在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Saccharomyces cerevisiae Proteasome activator BLM10 (BLM10), partial

Recombinant Saccharomyces cerevisiae Proteasome activator BLM10 (BLM10), partial

  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Proteasome activator BLM10(BLM10) ,partial
  • 貨號：
    CSB-YP337453SVG
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Proteasome activator BLM10(BLM10) ,partial
  • 貨號：
    CSB-EP337453SVG
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Proteasome activator BLM10(BLM10) ,partial
  • 貨號：
    CSB-EP337453SVG-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Proteasome activator BLM10(BLM10) ,partial
  • 貨號：
    CSB-BP337453SVG
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Saccharomyces cerevisiae Proteasome activator BLM10(BLM10) ,partial
  • 貨號：
    CSB-MP337453SVG
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    BLM10
  • Uniprot No.：
  • 別名：
    BLM10; BLM3; YFL007W; YFL006WProteasome activator BLM10; Bleomycin resistance protein BLM10
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Associated component of the proteasome that specifically recognizes acetylated histones and promotes ATP- and ubiquitin-independent degradation of core histones during DNA damage response. Recognizes and binds acetylated histones via its bromodomain-like (BRDL) region and activates the proteasome by opening the gated channel for substrate entry. Binds to the core proteasome via its C-terminus, which occupies the same binding sites as the proteasomal ATPases, opening the closed structure of the proteasome via an active gating mechanism. Involved in DNA damage response in somatic cells: binds to acetylated histones and promotes degradation of histones following DNA double-strand breaks.
  • 基因功能參考文獻：
    1. data are consistent with a model in which Blm10 proteasome-mediated turnover of Dnm1 is required for the maintenance of mitochondrial function PMID: 24604417
    2. Blm10 represents the first proteolytic core particle-dedicated nuclear import receptor in yeast. PMID: 23982732
    3. Data propose that the cellular function of Blm10 is based on central core of the proteasome association and activation to promote the degradation of proteasome substrates. PMID: 22025621
    4. Blm10 functions in a proteasome-related process and it is required for the maintenance of mitochondrial function. PMID: 20227375
    5. Synthetic interactions between blm10Delta and other mutations that impair proteasome function show that Blm10 functions together with proteasomes in vivo PMID: 15778719
    6. Data show that Blm10 binds in a defined orientation to both ends of the 20 S particle and contacts all the proteasome alpha subunits. PMID: 16952374
    7. Blm10 and the 19 S activator with Pre4 have a partially redundant function in stabilizing nascent 20 S proteasomes and in promoting their activation PMID: 17911101
    8. Blm10 distinguishes between gate conformations and regulates the activation of core particles. PMID: 18927584

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    BLM10 family
  • 數據庫鏈接：

    KEGG: sce:YFL007W

    STRING: 4932.YFL007W



主站蜘蛛池模板： 欧洲成人一区二区三区| 亚洲欧洲国产成人综合在线观看| 玩超薄丝袜人妻的经历| 亚洲狠狠婷婷综合久久蜜芽| 午夜福利体验免费体验区| 日韩免费无码人妻波多野| 无码潮喷a片无码高潮视频| 特黄特色大片免费播放| 中文人妻av久久人妻18| 国产精品美女久久久久久2021| 亚洲性无码av在线dvd| 99久久婷婷国产综合精品青草免费| 亚洲深深色噜噜狠狠爱网站| 亚洲中文字幕伊人久久无码| 狠狠做五月深爱婷婷伊人| 国产精品人妻一区二区三区四| 麻豆国产尤物av尤物在线观看| 一本一本久久a久久综合精品| 激情按摩系列片aaaa| 天码av无码一区二区三区四区| 亚洲精品1卡2卡三卡4卡乱码| 最新国产精品无码| 亚洲精品www久久久| 成人精品一区二区三区中文字幕| 婷婷网亚洲色偷偷男人的天堂| 欧美两根一起进3p在线观看| 亚洲精品夜夜夜| 狼色精品人妻在线视频免费| 未满十八18禁止午夜免费网站| 苍井空一区二区波多野结衣av| 噜噜色综合噜噜色噜噜色| 日韩综合亚洲色在线影院| 亚洲精品中文字幕一区二区三区| 日日噜噜噜夜夜爽爽狠狠| 亚洲精品人成网线在线播放va| 人成午夜免费大片| 国产偷人爽久久久久久老妇app| 欧美粗大猛烈老熟妇| 色欲来吧来吧天天综合网| 暖暖视频日本| 成 人 在 线 免费观看|