Recombinant Saccharomyces cerevisiae Probable E3 ubiquitin-protein ligase HUL5 (HUL5), partial

中文名稱：

釀酒酵母HUL5重組蛋白
貨號：

CSB-YP346047SVG
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母HUL5重組蛋白
貨號：

CSB-EP346047SVG
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母HUL5重組蛋白
貨號：

CSB-EP346047SVG-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母HUL5重組蛋白
貨號：

CSB-BP346047SVG
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母HUL5重組蛋白
貨號：

CSB-MP346047SVG
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

HUL5
Uniprot No.：

P53119
別名：

HUL5; YGL141W; Probable E3 ubiquitin-protein ligase HUL5; EC 2.3.2.26; HECT-type E3 ubiquitin transferase HUL5
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Non essential.
基因功能參考文獻：
1. Review discusses how the Hul5 protein quality control pathway may specifically target low solubility cytosolic proteins in the cell.[Review] PMID: 22561164
2. Hul5 is involved in a cytosolic protein quality control pathway that targets misfolded proteins for degradation. PMID: 21983566
3. support a role for the ATPase subunits in the unfolding of proteasome substrates before insertion into the catalytic cavity and suggest a role for Hul5 in the processive degradation of proteins that are stalled on the proteasome. PMID: 20008553
4. We report here a proteasome-dependent conjugating activity of Hul5 that endows proteasomes with the capacity to extend ubiquitin chains. PMID: 17190603
5. Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation PMID: 18436532
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數據庫鏈接：

KEGG: sce:YGL141W

STRING: 4932.YGL141W