在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae Protein SUS1 (SUS1)

Recombinant Saccharomyces cerevisiae Protein SUS1 (SUS1)

  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-YP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-EP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-EP747670SVG-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-BP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-MP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SUS1
  • Uniprot No.：
  • 別名：
    SUS1; YBR111W-A; Transcription and mRNA export factor SUS1
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-96
  • 氨基酸序列
    MTMDTAQLKS QIQQYLVESG NYELISNELK ARLLQEGWVD KVKDLTKSEM NINESTNFTQ ILSTVEPKAL EMVSDSTRET VLKQIREFLE EIVDTQ
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is involved in RNA polymerase II-dependent regulation of approximately 10% of yeast genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8). Within the SAGA complex, participates in a subcomplex with SGF11, SGF73 and UBP8 required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), by association with components of the nuclear mRNA export machinery (MEX67-MTR2 and SUB2) in the nucleoplasm and the nucleoporin NUP1 at the nuclear basket. TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. SUS1 has also a role in mRNP biogenesis and maintenance of genome integrity through preventing RNA-mediated genome instability. Has a role in response to DNA damage induced by methyl methane sulfonate (MMS) and replication arrest induced by hydroxyurea. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
  • 基因功能參考文獻(xiàn)：
    1. Study provides support for a model in which SAGA/TREX-2 factor Sus1 acts as a global transcriptional regulator in yeast but has differential activity at yeast genes as a function of their transcription rate or during stress conditions. PMID: 29598828
    2. results provide solid evidence for a role of Sus1 in negatively regulating telomere length through the modulation of H2BK123 mono-ubiquitination and its interaction with the nuclear pore complex PMID: 29116388
    3. Exon three-way junction structure exerted a role in SUS1 transcript metabolism that includes splicing and transcript degradation. PMID: 29966763
    4. Examination of pre-mRNA splicing efficiency in these mutants reveals the requirement of Npl3 methylation for the efficient splicing of SUS1 intron 1, but not of ECM33 or ASC1. PMID: 28392442
    5. Study described the formation of mutually exclusive complexes of ENY2 with insulator proteins and Sgfl1-a component of the SAGA complex, direct binding partner for ENY2 PMID: 27417714
    6. demonstrates that I2 structure is relevant for SUS1 expression, and that this effect is likely exerted through modulation of splicing PMID: 26546116
    7. the pattern of SUS1 splicing changes in response to environmental change such as temperature elevation, and the retained intron product is subject to nonsense-mediated decay. PMID: 21749978
    8. Nonsense-mediated decay pathway and the splicing factor Mud2 both play a role in SUS1 expression. PMID: 21749979
    9. splicing of one pre-messenger RNA, SUS1, a component of the histone H2B ubiquitin protease machinery, is essential for establishing the proper modification state of chromatin PMID: 19561118

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus, nucleoplasm. Cytoplasm, P-body.
  • 蛋白家族：
    ENY2 family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 麻豆果冻国产剧情av在线播放| 国产一三四2021不卡| 深夜福利啪啪片| 亚洲精品一区二区三区麻豆| 顶级欧美熟妇高潮xxxxx| 国产农村妇女毛片精品久久| 少妇性l交大片| 亚洲精品欧美综合一区二区| 亚洲一区二区三区在线网址| 性一交一乱一伦一色一情孩交| 女人被弄到高潮的免费视频 | 麻豆精品传媒一二三区艾秋| 污污污www精品国产网站| 国产乱妇乱子在线播放视频| 亚洲精品综合一区二区三| 男人边吃奶边做好爽免费视频| 无码人妻久久久一区二区三区 | 久久精品无码一区二区app| 国产 日韩 另类 视频一区| 亚洲精品久久久久中文字幕| 国产精品国产免费无码专区不卡| 久久亚洲国产精品亚洲老地址| 日日日日做夜夜夜夜无码| 免费欧洲美女牲交视频| 亚洲一区二区女搞男| 久久国产色欲av38| 精品人妻无码区二区三区| 亚洲免费人成在线视频观看| 亚洲欧美日韩国产综合点击进入| 亚洲国产精品无码专区影院| 女性高爱潮视频| 亚洲成a人片在线观看无码下载| 香港曰本韩国三级网站| 极品人妻videosss人妻| 国模少妇一区二区三区| 中文字幕无码精品三级在线电影| 欧美性猛交xxxx乱大交蜜桃| 性生交大全免费看| 宅男宅女精品国产av天堂| 久久精品一区二区av999| 狠狠热精品免费视频|