在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae E4 ubiquitin-protein ligase UFD2 (UFD2), partial

  • 中文名稱:
    釀酒酵母UFD2重組蛋白
  • 貨號:
    CSB-YP346986SVG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母UFD2重組蛋白
  • 貨號:
    CSB-EP346986SVG
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母UFD2重組蛋白
  • 貨號:
    CSB-EP346986SVG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母UFD2重組蛋白
  • 貨號:
    CSB-BP346986SVG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母UFD2重組蛋白
  • 貨號:
    CSB-MP346986SVG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    UFD2
  • Uniprot No.:
  • 別名:
    UFD2; YDL190C; D1255E4 ubiquitin-protein ligase UFD2; EC 2.3.2.27; RING-type E3 ubiquitin transferase UFD2; Ubiquitin conjugation factor E4; Ubiquitin fusion degradation protein 2; UB fusion protein 2
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    E4 ubiquitin chain-elongation enzyme specifically involved in polyubiquitin chain assembly. Binds to CDC48 and elongates mono- and diubiquitinated ERAD substrates presented by the UFD1-NPL4-CDC48/p97 (UNC) AAA ATPase complex to a chain length of 4 to 6 ubiquitin moieties. Delivers these polyubiquitinated substrates to RAD23 and DSK2, which target them to the proteasome. Has E3 ubiquitin-protein ligase activity, accepting ubiquitin from its cognate E2 ubiquitin-conjugating enzyme UBC4. Enhances ubiquitination at 'Lys-48', but not at 'Lys-29' of the Ub moiety. Promotes ubiquitin chain elongation at 'Lys-48' on the DOA10 substrate PEX29. Also involved in the proteolytic processing of the ER-bound transcription factor SPT23.
  • 基因功能參考文獻:
    1. Study results suggest that Ufd2p functions by switching ubiquitin chain linkages to allow the degradation of proteins modified with a ubiquitin linkage, which is normally not targeted to the proteasome. PMID: 28165462
    2. The action of Cdc48 could free Rad23 from Ufd2 to allow its subsequent association with Rpn1, which in turn may facilitate the orderly transfer of the substrate from the ubiquitylation apparatus to the proteasome. PMID: 21807993
    3. Data present the crystal structures of Ufd2 in complex with the UBL domains of Rad23 and Dsk2. PMID: 20427284
    4. can function as a bona fide E3 ubiquitin ligase to promote ubiquitin chain elongation on a substrate PMID: 17890322
  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    Ubiquitin conjugation factor E4 family
  • 數據庫鏈接:

    KEGG: sce:YDL190C

    STRING: 4932.YDL190C



主站蜘蛛池模板: 国产美女裸身网站免费观看视频| 国产精品亚洲片在线观看不卡| 欧美xxxx做受欧美69| 亚洲午夜无码极品久久| 色婷婷五月综合久久| 国产成人亚洲日韩欧美| 久久综合av色老头免费观看| 影音先锋每日av色资源站| 久久国产劲爆∧v内射| 日韩高清亚洲日韩精品一区| 最新国产久免费视频在线观看| 亚洲男人的天堂一区二区| 国产高清无密码一区二区三区| 日本乱人伦在线观看| 亚洲熟女乱综合一区二区在线| 国产传媒麻豆剧精品av| 亚洲人成伊人成综合网久久久 | 凸凹人妻人人澡人人添| 3p人妻少妇对白精彩视频| 无码三级av电影在线观看| 国产性天天综合网| 国产精品久久久久久无码 | 国产成久久免费精品av片| 999久久久免费精品国产| 么公的好大好硬好深好爽视频| 东京热一精品无码av| 国内精品久久久久久久电影视 | 日韩精品一区二区av在线观看 | а√天堂8资源在线官网| 一本一道波多野结衣av黑人| 四虎成人永久在线精品免费| 亚洲乱码中文字幕综合234| 欧美午夜刺激影院| 国产毛a片啊久久久久久保和丸 | 国产在线播放精品视频| 天堂中文官网在线| 亚洲狠狠婷婷综合久久蜜芽| 日韩精品无码免费专区午夜不卡| 蜜臀av999无码精品国产专区 | 欧美性白人极品1819hd| 成人欧美一区二区三区1314|