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  4. Recombinant Schizosaccharomyces pombe Uncharacterized protein C1921.07c (SPBC1921.07c, SPBC21D10.13)

Recombinant Schizosaccharomyces pombe Uncharacterized protein C1921.07c (SPBC1921.07c, SPBC21D10.13)

  • 中文名稱：
    龐貝裂殖酵母sgf29重組蛋白
  • 貨號：
    CSB-YP892020SXV
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母sgf29重組蛋白
  • 貨號：
    CSB-EP892020SXV
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母sgf29重組蛋白
  • 貨號：
    CSB-EP892020SXV-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母sgf29重組蛋白
  • 貨號：
    CSB-BP892020SXV
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母sgf29重組蛋白
  • 貨號：
    CSB-MP892020SXV
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    sgf29
  • Uniprot No.：
  • 別名：
    sgf29; SPBC1921.07c; SPBC21D10.13; SAGA-associated factor 29
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-244
  • 氨基酸序列
    MVRPINAEED VTSMWVKFHE SLNPIRSSLI KQEECYKTVD GDDNPIEERI KACDAGIQTS EEQKKELEHT MQSLEMIINV LEKANEKPVI TNSPLTRSRR NRGTSFTANT VTFTPGMSVA FKLPYTRHNE GGDWIQCIII KVTGEGAKQR FEVQDPEPDD DGNAGQIYKT TANHLIQIPA KGTPLPPISP KTNVLARYPE TTTFYRAEVI RTLPDGSCKL RFEGEEEVGK ETVVERHLVL EYNG
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Chromatin reader component of the transcription regulatory histone acetylation (HAT) complex SAGA. Sgf29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA complex, sgf29 is required to facilitate crosstalk between gcn5 acetyltransferase activity and H3K4me3 recognition. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac).
  • 基因功能參考文獻：
    1. Data indicate that Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator complex contains a separable subcomplex known as the histone acetyltransferase (HAT) module that contains the HAT, Gcn5, bound to Sgf29. PMID: 26401015
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    SGF29 family
  • 數據庫鏈接：


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