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  4. Recombinant Saccharomyces cerevisiae Suppressor of mar1-1 protein (SUM1), partial

Recombinant Saccharomyces cerevisiae Suppressor of mar1-1 protein (SUM1), partial

  • 中文名稱：
    釀酒酵母SUM1重組蛋白
  • 貨號：
    CSB-YP343995SVG
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母SUM1重組蛋白
  • 貨號：
    CSB-EP343995SVG
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母SUM1重組蛋白
  • 貨號：
    CSB-EP343995SVG-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母SUM1重組蛋白
  • 貨號：
    CSB-BP343995SVG
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母SUM1重組蛋白
  • 貨號：
    CSB-MP343995SVG
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SUM1
  • Uniprot No.：
  • 別名：
    SUM1; YDR310C; D9740.19; Suppressor of mar1-1 protein; SUM1-1 protein
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    DNA-binding protein that specifically binds the regulatory region of middle sporulation genes (MSE). Required for the repression of middle sporulation genes during vegetative growth. Represses expression via the recruitment of histone deacetylase HST1.
  • 基因功能參考文獻：
    1. In the absence of Set1, there is loss of the DNA-binding transcriptional regulator Sum1 and the associated histone deacetylase Hst1 from chromatin in a locus-specific manner PMID: 29066473
    2. high copies of Sum1p stabilize microtubules against a variety of adverse and destabilizing conditions like mutations, low temperatures and drugs. PMID: 22285862
    3. Sum1p is functionally connected to the origin recognition complex. PMID: 15988008
    4. Data indicate that Sum1-1p can increase the stability of Sir-dependent silent chromatin. PMID: 16406069
    5. isoleucine enabled Sum1-1p to associate with the origin recognition complex (ORC) and accumulate near ORC binding sites PMID: 18268008
    6. The mating-type regulatory function of Sum1 was conserved in S. cerevisiae. PMID: 18559484
    7. Sum1 was found to functioned in initiation as a component of the Sum1/Rfm1/Hst1 complex, implying a role for histone deacetylation in origin activity. PMID: 18990212
    8. Data show that the Sum1 repressor can be removed from middle promoters in meiotic cells independent of Ndt80 expression, and that this process requires the phosphorylation of Sum1 by Ime2. PMID: 19528232
    9. Midsporulation elements in the SPS18-SPS19 promoter region are targeted by the Sum1p repressor in association with Hst1p and Rfm1p. PMID: 19583587

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  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：

    KEGG: sce:YDR310C

    STRING: 4932.YDR310C



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