在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Rat Voltage-gated potassium channel subunit beta-2 (Kcnab2)

  • 中文名稱:
    大鼠Kcnab2重組蛋白
  • 貨號:
    CSB-YP012014RA
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    大鼠Kcnab2重組蛋白
  • 貨號:
    CSB-EP012014RA
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    大鼠Kcnab2重組蛋白
  • 貨號:
    CSB-EP012014RA-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    大鼠Kcnab2重組蛋白
  • 貨號:
    CSB-BP012014RA
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    大鼠Kcnab2重組蛋白
  • 貨號:
    CSB-MP012014RA
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Kcnab2
  • Uniprot No.:
  • 別名:
    Kcnab2; Ckbeta2; Kcnb3; Voltage-gated potassium channel subunit beta-2; EC 1.1.1.-; K(+) channel subunit beta-2; Kv-beta-2
  • 種屬:
    Rattus norvegicus (Rat)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-367
  • 氨基酸序列
    MYPESTTGSP ARLSLRQTGS PGMIYSTRYG SPKRQLQFYR NLGKSGLRVS CLGLGTWVTF GGQITDEMAE HLMTLAYDNG INLFDTAEVY AAGKAEVVLG NIIKKKGWRR SSLVITTKIF WGGKAETERG LSRKHIIEGL KASLERLQLE YVDVVFANRP DPNTPMEETV RAMTHVINQG MAMYWGTSRW SSMEIMEAYS VARQFNLIPP ICEQAEYHMF QREKVEVQLP ELFHKIGVGA MTWSPLACGI VSGKYDSGIP PYSRASLKGY QWLKDKILSE EGRRQQAKLK ELQAIAERLG CTLPQLAIAW CLRNEGVSSV LLGASNAEQL MENIGAIQVL PKLSSSIVHE IDSILGNKPY SKKDYRS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Cytoplasmic potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expression of the pore-forming alpha subunits at the cell membrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Modulates the functional properties of KCNA4. Modulates the functional properties of KCNA5. Enhances KCNB2 channel activity. Binds NADPH and has NADPH-dependent aldoketoreductase activity. Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro).
  • 基因功能參考文獻:
    1. Data suggest that potassium channel Kvbeta2 inhibitors could serve as tools to decipher the role of Kvbeta2 in vivo and, eventually, inform the development of novel therapeutics. PMID: 25066316
    2. Article reports a newly identified protein-protein interaction between the PSD-protein ProSAP2/Shank3 and the voltage-gated potassium channel subunit Kvbeta2 PMID: 24211303
    3. Kvbeta2 catalyzed the NADPH-dependent reduction of several products of oxPAPC PMID: 21296056
    4. ZIP3 formed dimers with ZIP1-3 and interacted with PKC-zeta and the shaker-type potassium channel subunit Kv beta 2 PMID: 12431995
    5. There is a possibility that the K+ voltage-gated channel function is modulated by its beta-subunit. PMID: 14569011
    6. identification of Kvbeta2 substrates and the demonstration that Kvbeta2 is a functional aldo-keto reductase PMID: 16569641

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Cell junction, synapse, synaptosome. Cytoplasm, cytoskeleton.
  • 蛋白家族:
    Shaker potassium channel beta subunit family
  • 組織特異性:
    Detected in brain. Detected in the middle third of the molecular layer of the dentate gyrus in hippocampus. Detected in neurons in the deep cerebellar nucleus. Detected in globus pallidus and pars reticulata of the substantia nigra. Detected in cerebellum
  • 數據庫鏈接:


主站蜘蛛池模板: 热99re久久精品| 图片区小说区亚洲欧美自拍| 亚洲乱码日产精品bd在| 国产精品久久久久无码av1| 好吊妞国产欧美日韩免费观看| 久久久亚洲欧洲日产国码农村| 亚洲日韩国产精品乱-久| 亚洲色爱免费观看视频| 99久久亚洲精品无码毛片| 国产精品久久久久久久9999| 久久99青青精品免费观看| 亚洲国产精品无码久久| 男人扒开女人腿桶到爽免费 | 麻花传媒mv在线观看| 亚洲—本道 在线无码av发| 亚洲一区天堂九一| 国产午夜鲁丝无码拍拍| 国产色无码精品视频国产| 国产精品不卡无码av在线播放 | 精品久久亚洲中文无码| 看国产黄大片在线观看| 国产成人av在线播放影院| 国产小受呻吟gv视频在线观看| 亚洲国产成人久久综合一区| 免费无码久久成人影片| 日韩内射美女片在线观看网站| 久久久久国产精品熟女影院| 又爽又黄又无遮挡的视频| 久久久久国精品产熟女久色| 曰批免费视频播放免费直播| 亚洲国产欧美在线人成aaaa| 无码丰满熟妇| 国产人成网线在线播放va| 亚洲成a人片在线观看的电影| 国产亚洲精品俞拍视频| 日本大胆欧美人术艺术| 亚洲精品午夜理伦不卡在线观看| 免费人成在线观看网站| 日本亚洲色大成网站www| 久久国产福利一区二区| 国产成人综合久久精品|