在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae Protein SUS1 (SUS1)

Recombinant Saccharomyces cerevisiae Protein SUS1 (SUS1)

  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-YP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-EP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-EP747670SVG-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-BP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母SUS1重組蛋白
  • 貨號：
    CSB-MP747670SVG
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    SUS1
  • Uniprot No.：
  • 別名：
    SUS1; YBR111W-A; Transcription and mRNA export factor SUS1
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-96
  • 氨基酸序列
    MTMDTAQLKS QIQQYLVESG NYELISNELK ARLLQEGWVD KVKDLTKSEM NINESTNFTQ ILSTVEPKAL EMVSDSTRET VLKQIREFLE EIVDTQ
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is involved in RNA polymerase II-dependent regulation of approximately 10% of yeast genes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction (SPT3, SPT8 and SPT20) and promoter selectivity, interaction with transcription activators (GCN5, ADA2, ADA3 and TRA1), and chromatin modification through histone acetylation (GCN5) and deubiquitination (UBP8). Within the SAGA complex, participates in a subcomplex with SGF11, SGF73 and UBP8 required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket), by association with components of the nuclear mRNA export machinery (MEX67-MTR2 and SUB2) in the nucleoplasm and the nucleoporin NUP1 at the nuclear basket. TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. SUS1 has also a role in mRNP biogenesis and maintenance of genome integrity through preventing RNA-mediated genome instability. Has a role in response to DNA damage induced by methyl methane sulfonate (MMS) and replication arrest induced by hydroxyurea. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
  • 基因功能參考文獻(xiàn)：
    1. Study provides support for a model in which SAGA/TREX-2 factor Sus1 acts as a global transcriptional regulator in yeast but has differential activity at yeast genes as a function of their transcription rate or during stress conditions. PMID: 29598828
    2. results provide solid evidence for a role of Sus1 in negatively regulating telomere length through the modulation of H2BK123 mono-ubiquitination and its interaction with the nuclear pore complex PMID: 29116388
    3. Exon three-way junction structure exerted a role in SUS1 transcript metabolism that includes splicing and transcript degradation. PMID: 29966763
    4. Examination of pre-mRNA splicing efficiency in these mutants reveals the requirement of Npl3 methylation for the efficient splicing of SUS1 intron 1, but not of ECM33 or ASC1. PMID: 28392442
    5. Study described the formation of mutually exclusive complexes of ENY2 with insulator proteins and Sgfl1-a component of the SAGA complex, direct binding partner for ENY2 PMID: 27417714
    6. demonstrates that I2 structure is relevant for SUS1 expression, and that this effect is likely exerted through modulation of splicing PMID: 26546116
    7. the pattern of SUS1 splicing changes in response to environmental change such as temperature elevation, and the retained intron product is subject to nonsense-mediated decay. PMID: 21749978
    8. Nonsense-mediated decay pathway and the splicing factor Mud2 both play a role in SUS1 expression. PMID: 21749979
    9. splicing of one pre-messenger RNA, SUS1, a component of the histone H2B ubiquitin protease machinery, is essential for establishing the proper modification state of chromatin PMID: 19561118

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus, nucleoplasm. Cytoplasm, P-body.
  • 蛋白家族：
    ENY2 family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚洲国产精品久久久久婷婷软件| 亚洲成av人片天堂网站| 老子影院午夜伦手机不四虎卡| 中文成人无字幕乱码精品区| 国产乡下妇女做爰| 婷婷色中文字幕综合在线| 国产日韩制服丝袜第一页| 国产精品久久久久久久伊一| 国产精品视频一区二区噜噜| 精品国产一区二区三区四区阿崩| 人人鲁人人莫人人爱精品 | 性生交大片免费看女人按摩摩| 日本熟妇乱人伦xxxx| 国产av福利久久| 奇米777四色影视在线看| 日本va欧美va欧美va精品 | 一本大道无码人妻精品专区| 天堂一区人妻无码| 久久久久99精品成人片牛牛影视| 成 人 社区在线视频| 尤物精品国产第一福利网站| 污污污www精品国产网站| 男人撕开奶罩揉吮奶头视频| 亚洲综合色婷婷六月丁香宅男大增| 曰本女人牲交高潮视频| 国产成人无码一二三区视频| 精品亚洲一区二区三区四区五区 | 亚洲熟妇av午夜无码不卡| 国产成人av性色在线影院色戒| 免费观看性欧美大片无片| 日产一区日产2区| 亚洲精品久久午夜无码一区二区| 波多老师无码av中字专区| 丰满少妇呻吟高潮经历| 日产精品一区二区| 双腿张开被9个黑人调教影片| 国产麻豆精品精东影业av网站 | 天天av天天翘天天综合网| 成人欧美一区二区三区1314| 国产 高潮 抽搐 正在播放 | 欧美国产成人精品一区二区三区|