh）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的IL1B含量。IL1B，即白細(xì)胞介素-1β，是一種重要的促炎細(xì)胞因子，參與先天免疫反應(yīng)。它由免疫和非免疫細(xì)胞在炎癥信號(hào)刺激下產(chǎn)生，通過(guò)炎癥小體激活和蛋白水解加工，與多種細(xì)胞因子協(xié)同作用，調(diào)節(jié)炎癥和免疫反應(yīng)，對(duì)腫瘤的發(fā)生、發(fā)展和轉(zhuǎn)移具有重要作用。試劑盒檢測(cè)范圍為15.6 pg/mL-1000 pg/mL，科研人員可借助定量分析感染模型、自身免疫疾病研究或藥物干預(yù)實(shí)驗(yàn)中不同生物樣本的IL - 1β濃度變化，為炎癥機(jī)制探索、免疫調(diào)控研究及生物制劑開發(fā)提供可靠數(shù)據(jù)支持。所有檢測(cè)結(jié)果僅用于科學(xué)研究目的。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說(shuō)明書。
  • 別名：
    IL1BInterleukin-1 beta ELISA Kit; IL-1 beta ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Ovis aries (Sheep)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍：
    15.6 pg/mL-1000 pg/mL
  • 靈敏度：
    3.9 pg/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Immunology
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of sheep IL-1β in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    　SampleSerum(n=4)
    1:1Average %86
    Range %83-90
    1:2Average %98
    Range %92-102
    1:4Average %100
    Range %96-104
    1:8Average %94
    Range %90-96
  • 回收率：
    The recovery of sheep IL-1β spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9490-97
    EDTA plasma (n=4)9794-99
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    10002.487 2.456 2.472 2.371
    5002.031 2.000 2.016 1.915
    2501.614 1.568 1.591 1.490
    1251.105 1.023 1.064 0.963
    62.50.703 0.689 0.696 0.595
    31.20.421 0.402 0.412 0.311
    15.60.275 0.262 0.269 0.168
    00.103 0.099 0.101 　
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

引用文獻(xiàn)

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.
  • 基因功能參考文獻(xiàn)：
    1. Intravenous injection of SB203580 successfully inhibited synthesis of IL-1beta and reduced the production of IL-6 in the hypothalamus. PMID: 24995301
    2. Interleukin-1beta was increased only on the injured side of multifidus in disc disease. PMID: 24718080
    3. Inactivation of RhoA due to lack of prenylation leads to Rac1 activation and subsequent priming for IL-1beta secretion. PMID: 25107911
    4. RANTES-403 was significantly associated with the risk of developing diffuse-type gastric cancer in men and found a possible gene-gene interaction between RANTES and IL-1B polymorphisms in gastric cancer carcinogenesis. PMID: 24323564
    5. In vitro studies with IL-1-beta and TNF-alpha challenges, both proinflammatory cytokines resulted in elevated levels of CCL5 in conditioned media (p<0.01) PMID: 24468005
    6. These results showed that IL-1beta and IL-1 receptor types I and II were expressed in the ovine hypothalamus in response to lipopolysaccharide injection. PMID: 20345592
    7. These data are consistent with the effects of LPS on GH secretion originating through peripheral cytokine presentation to the pituitary, as well as a potential to act directly on selective populations of pituitary cells via CD14. PMID: 15899940
    8. plasma IL-1 beta, TNF-alpha and MCP-1 may potentially serve as markers to monitor prognosis of pregnancy toxaemia in ewes PMID: 17221363

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cytosol. Lysosome. Secreted, extracellular exosome. Secreted.
  • 蛋白家族：
    IL-1 family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: oas:443539

    UniGene: Oar.434



主站蜘蛛池模板： 日韩av午夜在线观看| 99久久久国产精品消防器材| 日日av拍夜夜添久久免费| 黑人粗硬进入过程视频| 色情久久久av熟女人妻网站| 久久/这里只精品99re66| 色琪琪丁香婷婷综合久久| 国产又黄又湿无遮挡免费视频| 亚洲欧美综合区自拍另类| 日本极品少妇xxxx| 国产成人久久综合77777| 欧美人妻久久精品| 97爱亚洲综合成人| 狠狠色综合激情丁香五月| 羞羞色男人的天堂| 国产午夜无码片免费| 日本一卡二卡3卡四卡网站精品 | a v 在线视频 亚洲免费| 国产黑色丝袜在线看片不卡顿| 亚洲色婷婷一区二区三区| 精品无码久久久久国产动漫3d| av片日韩一区二区三区在线观看| 免费无码又爽又刺激软件下载直播| 国产精品va无码一区二区| 两根大肉大捧一进一出好爽视频| 中文无码高潮到痉挛在线视频| 成人午夜福利免费体验区| 性色做爰片在线观看ww | 免费国产乱理伦片在线观看| 欧美熟妇性xxxx交潮喷| 免费人成视频| 亚洲综合无码久久精品综合| 亚洲综合一区二区三区四区五区 | 色喜国模李晴超大尺度| 玩弄丰满熟妇xxxxx性60| 日韩欧美群交p片內射中文| 日韩成人无码中文字幕| 天堂aⅴ无码一区二区三区| 午夜人性色福利无码视频在线观看 | 成人影院yy111111| 菠萝蜜视频在线观看入口 |