在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Schizosaccharomyces pombe Mitosis inhibitor protein kinase wee1 (wee1), partial

Recombinant Schizosaccharomyces pombe Mitosis inhibitor protein kinase wee1 (wee1), partial

  • 中文名稱：
    龐貝裂殖酵母wee1重組蛋白
  • 貨號：
    CSB-YP357135SXV
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母wee1重組蛋白
  • 貨號：
    CSB-EP357135SXV
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母wee1重組蛋白
  • 貨號：
    CSB-EP357135SXV-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母wee1重組蛋白
  • 貨號：
    CSB-BP357135SXV
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母wee1重組蛋白
  • 貨號：
    CSB-MP357135SXV
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    wee1; SPCC18B5.03Mitosis inhibitor protein kinase wee1; EC 2.7.10.2; P107 protein kinase homolog
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Protein kinase that acts both on serines and on tyrosines. It acts as a dosage-dependent negative regulator of entry into mitosis (G2 to M transition). Phosphorylates and inhibits cdc2.
  • 基因功能參考文獻：
    1. Regulation of Wee1 localization around the spindle pole body during the G2/M transition is important for proper mitotic entry and progression. PMID: 21233285
    2. in fission yeast Wee1 is the major inhibitory kinase regulating CDK activity in S phase. PMID: 26918805
    3. This cell cycle arrest is dependent on the Wee1 tyrosine kinase inhibiting the key cell cycle regulator, CDK1/Cdc2. Mutant cells lacking Wee1 are not arrested at G2 upon glucose limitation and lose viability faster than the wild-type cells under glucose-depleted quiescent conditions, suggesting that this cell cycle arrest is required for extension of chronological lifespan PMID: 26804466
    4. Wee1 phosphorylates Cdc2 Tyr15 which leads to replication slowdown in the fission yeast under nitrosative stress. PMID: 26006103
    5. Dnt1 regulates G2/M transition and cytokinesis by downregulating Wee1 kinase. PMID: 24006256
    6. Substitution of a conserved methionine residue to phenylalanine in Plo1, Orb5 and Wee1 kinases increased the sensitivities to ATP analogues. PMID: 23986474
    7. Data show that the protein Skb1 interacted with both Cdr1 and the Cdr1 inhibitory target Wee1. PMID: 23615447
    8. Sid2 activation midway through G2 phase promotes Fin1 phosphorylation and mitotic commitment throught pom1/Wee1 cell geometry network. PMID: 22684255
    9. in fission yeast Cpc2/RACK1 positively regulates from the ribosome the mitotic onset by modulating both the protein levels and the activity of Wee1 PMID: 20974849
    10. The changed division response (Cdr) kinases Cdr1 and Cdr2 are negative regulators of Wee1 and they are required for the Tra1-dependent alterations to Wee1 function. PMID: 20194963
    11. findings demonstrate that G2 arrest induced by HIV-1 Vpr is also associated with increase in phosphorylation & amount of Wee1 in a Chk1/Cds1-independent manner; Rad24 appears to contribute to Vpr-induced G2 arrest by elevating Wee1 expression PMID: 16968670

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, WEE1 subfamily
  • 數據庫鏈接：


主站蜘蛛池模板： 欧美日本特级婬片视频| 日韩精品av一区二区三区| 亚洲国产欧美一区二区好看电影| 国语高潮无遮挡无码免费看| 中文字幕日韩人妻无码 | 黑森林福利视频导航| 18禁止进入1000部高潮网站| 天堂av无码大芭蕉伊人av不卡| 亚洲成_人网站图片| 少妇激情一区二区三区视频小说| 蜜臀av色欲a片无码精品一区| 老师黑色丝袜被躁翻了av| 亚洲五月色丁香婷婷婷| 又色又爽又黄的视频网站| 亚洲永久网址在线观看| 欧美综合精品久久久久成人影院| 97夜夜澡人人爽人人模人人喊| 18禁免费无码无遮挡不卡网站| 色噜噜av男人的天堂| 2018国产精华国产精品| 一本一道av中文字幕无码| 最近中文字幕mv在线视频2018| 色插图午夜影院| 成人性做爰aaa片免费看| 国产av亚洲aⅴ一区二区 | 人妻少妇伦在线麻豆m电影| 97久久精品人人槡人妻人| 人妻丰满av无码久久不卡| 亚洲小说图区综合在线| 亚洲偷精品国产五月丁香麻豆| 无码少妇一区二区性色av| 风流老熟女一区二区三区| 日本亚洲欧美高清专区vr专区 | 日本毛茸茸的丰满熟妇| 欧美xxxx黑人又粗又长| 亚洲日韩国产成网在线观看| 性欧美性另类巨大| 人妻av无码系列一区二区三区 | 日本xxxx裸体xxxx视频大全| 粗大猛烈进出高潮视频免费看| 欧美又粗又大又硬又长又爽视频 |