在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Schizosaccharomyces pombe Structural maintenance of chromosomes protein 6 (smc6), partial

Recombinant Schizosaccharomyces pombe Structural maintenance of chromosomes protein 6 (smc6), partial

  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-YP021818SXV
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-EP021818SXV
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-EP021818SXV-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-BP021818SXV
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-MP021818SXV
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    smc6
  • Uniprot No.：
  • 別名：
    smc6; rad18; SPCC5E4.06; Structural maintenance of chromosomes protein 6; DNA repair protein rad18
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis.
  • 基因功能參考文獻：
    1. Study shows that the Smc5/6-hinge complex binds preferentially to ssDNA and that this interaction is affected by both 'latch' and 'hub' mutations, suggesting a key role for these unique features in controlling DNA association by the Smc5/6 complex. PMID: 28134253
    2. Results provide evidence that Brc1 provides scaffolding functions linking gammaH2A, Rhp18, and Smc5/6 complex at damaged replication forks. PMID: 28784724
    3. The function of the SMC5/6 complex and its mammalian homologs in the cell cycle has not been clarified yet. PMID: 26743946
    4. Smc6 is a required for homologous recombination in S. pombe. PMID: 21976700
    5. Smc6 contributes to DNA repair in vivo by targeting the Smc5-6 complex to single-stranded DNA substrates created during the processes of homologous recombination and/or DNA replication. PMID: 22086171
    6. In an examination of the evolutionary conservation of the Nse3-Nse4 interactions, we find that several MAGE proteins can interact with at least one of the NSE4/EID proteins. PMID: 21364888
    7. there are two subcomplexes containing Rad18-Spr18-Nse2 and Nse1-Nse3-Rad62, which are probably bridged by a weaker interaction between Nse2 and Nse3 PMID: 15601840
    8. analysis of bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits in the Smc5-Smc6 DNA repair complex PMID: 17005570
    9. When replication forks collapse, Smc6 (formerly known as rad18) is required for the effective repair of lesions but not for the recruitment of recombination proteins. PMID: 17030601
    10. Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function. PMID: 17277362
    11. Nse1 RING-like motif is a protein-protein interaction domain required for Smc5-Smc6 holocomplex integrity and recruitment to, or retention at, DNA lesions PMID: 18667531
    12. Data suggest that localization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively. PMID: 18923417
    13. Smc5/6 is required to maintain stalled forks in a stable recombination-competent conformation primed for replication restart. PMID: 19158664
    14. Data show that defective cohesin removal is a major determinant of the mitotic lethality of Smc5-Smc6 mutants. PMID: 19528228

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    SMC family, SMC6 subfamily
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 情侣作爱视频网站| 私人家庭影院5777| 开心五月综合亚洲| 亚洲区小说区激情区图片区| 亚洲人成77777在线播放网站不卡| 国产成人无码午夜视频在线播放| 西欧free性满足hd老熟妇| 亚洲日韩国产一区二区三区| 欧美牲交a欧美牲交vdo18| 99精品国产丝袜在线拍国语| 国产成人a区在线观看视频| 国产成人精品一区二区三区视频 | 亚洲熟女综合一区二区三区| 国产精品久久人妻无码网站蜜臀 | 天天天天躁天天爱天天碰| 护士奶头又白又大又好摸视频| 国产乱妇乱子视频在播放| 精品亚洲国产成人av在线时间短的| 波多野结av在线无码中文 | 青草影院内射中出高潮-百度 | 四虎影视永久免费观看| 无码精品人妻一区二区三区人妻斩| 久久久久久久精品成人执小说一白| 国产新婚夫妇叫床声不断| 日本中文字幕有码在线视频| 久久99国产精一区二区三区| 国内精品综合久久久40p| 强行从后面挺进人妻| 大肉大捧一进一出好爽视频| 亚洲国产成人久久综合下载| 亚洲精品国产高清在线观看| 国产亚洲精品精品国产亚洲综合| 欧美日韩国产免费一区二区三区| 久久青青草原国产最新片完整| 免费观看又色又爽又湿的软件| 久久久无码一区二区三区| 中文字幕无码毛片免费看| 国产99视频精品免费视频6| 少妇人妻偷人精品视频| 国精产品一区一区三区有限公司杨 | 国产又色又爽又黄的视频在线观看|