在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Serine/threonine-protein kinase par-4 (par-4), partial

  • 中文名稱:
    秀麗隱桿線蟲par-4重組蛋白
  • 貨號:
    CSB-YP867092CXY
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲par-4重組蛋白
  • 貨號:
    CSB-EP867092CXY
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲par-4重組蛋白
  • 貨號:
    CSB-EP867092CXY-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲par-4重組蛋白
  • 貨號:
    CSB-BP867092CXY
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    秀麗隱桿線蟲par-4重組蛋白
  • 貨號:
    CSB-MP867092CXY
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    par-4
  • Uniprot No.:
  • 別名:
    par-4; Y59A8B.14; Serine/threonine-protein kinase par-4; EC 2.7.11.1
  • 種屬:
    Caenorhabditis elegans
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Controls the asymmetric cell division of the Q.p neuroblast lineage. Involved in mediating cell polarization via regulation of anillin family scaffold proteins. Phosphorylates and restricts the asymmetry effectors mex-5 and mex-6 to the anterior cytoplasm of the zygote and maintains these phosphorylations until fertilization. May phosphorylate par-1. Required for strd-1 localization to the cell cortex of early embryos and may be required for strd-1 protein stabilization. May regulate the integrity of the early embryonic cortex in a strd-1-dependent manner. Phosphorylates and regulates aak-2 in response to oxidative stress and during dauer development. May also play a role in motility, behavioral response, regulation of lifespan and dauer formation through this pathway. Required to establish germline stem cell (GSC) quiescence during dauer development. Acts downstream of unc-40 in dendrite outgrowth. May play a role in cell shedding during embryogenesis, probably by phosphorylating pig-1.
  • 基因功能參考文獻:
    1. the regulation of the cytoskeleton and cell polarity may contribute significantly to the tumour suppressor function of LKB1/par-4. PMID: 29907081
    2. We report here that din-1S is required in parallel to par-4/LKB1 signaling within the gonad to establish cell cycle quiescence during the onset of the dauer stage. PMID: 27260305
    3. PAR-4/LKB1 impinges on myosin via two pathways, an anillin-dependent pathway that also responds to the cullin CUL-5 and an anillin-independent pathway involving the kinase PIG-1/MELK. PMID: 26416962
    4. Par-4 activates PIG-1 by phosphorylation of T169. PMID: 23267054
    5. the serine-threonine kinase PAR-4 (LKB1) was selectively required for the activity of the UNC-40 pathway in dendrite outgrowth. PMID: 21186357
    6. The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior PMID: 18408008

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm, cell cortex.
  • 蛋白家族:
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, LKB1 subfamily
  • 組織特異性:
    Expressed in the gonads, oocytes and early embryos (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 久久久久国产精品人妻aⅴ牛牛| 国产成av人片久青草影院| 性色香蕉av久久久天天网| 国产精品一区二区 尿失禁| 午夜福利无码不卡在线观看| 少妇荡乳情欲办公室456视频| 久久婷婷色香五月综合缴缴情| 国产成人亚洲精品无码车a| 国产 日韩 中文字幕 制服| 国产人妻一区二区三区四区五区六| 久久丫精品忘忧草西安产品| 99久久国产宗和精品1上映| 婷婷五月日韩av永久免费| 国产百合互慰吃奶互揉视频| 欧美日韩亚洲国内综合网| 无码人妻精品一区二区三区久久久| 亚洲国产天堂久久久久久| 国产乱码一区二区三区爽爽爽 | 日日噜噜夜夜狠狠va视频v| 中文字幕乱码人妻二区三区| 欧美极品少妇性运交| 无码精品日韩专区| 中国熟妇人妻xxxxx| 污污内射久久一区二区欧美日韩| 男女啪啪做爰高潮免费网站| 丁香五月缴情在线| 国产精品自在在线午夜免费| 日本va欧美va欧美va精品| 国产成人免费爽爽爽视频| 欧洲美洲精品一区二区三区| 性按摩无码中文| 国产精品综合色区在线观看| 欧美成人午夜免费全部完| 亚洲综合最新无码专区| 亚洲成a∧人片在线播放无码| 中文字幕资源网| 老太婆性杂交欧美肥老太| 亚洲va久久久噜噜噜久久天堂| 精品一卡二卡三卡四卡网站 | 精品国产一区二区三区av片| 人妻在线无码一区二区三区|