Recombinant Saccharomyces cerevisiae Mitochondrial metalloendopeptidase OMA1 (OMA1), partial

中文名稱：

釀酒酵母OMA1重組蛋白
貨號：

CSB-YP339648SVG1
規(guī)格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母OMA1重組蛋白
貨號：

CSB-EP339648SVG1
規(guī)格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母OMA1重組蛋白
貨號：

CSB-EP339648SVG1-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母OMA1重組蛋白
貨號：

CSB-BP339648SVG1
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母OMA1重組蛋白
貨號：

CSB-MP339648SVG1
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

OMA1
Uniprot No.：

P36163
別名：

OMA1; YKR087C; YKR407; Mitochondrial metalloendopeptidase OMA1
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Protease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OXA1 and COX1. Cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Cleaves the misfolded multi-pass membrane protein OXA1. Involved in quality control of cytochrome oxidase assembly: mediates the cleavage of COX1 in cells lacking COA2. Required for the stability of the respiratory supercomplexes. Required for TOR signaling.
基因功能參考文獻：
1. Study shows that in Saccharomyces cerevisiae, inactivation of the membrane-bound intramitochondrial quality control protease Oma1 interferes with oxidative-stress responses through enhanced production of reactive oxygen species during logarithmic growth and reduced stress signaling via the TORC1-Rim15-Msn2/Msn4 axis. PMID: 27325672
2. yeast Oma1 is an important player in IM protein homeostasis and integrity by acting in concert with other intramitochondrial quality control components. PMID: 24648523
3. Specific Cox1 proteolysis in coa2Delta cells arises from a combination of Oma1 activation and a susceptible conformation of Cox1. PMID: 22219186
亞細胞定位：

Mitochondrion inner membrane; Single-pass membrane protein.
蛋白家族：

Peptidase M48 family
數(shù)據(jù)庫鏈接：

KEGG: sce:YKR087C

STRING: 4932.YKR087C