在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae Heat shock factor protein (HSF1), partial

  • 中文名稱:
    釀酒酵母HSF1重組蛋白
  • 貨號:
    CSB-YP318801SVG
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母HSF1重組蛋白
  • 貨號:
    CSB-EP318801SVG
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母HSF1重組蛋白
  • 貨號:
    CSB-EP318801SVG-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母HSF1重組蛋白
  • 貨號:
    CSB-BP318801SVG
  • 說明書:
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母HSF1重組蛋白
  • 貨號:
    CSB-MP318801SVG
  • 說明書:
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    HSF1; YGL073WHeat shock factor protein; HSF; Heat shock transcription factor; HSTF
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能:
    DNA-binding transcription factor that specifically binds heat shock promoter elements (HSE) and activates transcription.
  • 基因功能參考文獻(xiàn):
    1. we show here that a predicted low-complexity interacting region in the disordered C-terminus of the stress response master regulator heat shock factor 1 (Hsf1) protein corresponds to a cryptic amyloid region able to self-assemble into fibrillary structures resembling those found in neurodegenerative disorders PMID: 29734798
    2. Here the authors show that in budding yeast, Hsf1 basally associates with the chaperone Hsp70 and this association is transiently disrupted by heat shock, providing the first evidence that a chaperone repressor directly regulates Hsf1 activity. PMID: 27831465
    3. Yeast chaperone gene expression is an essential housekeeping mechanism and provides a roadmap for defining the function of HSF1 as a driver of oncogenesis. PMID: 27320198
    4. A characteristic residence time for non-specific interactions of HSF1 transcription factor with chromatin PMID: 27566148
    5. Studies suggest that heat shock factor 1 (Hsf1) controls a set of chaperone protein genes devoted to restoring protein-folding homeostasis in heat shock response. PMID: 27502399
    6. regulation of Hsf1-Skn7 activities by the catalytic subunits of PKA PMID: 26209979
    7. finding show that regulation of the Hsf1 S608 phosphorylation status by reciprocal actions of CK2 and Ppt1 might play an important role to determine Hsf1 sensitivity towards ethanol stress PMID: 24894977
    8. Data indicate that rapamycin inhibition of heat shock transcription factor (Hsf1) can be lost through Hsp90 heat shock protein mutation PMID: 24970820
    9. Rim15 induces expression of Hsf1 target genes upon glucose depletion by both transcriptional activation and stabilization of the transcripts. PMID: 24140345
    10. Mediator recruitment to heat shock genes requires dual Hsf1 activation domains and mediator tail subunits Med15 and Med16. PMID: 23447536
    11. Taken together, these data demonstrate that hyperphosphorylation of Hsf1p caused by loss of the PPT1 gene at least partly accounts for the defective stress response and high ethanol productivity of modern sake yeast strains. PMID: 22057870
    12. Hsf1 is a key transcription factor of HSP90 and mitochondrial HSP genes. Expression of these target genes is necessary for resistance to proteotoxic stress. Hsf1 regulates longevity through mechanisms that are separate from Rim15. PMID: 21827755
    13. Carboxy-terminal region of the yeast heat shock factor contains two domains that mediates Kin28-independent transcription. PMID: 14750950
    14. changes in S. cerevisiae HSF1 transcriptional activity in response to stress might be linked to the combined effects of trehalose and elevated temperatures in modifying the overall structure of HSF1's C-terminal activation domain PMID: 15651035
    15. findings establish the importance of HSF in prion initiation and strain determination and imply a similar regulatory role of mammalian HSFs in the complex etiology of prion disease PMID: 16452152
    16. activates expression of PDR3, encoding a multidrug resistance (MDR) transcription factor that also directly activates RPN4 gene expression. PMID: 16556235
    17. expression of stress proteins are mediated by Rsp5 and that Rsp5 primarily regulates post-translational modification of Hsf1 and Msn4 PMID: 16713599
    18. These in vivo results support a new role for trehalose, where trehalose directly modifies the dynamic range of Hsf1 activity and therefore influences heat shock protein mRNA levels in response to stress. PMID: 17145780
    19. The levels of Hsp90 expression affecting transcription factor regulation by Hsp90 client protein kinases also provides a mechanistic model for how heat shock factor can influence the expression of several non-hsp genes in higher organisms. PMID: 17293484
    20. in response to environmental stresses, Rsp5 primarily regulates the expression of Hsf1 and Msn2/4 at the post-transcriptional level and is involved in the repair system of stress-induced abnormal proteins PMID: 18233954
    21. activated Hsf1 inhibits rapamycin resistance and TOR signaling via elevated expression of specific target genes PMID: 18270585
    22. Hsf1 and Msn2/4 act differentially before and after exposure to extreme temperatures to ensure cell survival and growth. PMID: 18359875

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    HSF family
  • 數(shù)據(jù)庫鏈接:

    KEGG: sce:YGL073W

    STRING: 4932.YGL073W



主站蜘蛛池模板: 男女啪啪免费体验区| 色欲av永久无码精品无码蜜桃| 漂亮人妻洗澡被公强 日日躁| 亚洲爆乳无码精品aaa片蜜桃 | 女人与拘性猛交视频| 玩弄人妻少妇500系列网址| 欧美色欧美亚洲日韩在线播放| 高清乱码一区二区三区| 久久www免费人成_看片中文| 97久久超碰亚洲视觉盛宴| 国产亚洲精品久久久久5区| 久久毛片免费看一区二区三区| 成人午夜亚洲精品无码区| 蜜桃臀无码内射一区二区三区| 亚洲男女羞羞无遮挡久久丫| 久久精品无码免费不卡 | 毛片无码国产| 小嫩妇好紧好爽再快视频| 久久久久欧美国产高潮| 久久久久久无码精品人妻a片软件 999久久久精品国产消防器材 | 欧美大片aaaaa免费观看| 久久综合伊人77777| 日本午夜免费啪视频在线| 天堂8а√中文在线官网| 色噜噜狠狠色综合av| 丰满爆乳一区二区三区| 亚洲欧美日本久久综合网站点击 | 亚洲日韩欧美国产高清αv| 亚洲自偷自偷图片| 免费永久看黄神器无码软件| 国内精品无码一区二区三区| 精品无码久久久久国产| 肉岳疯狂69式激情的高潮| 东方aⅴ免费观看久久av| 美女被啪到深处抽搐视频| 一本无码人妻在中文字幕| 国产肥白大熟妇bbbb视频| 99热这里只就有精品22| 国产饥渴孕妇在线播放| 少妇被躁爽到高潮无码人狍大战| 欧美性xxxx狂欢老少配|