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  4. Recombinant Serine/threonine-protein kinase par-1 (par-1), partial

Recombinant Serine/threonine-protein kinase par-1 (par-1), partial

  • 中文名稱：
    秀麗隱桿線蟲par-1重組蛋白
  • 貨號：
    CSB-YP880015CXY
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-1重組蛋白
  • 貨號：
    CSB-EP880015CXY
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-1重組蛋白
  • 貨號：
    CSB-EP880015CXY-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-1重組蛋白
  • 貨號：
    CSB-BP880015CXY
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲par-1重組蛋白
  • 貨號：
    CSB-MP880015CXY
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    par-1
  • Uniprot No.：
  • 別名：
    par-1; H39E23.1; Serine/threonine-protein kinase par-1; EC 2.7.11.1
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for cytoplasmic partitioning and asymmetric cell division in early embryogenesis. Phosphorylates and restricts the asymmetry effector mex-5 (and possibly also mex-6) to the anterior cytoplasm of the zygote. Regulates mes-1 expression during early embryogenesis. Critical role in postembryonic vulval morphogenesis. Involved in the establishment of neuronal polarity.
  • 基因功能參考文獻：
    1. Phosphorylation of FEZ1 by par-1 regulates its function in presynaptic protein trafficking. PMID: 27247180
    2. The par-1 protein is a possible cooperation and involvement in postembryo lethality, developmental timing, as well as SNARE protein trafficking. PMID: 24192838
    3. DNA replication is asymmetrically regulated in the two-cell stage embryo and the PAR-4 and PAR-1 polarity proteins dampen DNA replication dynamics specifically in the posterior blastomere. PMID: 24841566
    4. activity at the cell cortex is critical for mediating cell shape changes, cell surface composition, or cell signaling during vulval morphogenesis PMID: 12490197
    5. The par-1 kinase plays a major role in the antero-posterier axis formation and germline determinants polarisation. PMID: 15182702

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  • 亞細胞定位：
    Cytoplasm, cell cortex.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, SNF1 subfamily
  • 組織特異性：
    Asymmetrically localized to the posterior of the zygote before mitotic division, then differentially distributed to the germline precursor cells (at protein level).
  • 數據庫鏈接：

    KEGG: cel:CELE_H39E23.1

    STRING: 6239.H39E23.1d

    UniGene: Cel.6280



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