在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saimiri sciureus Proto-oncogene tyrosine-protein kinase LCK (LCK), partial

  • 中文名稱:
    Recombinant Saimiri sciureus Proto-oncogene tyrosine-protein kinase LCK(LCK) ,partial
  • 貨號(hào):
    CSB-YP853302SWD
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Saimiri sciureus Proto-oncogene tyrosine-protein kinase LCK(LCK) ,partial
  • 貨號(hào):
    CSB-EP853302SWD
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Saimiri sciureus Proto-oncogene tyrosine-protein kinase LCK(LCK) ,partial
  • 貨號(hào):
    CSB-EP853302SWD-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Saimiri sciureus Proto-oncogene tyrosine-protein kinase LCK(LCK) ,partial
  • 貨號(hào):
    CSB-BP853302SWD
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Saimiri sciureus Proto-oncogene tyrosine-protein kinase LCK(LCK) ,partial
  • 貨號(hào):
    CSB-MP853302SWD
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    LCKProto-oncogene tyrosine-protein kinase LCK; EC 2.7.10.2; Lymphocyte cell-specific protein-tyrosine kinase; p56-LCK
  • 種屬:
    Saimiri sciureus (Common squirrel monkey)
  • 蛋白長(zhǎng)度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Non-receptor tyrosine-protein kinase that plays an essential role in the selection and maturation of developing T-cells in the thymus and in the function of mature T-cells. Plays a key role in T-cell antigen receptor (TCR)-linked signal transduction pathways. Constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors. Association of the TCR with a peptide antigen-bound MHC complex facilitates the interaction of CD4 and CD8 with MHC class II and class I molecules, respectively, thereby recruiting the associated LCK protein to the vicinity of the TCR/CD3 complex. LCK then phosphorylates tyrosine residues within the immunoreceptor tyrosine-based activation motifs (ITAM) of the cytoplasmic tails of the TCR-gamma chains and CD3 subunits, initiating the TCR/CD3 signaling pathway. Once stimulated, the TCR recruits the tyrosine kinase ZAP70, that becomes phosphorylated and activated by LCK. Following this, a large number of signaling molecules are recruited, ultimately leading to lymphokine production. LCK also contributes to signaling by other receptor molecules. Associates directly with the cytoplasmic tail of CD2, which leads to hyperphosphorylation and activation of LCK. Also plays a role in the IL2 receptor-linked signaling pathway that controls the T-cell proliferative response. Binding of IL2 to its receptor results in increased activity of LCK. Is expressed at all stages of thymocyte development and is required for the regulation of maturation events that are governed by both pre-TCR and mature alpha beta TCR. Phosphorylates other substrates including RUNX3, PTK2B/PYK2, the microtubule-associated protein MAPT, RHOH or TYROBP.
  • 亞細(xì)胞定位:
    Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol.
  • 蛋白家族:
    Protein kinase superfamily, Tyr protein kinase family
  • 組織特異性:
    Expressed specifically in lymphoid cells.


主站蜘蛛池模板: 亚洲精品无码久久久久av麻豆| 伊人情人综合网| 日本老熟妇毛茸茸| 亚洲国精产品一二二线| 精品av国产一二三四区| 久久亚洲中文无码咪咪爱| 国产午夜片无码区在线观看| 亚洲电影在线观看| 无码精品国产一区二区三区免费| 国产精品96久久久久久av网址| 免费午夜理论不卡| 久久97超碰色中文字幕总站| 国产av无码国产av毛片| 亚洲日韩中文字幕一区| 国产亚洲视频在线观看播放| 曰批免费视频播放免费直播| 无码三级中文字幕在线观看| 国产98色在线 | 日韩| 国产成a人亚洲精品无码樱花| 国产精品 自在自线| 欧美日韩无砖专区一中文字| 国产交换配乱婬视频| 精品久久久久久中文字幕| 性色a∨人人爽网站hdkp885| 国产欧美日韩亚洲精品专区| 日韩99在线 | 中文| 亚洲国产精品久久久久婷婷老年 | 狠狠色综合激情丁香五月| 少妇内射兰兰久久| 国产亚洲精品福利视频在线观看| 精品人妻系列无码专区久久| 精精国产xxxx视频在线| 亚洲第一网站男人都懂| 国产片a国产片免费看视频| 国产激情高中生呻吟视频 | 午夜精品久久久久久久无码| 骚片av蜜桃精品一区| 免费人成又黄又爽的视频| 国产伦精品一区二区三区免.费| 国产日韩一区二区三免费高清| 国产精品欧美福利久久|