在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Saccharomyces cerevisiae DNA topoisomerase 2 (TOP2), partial

  • 中文名稱:
    釀酒酵母TOP2重組蛋白
  • 貨號:
    CSB-YP361947SVG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    釀酒酵母TOP2重組蛋白
  • 貨號:
    CSB-EP361947SVG
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    釀酒酵母TOP2重組蛋白
  • 貨號:
    CSB-EP361947SVG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    釀酒酵母TOP2重組蛋白
  • 貨號:
    CSB-BP361947SVG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    釀酒酵母TOP2重組蛋白
  • 貨號:
    CSB-MP361947SVG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    TOP2; TOR3; YNL088W; N2244; DNA topoisomerase 2; EC 5.6.2.2; DNA topoisomerase II
  • 種屬:
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes.
  • 基因功能參考文獻:
    1. Condensin DNA supercoiling activity correlates with Top2 intertwine removal during DNA replication. PMID: 27716481
    2. Topoisomerase II plays a central role in a molecular pathway for crossover interference PMID: 25043020
    3. Chromatin regulates DNA torsional energy via topoisomerase II-mediated relaxation of positive supercoils. PMID: 24859967
    4. the cell cycle delay depends on the divergent and catalytically inert C-terminal region of Topo II, indicating that transmission of a checkpoint signal may occur via the C-terminus PMID: 24098144
    5. Structure of topoisomerase II-DNA-nucleotide complex produces an unexpected interaction between DNA and a conformational transducing element in the ATPase domain, which is critical for both DNA-stimulated ATP hydrolysis and global topoisomerase activity. PMID: 23022727
    6. a topological change on DNA drives topoisomerase II to decatenate molecules during mitosis, potentially driving the full decatenation of the genome PMID: 21393545
    7. In eukaryotes, replication fork barriers, Rrm3, and Top2 coordinate replication fork progression and fusion at chromosomal termination regions, thus counteracting abnormal genomic transitions. PMID: 20797631
    8. structure of the DNA-binding and cleavage core of Saccharomyces cerevisiae topoisomerase II covalently linked to DNA through its active-site tyrosine at 2.5A resolution PMID: 20485342
    9. compromised Topo II function activates a yeast checkpoint system that operates by a novel mechanism PMID: 16651657
    10. structure of a complex between the DNA-binding and cleavage core of Saccharomyces cerevisiae Topo II (also known as Top2) and a gate-DNA segment PMID: 18097402
    11. kinetic and structural analysis of coupling between ATP binding and DNA cleavage by DNA topoisomerase II PMID: 18403371
    12. Top2 seems to play a novel role in centromeric chromatin compaction that is distinct from decatenation PMID: 18701701
    13. analysis of Top2 covalent complexes containing DNA single strand breaks PMID: 18723844

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Type II topoisomerase family
  • 數據庫鏈接:

    KEGG: sce:YNL088W

    STRING: 4932.YNL088W



主站蜘蛛池模板: 无码三级中文字幕在线观看| 香蕉免费一区二区三区| 日韩精品一区二区三区在线观看l 亚洲在av人极品无码 | 中文国产成人精品久久不卡 | 久久www免费人成一看片| 少妇无码一区二区二三区| 久久视频这里只精品| 又爽又黄又无遮挡的激情视频| 亚洲人成网7777777国产| 国产成人精品一区二三区在线观看| 亚洲国产成人av人片久久| 久久久一本精品99久久精品66直播| 少妇激情艳情综合小视频| 日出水了特别黄的视频| 国产午夜鲁丝无码拍拍| 亚洲免费福利在线视频| 免费人成小说在线观看网站| 亚洲欧美日韩成人高清在线一区| 国产有奶水哺乳期无码avav| 人妻.中文字幕无码| 一本一道久久a久久精品综合| 三男一女吃奶添下面视频| 免费无码成人av在线播| 丰满的少妇hd高清中文字幕| 日本50岁丰满熟妇xxxx| 高清精品一区二区三区| 国产xxx视频在线观看软件| 亚洲日韩欧美一区二区三区| 成品人视频ww入口| 伊人色综合网一区二区三区| 国产又色又爽又黄的在线观看| 丁香五月欧美成人| 永久免费精品精品永久-夜色| 2018年秋霞无码片| 激情爆乳一区二区三区| 国产美女在线精品免费观看| 真实国产精品vr专区| 国产精品99久久久久久董美香| 久久久久久av无码免费网站下载| 色欲综合久久躁天天躁蜜桃| 亚洲s久久久久一区二区|