Recombinant Saccharomyces cerevisiae Cardiolipin-specific deacylase 1, mitochondrial (CLD1)

中文名稱：

Recombinant Saccharomyces cerevisiae Cardiolipin-specific deacylase 1, mitochondrial(CLD1)
貨號(hào)：

CSB-YP346066SVG
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cardiolipin-specific deacylase 1, mitochondrial(CLD1)
貨號(hào)：

CSB-EP346066SVG
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cardiolipin-specific deacylase 1, mitochondrial(CLD1)
貨號(hào)：

CSB-EP346066SVG-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cardiolipin-specific deacylase 1, mitochondrial(CLD1)
貨號(hào)：

CSB-BP346066SVG
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Saccharomyces cerevisiae Cardiolipin-specific deacylase 1, mitochondrial(CLD1)
貨號(hào)：

CSB-MP346066SVG
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CLD1
Uniprot No.：

P53264
別名：

CLD1; YGR110W; G6140Cardiolipin-specific deacylase 1; mitochondrial; EC 3.5.1.-
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Full Length of Mature Protein
表達(dá)區(qū)域：

40-445
氨基酸序列

V TEKQILRTPS APTAIPLREI IYRVPSLFPR PLEDSVKDFR DFIKNEDAFQ TELLKTLPFY PTPSESKTAR LIRTVVDDEG NYINEFCIRP RKTSVPEADL KHLVFIHGYG AGLGFFIKNF EDIPLLDNEW CIHAIDLPGY GFSSRPKFPF EYPRDNIHSV QDWFHERIHT WFSKRNLLNR PEKNIVMAHS LGSYLMALYL QKYKESPSFK KLILCSPAGV SYRDFNNTAS EVEKWKPPPW WYVKLWDRNI SPFTLVRNFR QLGSKITSGW SYRRFKHILN GDPEQSKRFE ALHRYAYAIF NKRGSGEYLL SFALKCGGEP RLSLEQQLFD GKKSDILKNS NCDWLWLYGD DDWMDVNGGL RVSRFLKEKL KQKSNVIIVP HSGHHLYLDN YKFFNNILTK EMQKI
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Mitochondrial cardiolipin-specific phospholipase which deacylates de novo synthesized cardiolipin (CL). Part of the remodeling process of cardiolipin, which involves deacylation-reacylation of premature cardiolipin. Has a strong substrate preference for palmitic acid residues and generates monolysocardiolipin (MLCL) for TAZ1-dependent reacylation with unsaturated fatty acids. The hydrolytic selectivity of the enzyme toward C16-CL substrates contributes to the preservation of C18:1-containing CL species. Has high specificity towards peroxidized cardiolipids CL(OX). Required to mitigate oxidative stress by removing CL(OX).
基因功能參考文獻(xiàn)：
1. transcriptional regulation of Cld1-mediated deacylation of CL influences energy metabolism by modulating the relative contribution of glycolysis and respiration. PMID: 24318983
2. Data indicate that monolysocardiolipin generated by Cld1p must be transported to intermembrane space (IMS)-facing membrane leaflets to gain access to tafazzin (TAZ1) for cardiolipin (CL) remodeling. PMID: 23637464
3. YGR110W (CLD1) is a cardiolipin-specific phospholipase PMID: 19244244
亞細(xì)胞定位：

Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
蛋白家族：

Peptidase S33 family, ABHD4/ABHD5 subfamily
數(shù)據(jù)庫鏈接：

KEGG: sce:YGR110W

STRING: 4932.YGR110W