在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Schizosaccharomyces pombe Structural maintenance of chromosomes protein 6 (smc6), partial

Recombinant Schizosaccharomyces pombe Structural maintenance of chromosomes protein 6 (smc6), partial

  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-YP021818SXV
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-EP021818SXV
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-EP021818SXV-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-BP021818SXV
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母smc6重組蛋白
  • 貨號：
    CSB-MP021818SXV
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    smc6
  • Uniprot No.：
  • 別名：
    smc6; rad18; SPCC5E4.06; Structural maintenance of chromosomes protein 6; DNA repair protein rad18
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks. Plays a critical role in meiosis.
  • 基因功能參考文獻：
    1. Study shows that the Smc5/6-hinge complex binds preferentially to ssDNA and that this interaction is affected by both 'latch' and 'hub' mutations, suggesting a key role for these unique features in controlling DNA association by the Smc5/6 complex. PMID: 28134253
    2. Results provide evidence that Brc1 provides scaffolding functions linking gammaH2A, Rhp18, and Smc5/6 complex at damaged replication forks. PMID: 28784724
    3. The function of the SMC5/6 complex and its mammalian homologs in the cell cycle has not been clarified yet. PMID: 26743946
    4. Smc6 is a required for homologous recombination in S. pombe. PMID: 21976700
    5. Smc6 contributes to DNA repair in vivo by targeting the Smc5-6 complex to single-stranded DNA substrates created during the processes of homologous recombination and/or DNA replication. PMID: 22086171
    6. In an examination of the evolutionary conservation of the Nse3-Nse4 interactions, we find that several MAGE proteins can interact with at least one of the NSE4/EID proteins. PMID: 21364888
    7. there are two subcomplexes containing Rad18-Spr18-Nse2 and Nse1-Nse3-Rad62, which are probably bridged by a weaker interaction between Nse2 and Nse3 PMID: 15601840
    8. analysis of bridging of the Smc5-Smc6 heads by the KLEISIN, Nse4, and non-Kleisin subunits in the Smc5-Smc6 DNA repair complex PMID: 17005570
    9. When replication forks collapse, Smc6 (formerly known as rad18) is required for the effective repair of lesions but not for the recruitment of recombination proteins. PMID: 17030601
    10. Brc1-mediated rescue of Smc5/6 deficiency: requirement for multiple nucleases and a novel Rad18 function. PMID: 17277362
    11. Nse1 RING-like motif is a protein-protein interaction domain required for Smc5-Smc6 holocomplex integrity and recruitment to, or retention at, DNA lesions PMID: 18667531
    12. Data suggest that localization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively. PMID: 18923417
    13. Smc5/6 is required to maintain stalled forks in a stable recombination-competent conformation primed for replication restart. PMID: 19158664
    14. Data show that defective cohesin removal is a major determinant of the mitotic lethality of Smc5-Smc6 mutants. PMID: 19528228

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    SMC family, SMC6 subfamily
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚洲欧美成人一区二区在线| 国产人成无码视频在线| 亚拍精品一区二区三区探花| 精品日产高清卡4卡5区别| 日本精品高清一区二区| 国产蜜臀av在线一区尤物| 中文字幕av久久激情亚洲精品| 日本久久综合久久鬼色| 国产精品中文久久久久久久| 欧美国产激情18| 日产日韩亚洲欧美综合下载| 99热网址最新获取域名| 毛片免费视频| 丰满少妇女裸体bbw| 国产成人8x人在线视频软件| 亚洲国产成人爱av网站| 少妇太爽了在线观看| 日本黄页网站免费观看| 爆乳护士一区二区三区在线播放| 中文字幕久久精品波多野结百度| 浓毛欧美老妇乱子伦视频| 国产色xx群视频射精| 日本一道综合久久aⅴ久久| 国产精品久久久久久tv| 爆乳2把你榨干哦ova在线观看| 亚洲 精品 综合 精品 自拍| 综合激情久久综合激情| 欧美另类 自拍 亚洲 图区| 特级做a爰片毛片免费看无码| 天天操夜夜操| 国产成人欧美日韩在线电影| 精品卡一卡二卡3卡高清乱码| 亚洲鲁丝片一区二区三区| 草草影院精品一区二区三区| 2019国产品在线视频| 蜜桃av抽搐高潮一区二区| 天美传媒精品1区2区3区| 强 暴 疼 哭 处 女 身子视频| 免费观看亚洲人成网站| 精品国产一区二区三区四区在线看| 中文字幕+乱码+中文字幕一区|