在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Rat H-2 class II histocompatibility antigen gamma chain (Cd74), partial

Recombinant Rat H-2 class II histocompatibility antigen gamma chain (Cd74), partial

  • 中文名稱：
    Recombinant Rat H-2 class II histocompatibility antigen gamma chain(Cd74),partial
  • 貨號：
    CSB-YP004956RA
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat H-2 class II histocompatibility antigen gamma chain(Cd74),partial
  • 貨號：
    CSB-EP004956RA-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat H-2 class II histocompatibility antigen gamma chain(Cd74),partial
  • 貨號：
    CSB-BP004956RA
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat H-2 class II histocompatibility antigen gamma chain(Cd74),partial
  • 貨號：
    CSB-MP004956RA
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Cd74; H-2 class II histocompatibility antigen gamma chain; Ia antigen-associated invariant chain; Ii; MHC class II-associated invariant chain; CD antigen CD74) [Cleaved into: Class-II-associated invariant chain peptide; CLIP)]
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44.; Binds to the peptide-binding site of MHC class II alpha/beta heterodimers forming an alpha-beta-CLIP complex, thereby preventing the loading of antigenic peptides to the MHC class II complex until its release by HLA-DM in the endosome.; Stabilizes the conformation of mature CTSL by binding to its active site and serving as a chaperone to help maintain a pool of mature enzyme in endocytic compartments and extracellular space of antigen-presenting cells (APCs).
  • 基因功能參考文獻：
    1. cytokine MIF was able to elicit inflammatory response of astrocytes through interaction with CD74 receptor, and activation of ERK was necessary for the intracellular signal transduction. PMID: 27926507
    2. Methylglyoxal induced gene expression of CD74 in the in the diabetic retina. PMID: 24974304
    3. Macrophage migration inhibitory factor(MIF)/CD74 interaction induces upregulation of cyclooxygenase (COX)-2 and prostaglandin E2 secretion in primary rodent microglia. PMID: 21802455
    4. Data indicate that intraluminal macrophage migration inhibitory factor, released from urothelial cells as a consequence of substance P treatment, interacts with urothelial cell-surface CD74. PMID: 19325914
    5. Intraluminal blockade of cell-surface CD74 and glucose regulated protein 78 prevents substance P-induced bladder inflammatory changes in the rat PMID: 19503733

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform Long]: Late endosome. Lysosome.; Cell membrane; Single-pass type II membrane protein. Endoplasmic reticulum membrane. Golgi apparatus, trans-Golgi network. Endosome. Lysosome.
  • 數據庫鏈接：


主站蜘蛛池模板： 人与嘼av免费| 欧美亚洲色欲色一欲www| 成人性无码专区免费视频| 国产ww久久久久久久久久| 色播久久人人爽人人爽人人片av| 亚洲欧美国产成人综合欲网| 中国少妇内射xxxhd| 一本无码人妻在中文字幕| 四虎av永久在线精品免费观看| 亚洲夜夜性无码| 亚洲日韩国产一区二区三区 | 久久久精品妇女99| 日本又黄又爽又色又刺激的视频 | 在线综合亚洲欧洲综合网站| 国产亚洲精品国产福利你懂的| 亚洲精品国产一区黑色丝袜| 久久无码人妻精品一区二区三区| 日韩国产高清一区二区| 国产无遮挡又黄又爽动态图| 国产精品无码av一区二区三区 | 亚洲天堂2017无码| 日本一区二区无卡高清视频| 亚洲 欧美 唯美 国产 伦 综合| 天堂8在线新版官网| 玩弄漂亮少妇高潮白浆| 国语自产偷拍精品视频蜜芽| 国产一区日韩二区欧美三区| 国产suv精品一区二区883| 日韩人妻无码精品专区906188| 国产成人av 综合 亚洲| 中文字幕色av一区二区三区| 97成人精品国语自产拍| 国产在线高清视频无码| 国产男女猛烈无遮挡免费视频| 人人妻人人妻人人片av| 日韩成人无码v清免费| 亚洲精品乱码久久久久久自慰| 一区二区乱子伦在线播放| 色欲av永久无码精品无码| 精品国产高清毛片a片看| 亚洲精品蜜夜内射|